Ultrastructural localization of albumin transport across the cerebral microvasculature during experimental meningitis in the rat.
Quagliarello V, Ma A, Stukenbrok H, Palade G. Ultrastructural localization of albumin transport across the cerebral microvasculature during experimental meningitis in the rat. Journal Of Experimental Medicine 1991, 174: 657-672. PMID: 1875166, PMCID: PMC2118932, DOI: 10.1084/jem.174.3.657.Peer-Reviewed Original ResearchConceptsBlood-brain barrierBBB injuryExperimental meningitisCerebral microvasculatureOpen intercellular junctionsSpecific therapeutic interventionsBacterial meningitisBrain barrierIntracisternal inoculationMeningitisBrain cortexInjury mechanismMicrovascular segmentsTherapeutic interventionsIntercellular junctionsInducible increaseAu-BSAInjuryAbluminal sidePrecise mechanismSimilar uptakeAlbumin transportColloidal carbonTracer perfusionVenular leaks