2023
From “disappointing” to “fantastic”: Women's experiences with labor induction in a U.S. tertiary hospital
Danilack V, Siegel‐Reamer L, Lum L, Kesselring C, Brousseau E, Guthrie K. From “disappointing” to “fantastic”: Women's experiences with labor induction in a U.S. tertiary hospital. Birth 2023, 50: 959-967. PMID: 37475194, DOI: 10.1111/birt.12750.Peer-Reviewed Original ResearchConceptsLabor inductionSemi-structured qualitative interviewsQualitative interviewsPersonal toleranceSide effectsWay interventionsMother-baby unitFoley balloon catheterProcess of careQuality of careShape patient experiencesInterview questionsPerceptionInduction patientsTertiary hospitalBalloon catheterPatients' perceptionsDifferent interventionsSeries of interventionsPatient experienceHealth outcomesInterventionWomen's perceptionsBirthing processExpectationsPredicting primary cesarean delivery in pregnancies complicated by gestational diabetes mellitus
Ramos S, Lewkowitz A, Lord M, Has P, Danilack V, Savitz D, Werner E. Predicting primary cesarean delivery in pregnancies complicated by gestational diabetes mellitus. American Journal Of Obstetrics And Gynecology 2023, 229: 549.e1-549.e16. PMID: 37290567, PMCID: PMC10700654, DOI: 10.1016/j.ajog.2023.06.002.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusDiabetes mellitusHosmer-Lemeshow testRisk factorsPrimary CDCD riskThird trimesterEarly pregnancy body mass indexPregnancy body mass indexLarge tertiary care centerOlder maternal ageTertiary care centerTrial of laborCohort of patientsBody mass indexImportant clinical outcomesPrimary cesarean deliveryWeeks of gestationMultiple risk factorsCharacteristic curveLogistic regression modelsSimilar discriminatory abilityMultiparous patientsStepwise backward eliminationCesarean deliveryReduced Compared With Traditional Schedules for Routine Antenatal Visits
Balk E, Danilack V, Bhuma M, Cao W, Adam G, Konnyu K, Peahl A. Reduced Compared With Traditional Schedules for Routine Antenatal Visits. Obstetrics And Gynecology 2023, 142: 8-18. PMID: 37290105, DOI: 10.1097/aog.0000000000005193.Peer-Reviewed Original ResearchConceptsRoutine antenatal visitsAntenatal care visitsVisit scheduleAntenatal visitsAntenatal careCare visitsGestational ageNeonatal intensive care unit admissionIntensive care unit admissionRoutine antenatal care visitsCare unit admissionLow Apgar scoreLow birth weightHealth care utilizationNonrandomized comparative studyTraditional schedulePatient experience measuresUnit admissionApgar scorePreterm birthBirth outcomesCare utilizationCochrane DatabaseBirth weightSTUDY SELECTIONTelevisits Compared With In-Person Visits for Routine Antenatal Care
Balk E, Danilack V, Cao W, Bhuma M, Adam G, Konnyu K, Peahl A. Televisits Compared With In-Person Visits for Routine Antenatal Care. Obstetrics And Gynecology 2023, 142: 19-29. PMID: 37290109, DOI: 10.1097/aog.0000000000005194.Peer-Reviewed Original ResearchConceptsRoutine antenatal careLow-strength evidenceAntenatal carePerson visitsPreterm birthNeonatal intensive care unit admissionIntensive care unit admissionRoutine antenatal care visitsCare unit admissionAntenatal care visitsHealth care utilizationNonrandomized comparative studyCoronavirus disease 2019 (COVID-19) pandemicDisease 2019 pandemicPrepandemic eraUnit admissionCare visitsCare utilizationClinical outcomesCochrane DatabaseVisit typeSTUDY SELECTIONTelevisitsHigh-income countriesPrimary study designRisk of Spontaneous Obstetric Anal Sphincter Injury Following Non-Operative Vaginal Delivery in a High-Risk Cohort.
Polnaszek B, Danilack V, Has P, Russo M, Hamel M, Tuuli M, Savitz D, Lewkowitz A. Risk of Spontaneous Obstetric Anal Sphincter Injury Following Non-Operative Vaginal Delivery in a High-Risk Cohort. Rhode Island Medical Journal 2023, 106: 43-44. PMID: 36848543, PMCID: PMC10408132.Peer-Reviewed Original ResearchChanges to Prenatal Care Visit Frequency and Telehealth
Konnyu K, Danilack V, Adam G, Peahl A, Cao W, Balk E. Changes to Prenatal Care Visit Frequency and Telehealth. Obstetrics And Gynecology 2023, 141: 299-323. PMID: 36649343, DOI: 10.1097/aog.0000000000005046.Peer-Reviewed Original ResearchConceptsRoutine prenatal careHealth care professionalsPrenatal careVisit scheduleTheoretical Domains FrameworkCare professionalsPrenatal care deliveryRoutine prenatal visitsHigh-risk pregnanciesGRADE-CERQual toolQuality of careCare visitsPrenatal visitQuantitative evidence synthesisCochrane DatabaseRoutine visitsClinic capacityTelevisitsSTUDY SELECTIONClinician's perspectiveCare modelPatientsPractice centerCare deliveryHealthcare Research
2022
Frailty as a predictor of delayed initiation of adjuvant chemotherapy in patients with ovarian cancer
Ramos S, Kulkarni A, Oliver M, Danilack V, Mathews C. Frailty as a predictor of delayed initiation of adjuvant chemotherapy in patients with ovarian cancer. International Journal Of Gynecological Cancer 2022, 33: 57-65. PMID: 36423959, DOI: 10.1136/ijgc-2022-003603.Peer-Reviewed Original ResearchConceptsInitiation of chemotherapyHigh-frailty groupModified Frailty IndexFrailty groupOvarian cancerFrailty scoreMFI scoreHigher mFI scoresPatients 18 yearsRetrospective cohort studyHigh-risk patientsTertiary medical centerElectronic medical recordsAdjuvant chemotherapyChemotherapy initiationFrail groupNeoadjuvant chemotherapyCohort studyOverall survivalFrailty indexPreoperative counselingModerate frailtyFunctional statusMedical recordsMedical CenterRisk factors for respiratory distress syndrome among high-risk early-term and full-term deliveries
Gould A, Ding J, Recabo O, Has P, Savitz D, Danilack V, Lewkowitz A. Risk factors for respiratory distress syndrome among high-risk early-term and full-term deliveries. The Journal Of Maternal-Fetal & Neonatal Medicine 2022, 35: 10401-10405. PMID: 36210090, PMCID: PMC9851950, DOI: 10.1080/14767058.2022.2128657.Peer-Reviewed Original ResearchConceptsRespiratory distress syndromeFetal growth restrictionEarly term infantsPresence of meconiumFull-term neonatesNovel risk factorsStrong risk factorRisk factorsHypertensive disordersMaternal demographicsCesarean deliveryDistress syndromeGestational ageIncidence of RDSSecondary analysisTertiary care obstetric hospitalRetrospective cohort studyLower gestational ageFull-term birthFull-term deliveryInfant health outcomesComorbid diabetesInfectious comorbiditiesIntrauterine inflammationSevere preeclampsiaDevelopment and Internal Validation of a Risk Prediction Model for Acute Cardiovascular Morbidity in Preeclampsia
Malhamé I, Raker C, Hardy E, Spalding H, Bouvier B, Hurlburt H, Vrees R, Daskalopoulou S, Nerenberg K, Savitz D, Mehta N, Danilack V. Development and Internal Validation of a Risk Prediction Model for Acute Cardiovascular Morbidity in Preeclampsia. Canadian Journal Of Cardiology 2022, 38: 1591-1599. PMID: 35709932, DOI: 10.1016/j.cjca.2022.05.007.Peer-Reviewed Original ResearchConceptsAdverse cardiovascular outcomesCardiovascular morbidityCardiovascular outcomesInternal validationAcute heart failurePrevious caesarean deliveryPrimary composite outcomeRisk prediction toolsEarly postpartum periodRisk prediction modelShort-term riskRisk assessment toolCaesarean deliveryCardiogenic shockSevere hypertensionComposite outcomeHeart failureGestational ageCerebrovascular disordersObstetric hospitalMaternal ageMyocardial infarctionPostpartum periodVentricular fibrillationPreeclampsiaOxytocin utilization for women undergoing an induction of labor by 1 kg/m2 increase in body mass index
Polnaszek B, Reilly J, Raker C, Lewkowitz A, Danilack V. Oxytocin utilization for women undergoing an induction of labor by 1 kg/m2 increase in body mass index. American Journal Of Obstetrics And Gynecology 2022, 227: 546-547. PMID: 35671778, PMCID: PMC10308358, DOI: 10.1016/j.ajog.2022.05.070.Peer-Reviewed Original Research
2021
Health Outcomes Associated With Clinician-initiated Delivery for Hypertensive Disorders at 34–38 Weeks’ Gestation
Savitz D, Danilack V, Cochancela J, Hughes B, Rouse D, Gutmann R. Health Outcomes Associated With Clinician-initiated Delivery for Hypertensive Disorders at 34–38 Weeks’ Gestation. Epidemiology 2021, 33: 260-268. PMID: 34799472, PMCID: PMC8810678, DOI: 10.1097/ede.0000000000001442.Peer-Reviewed Original ResearchConceptsHypertensive disordersWeeks' gestationInfant outcomesInfant HospitalWeek 34Week 37Week 35Neonatal intensive care unit admissionIntensive care unit admissionRecords-based cohort studyAdverse infant outcomesCare unit admissionRisk of progressionInfant health outcomesHealth Outcomes AssociatedGestational hypertensionNonsevere preeclampsiaUnit admissionHypertensive pregnanciesMaternal outcomesCohort studyGestational weeksAdverse outcomesLate pregnancySevere diseasePrediction Model Assessing Risk of Delivery after Diagnosis of Abnormal Umbilical Artery Doppler
Yu H, Has P, Danilack V, Werner E, Rouse D. Prediction Model Assessing Risk of Delivery after Diagnosis of Abnormal Umbilical Artery Doppler. American Journal Of Perinatology 2021, 40: 1253-1258. PMID: 34450676, DOI: 10.1055/s-0041-1735222.Peer-Reviewed Original ResearchConceptsFetal growth restrictionRisk of deliveryAntenatal corticosteroidsAbnormal UADAbnormal umbilical artery DopplerInitial eligibilityBackward stepwise logistic regressionDoppler velocimetry abnormalitiesInternal validationPre-pregnancy BMIReferral center studyUmbilical artery DopplerPrediction of deliveryRisk stratification methodsStepwise logistic regressionAntepartum managementArtery DopplerNeonatal morbiditySingleton pregnanciesCenter studyMedian GAGrowth restrictionMultivariable modelPatientsClinical aidThe independent and combined influences of small for gestational age and socioeconomic status on newborn metabolite levels
McCarthy M, Oltman S, Rogers E, Ryckman K, Jelliffe-Pawlowski L, Danilack V. The independent and combined influences of small for gestational age and socioeconomic status on newborn metabolite levels. The Journal Of Maternal-Fetal & Neonatal Medicine 2021, 35: 6192-6198. PMID: 33882790, DOI: 10.1080/14767058.2021.1909562.Peer-Reviewed Original ResearchConceptsSocioeconomic statusGestational ageMetabolite levelsHospital discharge dataDose-response relationshipEffect of SESNewborn interventionsSGA infantsSGA statusRetrospective cohortSmall birthweightFree carnitineBetter outcomesSGAMajority of metabolitesNutritional Assistance ProgramCalifornia infantsInfant's levelInfantsSelect metabolitesMedical insuranceAge exhibitIndependent effectsBirthweightEducation level
2020
Cardiovascular severe maternal morbidity in pregnant and postpartum women: development and internal validation of risk prediction models
Malhamé I, Danilack V, Raker C, Hardy E, Spalding H, Bouvier B, Hurlburt H, Vrees R, Savitz D, Mehta N. Cardiovascular severe maternal morbidity in pregnant and postpartum women: development and internal validation of risk prediction models. BJOG An International Journal Of Obstetrics & Gynaecology 2020, 128: 922-932. PMID: 32946639, DOI: 10.1111/1471-0528.16512.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityMaternal morbidityRisk prediction modelDelivery hospitalisationChronic hypertensionGestational hypertensionMaternal ageInternal validationPostpartum modelNon-Hispanic black race/ethnicityBlack race/ethnicityObstetric teaching hospitalAcute heart failureRetrospective cohort studyPoor pregnancy outcomesValvular heart diseaseStrongest predictorRace/ethnicityRisk assessment toolCardiogenic shockSevere hypertensionCohort studyMultiple gestationsPregnancy outcomesHeart failureOutpatient Opioid Use After Cesarean Delivery.
Emerson J, Danilack V, Kulkarni A, Kesselring C, Brousseau E, Matteson K. Outpatient Opioid Use After Cesarean Delivery. Rhode Island Medical Journal 2020, 103: 68-74. PMID: 32752572.Peer-Reviewed Original ResearchConceptsMorphine equivalent dosesCesarean deliveryOpioid needsOpioid useOpioid prescribingOutpatient opioid prescribingOutpatient opioid useAvailability of opioidsPatient-specific factorsOpioid patientsPrescribe opioidsClinical characteristicsPatient characteristicsPsychiatric comorbidityMedical recordsOpioid abuseOpiate useInpatient needsOpioidsEquivalent dosesLimited dataPearson correlation coefficientPrescribingPatientsT-testTerm Labor Induction and Cesarean Delivery Risk among Obese Women with and without Comorbidities
Glazer K, Danilack V, Field A, Werner E, Savitz D. Term Labor Induction and Cesarean Delivery Risk among Obese Women with and without Comorbidities. American Journal Of Perinatology 2020, 39: 154-164. PMID: 32722823, DOI: 10.1055/s-0040-1714422.Peer-Reviewed Original ResearchConceptsCesarean delivery riskLow-risk nulliparous womenPrior vaginal deliveryCesarean riskCesarean deliveryLabor inductionElective inductionNulliparous womenVaginal deliveryWeeks' gestationMaternal ageTerm inductionEarly term inductionTerm labor inductionPrior cesarean deliveryAdjusted risk ratioBody mass indexElective labor inductionWeeks of gestationDelivery riskRisk reductionARRIVE trialExpectant managementHypertensive disordersObstetric populationPrediction Model for Vaginal Birth After Induction of Labor in Women With Hypertensive Disorders of Pregnancy.
Beninati M, Ramos S, Danilack V, Has P, Savitz D, Werner E. Prediction Model for Vaginal Birth After Induction of Labor in Women With Hypertensive Disorders of Pregnancy. Obstetrics And Gynecology 2020, 136: 402-410. PMID: 32649502, DOI: 10.1097/aog.0000000000003938.Peer-Reviewed Original ResearchConceptsInduction of laborCesarean deliveryHypertensive disordersVaginal deliveryHosmer-Lemeshow testLabor inductionIntrapartum magnesium sulfateStepwise backward logistic regressionVaginal delivery successPrior cesarean deliveryBody mass indexPrelabor cesarean deliveryWeeks of gestationBackward logistic regressionFuture external validationSimilar discriminatory abilitySeizure prophylaxisCervical ripeningRetrospective cohortSingleton pregnanciesSpontaneous laborGestational ageMass indexStudy cohortVaginal birthPrecision of gestational age for prenatal medication use studies
Danilack V, Ananth C. Precision of gestational age for prenatal medication use studies. Paediatric And Perinatal Epidemiology 2020, 34: 607-608. PMID: 32163183, DOI: 10.1111/ppe.12670.Commentaries, Editorials and LettersIdentifying cardiovascular severe maternal morbidity in epidemiologic studies
Malhamé I, Mehta N, Raker C, Hardy E, Spalding H, Bouvier B, Savitz D, Danilack V. Identifying cardiovascular severe maternal morbidity in epidemiologic studies. Paediatric And Perinatal Epidemiology 2020, 34: 452-459. PMID: 31971615, DOI: 10.1111/ppe.12571.Peer-Reviewed Original ResearchMeSH KeywordsAdultDelivery, ObstetricElectric CountershockEpidemiologic StudiesFemaleHeart ArrestHospitalizationHumansInternational Classification of DiseasesMaternal MortalityOutcome Assessment, Health CarePre-EclampsiaPregnancyPregnancy Complications, CardiovascularPregnancy, High-RiskSensitivity and SpecificitySeverity of Illness IndexConceptsSevere maternal morbidityMaternal morbiditySevere preeclampsiaEpidemiologic studiesICD codesDelivery hospitalisationPredictive valueObstetric teaching hospitalAcute myocardial infarctionNegative predictive valuePositive predictive valueRandom sampleComposite variableCardiac arrestMaternal mortalityMyocardial infarctionTeaching hospitalAdministrative data setsHigh riskHospitalisationPreeclampsiaDisease controlMorbidityExpert cliniciansStandardised toolsElucidating the role of overweight and obesity in racial and ethnic disparities in cesarean delivery risk
Glazer K, Danilack V, Werner E, Field A, Savitz D. Elucidating the role of overweight and obesity in racial and ethnic disparities in cesarean delivery risk. Annals Of Epidemiology 2020, 42: 4-11.e4. PMID: 32005568, DOI: 10.1016/j.annepidem.2019.12.012.Peer-Reviewed Original ResearchConceptsBody mass indexCesarean delivery riskPopulation attributable fractionAttributable fractionHispanic womenPreconception weight managementRole of overweightLow-risk pregnanciesDelivery riskCesarean riskNulliparous birthsPerinatal disparitiesPrepregnancy overweightGestational complicationsDelivery hospitalMass indexRisk ratioWeight managementHigh prevalenceAdditional adjustmentRisk differenceClinical approachOverweightObesityEthnic disparities