2003
Major Risk Factors for Aneurysmal Subarachnoid Hemorrhage in the Young Are Modifiable
Broderick JP, Viscoli CM, Brott T, Kernan WN, Brass LM, Feldmann E, Morgenstern LB, Wilterdink JL, Horwitz RI. Major Risk Factors for Aneurysmal Subarachnoid Hemorrhage in the Young Are Modifiable. Stroke 2003, 34: 1375-1381. PMID: 12764233, DOI: 10.1161/01.str.0000074572.91827.f4.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionBody Mass IndexCase-Control StudiesCocaine-Related DisordersCohort StudiesComorbidityCooperative BehaviorFemaleHumansHypertensionLogistic ModelsMaleMiddle AgedOdds RatioPhenylpropanolamineRisk FactorsSex DistributionSmokingStrokeSubarachnoid HemorrhageThinnessUnited StatesConceptsAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageRisk factorsLower body mass indexIndependent risk factorCurrent cigarette smokersPrevalent risk factorsBody mass indexMajor risk factorCase-control studyYears of ageRandom digit dialingWarrants further studyHemorrhagic strokeIntracerebral hemorrhageCigarette smokersMass indexPreventable diseaseWomen 18Multivariable modelFamily historyCase subjectsAssociation of caffeineCocaine useHemorrhage
2002
Insulin resistance and risk for stroke
Kernan WN, Inzucchi SE, Viscoli CM, Brass LM, Bravata DM, Horwitz RI. Insulin resistance and risk for stroke. Neurology 2002, 59: 809-815. PMID: 12349850, DOI: 10.1212/wnl.59.6.809.Peer-Reviewed Original ResearchConceptsInsulin resistanceRisk factorsProspective observational cohort studyType 2 diabetes mellitusInsulin-mediated glucose uptakeObservational cohort studyPrevalent risk factorsImportant risk factorType 2 diabetesCase-control studyPertinent English-language publicationsEnglish-language publicationsCardinal defectsPhysical deconditioningStroke preventionCohort studyMost patientsDiabetes mellitusPathophysiologic defectsNondiabetic individualsVascular diseasePeripheral tissuesElderly personsStrokeDefective glycogen synthesis