2021
Perinatal and birth correlates of childhood irritability in Taiwan's national epidemiological study
Lee KS, Xiao J, Liew Z, Gau SS, Tseng WL. Perinatal and birth correlates of childhood irritability in Taiwan's national epidemiological study. Journal Of Affective Disorders 2021, 299: 273-280. PMID: 34906640, PMCID: PMC8767526, DOI: 10.1016/j.jad.2021.12.016.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentFemaleHumansIrritable MoodMood DisordersProspective StudiesReproducibility of ResultsRetrospective StudiesTaiwanConceptsNational epidemiological studyBirth characteristicsEpidemiological studiesChildhood irritabilityEarly life exposureAdverse mental healthBirth correlatesPerinatal perspectiveVaginal bleedingMaternal smokingAffective Reactivity IndexPerinatal risksBirth factorsLife exposureProspective assessmentIrritabilityTemper outburstsRecall biasLife outcomesPerinatalMental healthEarly etiologyChild irritabilityRetrospective assessmentEnvironmental exposuresNeural correlates of extinguished threat recall underlying the commonality between pediatric anxiety and irritability
Tseng WL, Abend R, Gold AL, Brotman MA. Neural correlates of extinguished threat recall underlying the commonality between pediatric anxiety and irritability. Journal Of Affective Disorders 2021, 295: 920-929. PMID: 34706463, PMCID: PMC8554134, DOI: 10.1016/j.jad.2021.08.117.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxietyAnxiety DisordersChildHumansIrritable MoodMagnetic Resonance ImagingMental RecallPrefrontal CortexReproducibility of ResultsConceptsHigh negative affectivityNegative affectivityThreat appraisalPediatric anxietyAnxiety disordersThreat-safety discriminationWhole-brain activationLinear mixed effects analysisNegative affectivity factorExtinction recallThreat conditioningThreat contingenciesElevated irritabilityNeural correlatesTransdiagnostic sampleGreater prefrontalOccipital activationUnique varianceExplicit recallThreat responsesFMRI paradigmNeural mechanismsTask conditionsAmygdala connectivityMixed effects analysis
2017
Test-retest reliability and validity of a frustration paradigm and irritability measures
Tseng WL, Moroney E, Machlin L, Roberson-Nay R, Hettema JM, Carney D, Stoddard J, Towbin KA, Pine DS, Leibenluft E, Brotman MA. Test-retest reliability and validity of a frustration paradigm and irritability measures. Journal Of Affective Disorders 2017, 212: 38-45. PMID: 28135689, PMCID: PMC8049456, DOI: 10.1016/j.jad.2017.01.024.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChecklistChildFemaleFrustrationHumansIrritable MoodMaleParentsPersonality TestsReproducibility of ResultsSelf ReportSurveys and QuestionnairesConceptsTest-retest reliabilityParent-reported irritabilityIrritability measuresGood test-retest reliabilityNegative affectIrritability ScaleValidity of assessmentsBehavioral paradigmsChild irritabilityTreatment researchGeneral population sampleConvergent validityExcellent test-retest reliabilityModest supportConstruct validityTaskParticipantsIrritabilityParadigmIntraclass correlation
2015
Neural correlates of masked and unmasked face emotion processing in youth with severe mood dysregulation
Tseng WL, Thomas LA, Harkins E, Pine DS, Leibenluft E, Brotman MA. Neural correlates of masked and unmasked face emotion processing in youth with severe mood dysregulation. Social Cognitive And Affective Neuroscience 2015, 11: 78-88. PMID: 26137973, PMCID: PMC4692312, DOI: 10.1093/scan/nsv087.Peer-Reviewed Original ResearchConceptsSevere mood dysregulationFace emotion processingFunctional magnetic resonance imagingEmotion processingParahippocampal gyrusNeural correlatesMood dysregulationVentromedial prefrontal cortex activationAffective priming paradigmPrefrontal cortex activationSuperior temporal gyrusAngry facesFace processingHappy facesSMD patientsPositive emotionsPriming paradigmVmPFC dysfunctionNegative emotionsTemporal gyrusCortex activationEmotionsFMRI dataDecreased activationIndependent samples