Streptozotocin for Malignant Insulinomas and Carcinoid Tumor: Report of Eight Cases and Review of the Literature
Schein P, Kahn R, Gorden P, Wells S, DeVita V. Streptozotocin for Malignant Insulinomas and Carcinoid Tumor: Report of Eight Cases and Review of the Literature. JAMA Internal Medicine 1973, 132: 555-561. DOI: 10.1001/archinte.1973.03650100069013.Peer-Reviewed Original ResearchMalignant insulinomaBone marrow depressionDrug dose levelsPeak serum concentrationComplete remissionMarrow depressionMetastatic insulinomaObjective responseCarcinoid tumorsMalignant carcinoidSerum concentrationsInfusion rateLow doseStreptozotocinDose levelsInjection sitePatientsInsulinomaLimited responseRemissionCarcinoidsResponseChemotherapyPainTumorsStreptozotocin for malignant insulinomas and carcinoid tumor. Report of eight cases and review of the literature.
Schein P, Kahn R, Gorden P, Wells S, Devita V. Streptozotocin for malignant insulinomas and carcinoid tumor. Report of eight cases and review of the literature. JAMA Internal Medicine 1973, 132: 555-61. PMID: 4355081, DOI: 10.1001/archinte.132.4.555.Peer-Reviewed Original ResearchMeSH KeywordsAdenoma, Islet CellAdultBlood GlucoseCarcinoid TumorChemical and Drug Induced Liver InjuryCreatinineFemaleFollow-Up StudiesHumansInsulinKidneyKidney Function TestsLiverLiver NeoplasmsMaleMiddle AgedNeoplasm MetastasisPancreatic NeoplasmsProinsulinProteinuriaRadionuclide ImagingRemission, SpontaneousStreptozocinTime FactorsTolbutamide