2017
Comparing available criteria for measuring brain metastasis response to immunotherapy
Qian JM, Mahajan A, Yu JB, Tsiouris AJ, Goldberg SB, Kluger HM, Chiang VL. Comparing available criteria for measuring brain metastasis response to immunotherapy. Journal Of Neuro-Oncology 2017, 132: 479-485. PMID: 28275886, DOI: 10.1007/s11060-017-2398-8.Peer-Reviewed Original ResearchConceptsRECIST 1.1Brain lesionsBrain metastasesDurable responsesAdditional patientsNeuro-Oncology Working GroupBrain metastasis responseBrain metastasis patientsUntreated brain metastasesStandardized response criteriaBrain lesion sizeHigh-grade gliomasSimilar clinical trialsHigh-resolution MRIMetastasis patientsMetastasis responseOngoing trialsClinical trialsNovel therapiesResponse assessmentDiscordant casesLesion sizePatientsResponse rateLongest diameter
2016
Predicting treatment related imaging changes (TRICs) after radiosurgery for brain metastases using treatment dose and conformality metrics.
Taylor BF, Knisely JP, Qian JM, Yu JB, Chiang VL. Predicting treatment related imaging changes (TRICs) after radiosurgery for brain metastases using treatment dose and conformality metrics. Journal Of Radiosurgery And SBRT 2016, 4: 53-60. PMID: 29296426, PMCID: PMC5658837.Peer-Reviewed Original ResearchTreatment-related imaging changesPrescription isodose volumeConformity indexStereotactic radiosurgeryTumor volumeGamma Knife stereotactic radiosurgeryRadiation dose volumeSmall-volume lesionsPaddick conformity indexPost-treatment periodBrain metastasesAdditional patientsImaging changesDifferent post-treatment periodsTransient enlargementTreatment doseIsodose volumeRadiographic lesionsVolume lesionsClinical decisionDose volumeMetastasisTreatment factorsMonthsMonth period