2021
Primary Care of Adult Patients After Stroke: A Scientific Statement From the American Heart Association/American Stroke Association
Kernan WN, Viera AJ, Billinger SA, Bravata DM, Stark SL, Kasner SE, Kuritzky L, Towfighi A, Arteriosclerosis T. Primary Care of Adult Patients After Stroke: A Scientific Statement From the American Heart Association/American Stroke Association. Stroke 2021, 52: e558-e571. PMID: 34261351, DOI: 10.1161/str.0000000000000382.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAmerican Heart AssociationHumansMiddle AgedPrimary Health CareStrokeUnited StatesConceptsRecurrent strokePoststroke carePrimary careAmerican Heart Association/American Stroke AssociationOngoing functional impairmentPatient-centered primary careAmerican Stroke AssociationHigh blood pressureEvidence-based carePrimary care practicesPrimary care teamsPatient-centered careQuality of lifePoststroke managementLifestyle modificationAdult patientsLate complicationsQuality improvement strategiesBlood pressureAtrial fibrillationCarotid stenosisStroke AssociationOngoing careRisk factorsCare team
2005
Association between Impaired Insulin Sensitivity and Stroke
Bravata DM, Wells CK, Kernan WN, Concato J, Brass LM, Gulanski BI. Association between Impaired Insulin Sensitivity and Stroke. Neuroepidemiology 2005, 25: 69-74. PMID: 15947493, DOI: 10.1159/000086286.Peer-Reviewed Original ResearchConceptsHomeostasis model assessmentInsulin sensitivityGlycemic controlMultivariable logistic regression analysisStroke risk factorsLower insulin sensitivityThird National HealthImpaired insulin sensitivityLogistic regression analysisStroke historyInsulin resistancePlasma insulinPlasma glucoseRisk factorsNational HealthNutrition SurveyModel assessmentStrokeRegression analysisAssociationParticipantsClaudicationInsulinRacial Disparities in Stroke Risk Factors
Bravata DM, Wells CK, Gulanski B, Kernan WN, Brass LM, Long J, Concato J. Racial Disparities in Stroke Risk Factors. Stroke 2005, 36: 1507-1511. PMID: 15961710, DOI: 10.1161/01.str.0000170991.63594.b6.Peer-Reviewed Original ResearchConceptsStroke risk factorsRisk factorsStroke historyHigh prevalenceLow high-density lipoprotein cholesterolHigher C-reactive proteinHigh-density lipoprotein cholesterolCommunity-dwelling stroke survivorsC-reactive proteinThird National HealthSevere strokeLipoprotein cholesterolMyocardial infarctionNational HealthStroke survivorsNutrition SurveyHigh incidenceUS populationStrokeOlder ageCross-sectional samplePrevalenceRacial disparitiesEthnic differencesAssociationEstrogen therapy and risk of cognitive decline: Results from the Women's Estrogen for Stroke Trial (WEST)
Viscoli CM, Brass LM, Kernan WN, Sarrel PM, Suissa S, Horwitz RI. Estrogen therapy and risk of cognitive decline: Results from the Women's Estrogen for Stroke Trial (WEST). American Journal Of Obstetrics And Gynecology 2005, 192: 387-393. PMID: 15695976, DOI: 10.1016/j.ajog.2004.08.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCognitionDouble-Blind MethodEstradiolFemaleHumansMiddle AgedPostmenopauseStrokeConceptsMini-Mental State ExaminationEstrogen therapyCognitive declineNormal Mini-Mental State ExaminationDouble-blind trialSecondary stroke preventionTransient ischemic attackIschemic attackPostmenopausal womenStroke preventionRecent strokeStroke trialsCerebrovascular diseaseWomen's EstrogenEstradiol-17betaState ExaminationCognitive measuresEstrogenWomenNormal functionDomain measuresLess declineTherapyStrokeRiskPrevalence of Abnormal Glucose Tolerance Following a Transient Ischemic Attack or Ischemic Stroke
Kernan WN, Viscoli CM, Inzucchi SE, Brass LM, Bravata DM, Shulman GI, McVeety JC. Prevalence of Abnormal Glucose Tolerance Following a Transient Ischemic Attack or Ischemic Stroke. JAMA Internal Medicine 2005, 165: 227-233. PMID: 15668371, DOI: 10.1001/archinte.165.2.227.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionAgedAged, 80 and overBlood GlucoseCohort StudiesFemaleGlucose IntoleranceGlucose Tolerance TestHumansIschemic Attack, TransientLogistic ModelsMaleMiddle AgedOdds RatioPrevalenceProbabilityPrognosisProspective StudiesRisk AssessmentSeverity of Illness IndexSex DistributionStrokeConceptsTransient ischemic attackDiabetic glucose toleranceImpaired glucose toleranceAbnormal glucose tolerancePlasma glucose levelsRecent transient ischemic attackGlucose toleranceIschemic strokeGlucose levelsIschemic attackPhysician-diagnosed diabetes mellitusOral glucose tolerance testStepwise logistic regression modelIncident vascular diseaseRecurrent brain diseaseVascular disease mortalityHistory of diabetesClinical Research CenterGlucose tolerance testLower waist circumferencePlasma glucose valuesForward stepwise logistic regression modelLogistic regression modelsEligible patientsAntihyperglycemic therapy
2004
Two measures of insulin sensitivity provided similar information in a U.S. population
Bravata DM, Wells CK, Concato J, Kernan WN, Brass LM, Gulanski BI. Two measures of insulin sensitivity provided similar information in a U.S. population. Journal Of Clinical Epidemiology 2004, 57: 1214-1217. PMID: 15567640, DOI: 10.1016/j.jclinepi.2004.05.001.Peer-Reviewed Original Research
2002
Clinical assessment of function among women with a recent cerebrovascular event: a self-reported versus performance-based measure.
Owens PL, Bradley EH, Horwitz SM, Viscoli CM, Kernan WN, Brass LM, Sarrel PM, Horwitz RI. Clinical assessment of function among women with a recent cerebrovascular event: a self-reported versus performance-based measure. Annals Of Internal Medicine 2002, 136: 802-11. PMID: 12044128, DOI: 10.7326/0003-4819-136-11-200206040-00008.Peer-Reviewed Original ResearchConceptsLong-term health outcomesRecent cerebrovascular eventsLevel of functionCerebrovascular eventsPerformance-based measuresHealth outcomesSelf-reported functional statusTransient ischemic attackProspective cohort studyPhysical performance testsSelf-report measuresIschemic attackPostmenopausal womenBarthel IndexCohort studyNonwhite ethnicityFunctional statusClinical assessmentMost womenHealth measuresClinical settingSubsequent strokeWomenOutcomesStroke
2001
A Clinical Trial of Estrogen-Replacement Therapy after Ischemic Stroke
Viscoli C, Brass L, Kernan W, Sarrel P, Suissa S, Horwitz R. A Clinical Trial of Estrogen-Replacement Therapy after Ischemic Stroke. New England Journal Of Medicine 2001, 345: 1243-1249. PMID: 11680444, DOI: 10.1056/nejmoa010534.Peer-Reviewed Original ResearchConceptsEstrogen replacement therapyEstrogen therapyNonfatal strokePostmenopausal womenIschemic strokeCerebrovascular diseasePlacebo-controlled trialTransient ischemic attackOccurrence of strokeRisk of deathIschemic attackFatal strokeMean followPlacebo groupSecondary preventionEstradiol groupFunctional deficitsClinical trialsObservational studyHigh riskWoman's riskTherapyStrokeWomenDeath
2000
Blood Pressure Exceeding National Guidelines Among Women After Stroke
Kernan W, Viscoli C, Brass L, Makuch R, Sarrel P, Horwitz R. Blood Pressure Exceeding National Guidelines Among Women After Stroke. Stroke 2000, 31: 415-419. PMID: 10657415, DOI: 10.1161/01.str.31.2.415.Peer-Reviewed Original ResearchConceptsHistory of hypertensionBlood pressure valuesNational guidelinesBlood pressureFirst examinationTrial of estrogenSecondary stroke preventionTransient ischemic attackBlood pressure controlTreatment of hypertensionProportion of womenIschemic attackSevere hypertensionStroke preventionSecondary preventionDiabetic patientsMean ageHypertensionPatientsPressure valuesPersonal physicianPressure controlSeparate guidelinesStrokeWomen
1994
Incidence of hospitalization for digitalis toxicity among elderly Americans
Kernan W, Castellsague J, Perlman G, Ostfeld A. Incidence of hospitalization for digitalis toxicity among elderly Americans. The American Journal Of Medicine 1994, 96: 426-431. PMID: 8192174, DOI: 10.1016/0002-9343(94)90169-4.Peer-Reviewed Original ResearchConceptsIncidence of hospitalizationDigitalis useGastrointestinal symptomsDigitalis toxicityICD-9 codesUse of quinidineAdverse drug reactionsManifestations of toxicityYale HealthObservational cohortHeart blockAlternate therapyDrug reactionsMedical recordsInternational ClassificationHospitalizationElderly AmericansIncidenceNew HavenDigitalisAging ProjectSymptomsPrevalenceToxicityYears