Inflammation Sub-Group Analysis in Pediatric HA-VTE Cases: A Report from the Children's Hospital Acquired Thrombosis Registry (CHAT) Registry
Harp T, Proctor K, Mosha M, Cox A, Jaffray J, Stillings A, Krava E, Amankwah E, Faustino E, Zakai N, Young G, Goldenberg N, Branchford B. Inflammation Sub-Group Analysis in Pediatric HA-VTE Cases: A Report from the Children's Hospital Acquired Thrombosis Registry (CHAT) Registry. Blood 2023, 142: 4015. DOI: 10.1182/blood-2023-190491.Peer-Reviewed Original ResearchPast medical historyInflammatory disease diagnosisHA-VTEDischarge diagnosisSystemic inflammationChronic inflammationAcute inflammationInflammatory diseasesOdds ratioCentral venous catheter placementAdmission/transferDays of dischargeLong-term morbidityVenous catheter placementOrgan system involvementPediatric patient populationType of inflammationClinical research effortsSub-group analysisUnderlying risk factorsInstitutional review boardElectronic health recordsChronic varietyHospital stayVenous thromboembolismDerivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock*
Sanchez-Pinto L, Bennett T, Stroup E, Luo Y, Atreya M, Bubeck Wardenburg J, Chong G, Geva A, Faustino E, Farris R, Hall M, Rogerson C, Shah S, Weiss S, Khemani R. Derivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock*. Pediatric Critical Care Medicine 2023, 24: 795-806. PMID: 37272946, PMCID: PMC10540758, DOI: 10.1097/pcc.0000000000003292.Peer-Reviewed Original ResearchMultiple organ dysfunction syndromeSepsis-associated multiple organ dysfunction syndromePersistent hypoxemiaAdjuvant therapySepsis phenotypesSevere pediatric acute respiratory distress syndromePediatric acute respiratory distress syndromeMulticenter observational cohort studyAcute respiratory distress syndromePropensity score-matched analysisCommon adjuvant therapyHeterogeneity of sepsisOrgan dysfunction syndromeObservational cohort studyRespiratory distress syndromeHospital mortalityCohort studyDysfunction syndromeSystemic inflammationDistress syndromeOrgan dysfunctionSeptic shockClinical syndromeCommon therapyClinical relevance