2019
Flexibility sustains epithelial tissue homeostasis
Tai K, Cockburn K, Greco V. Flexibility sustains epithelial tissue homeostasis. Current Opinion In Cell Biology 2019, 60: 84-91. PMID: 31153058, PMCID: PMC6756930, DOI: 10.1016/j.ceb.2019.04.009.Peer-Reviewed Original ResearchConceptsEpithelial homeostasisEpithelial tissue homeostasisLive-imaging techniquesEpithelial cell interactionsIndividual epithelial cellsOrganism's lifetimeTissue homeostasisCell plasticityCell biologyMolecular mechanismsPathological settingsCell interactionsHomeostasisEpithelial cellsRecent advancesGeneticsBiologyMutationsImportant implicationsEpitheliumMechanismPlasticityCells
2018
Flexible fate determination ensures robust differentiation in the hair follicle
Xin T, Gonzalez D, Rompolas P, Greco V. Flexible fate determination ensures robust differentiation in the hair follicle. Nature Cell Biology 2018, 20: 1361-1369. PMID: 30420661, PMCID: PMC6314017, DOI: 10.1038/s41556-018-0232-y.Peer-Reviewed Original ResearchConceptsSingle-cell levelStem cellsStem cell differentiationGerm stem cellsTissue architectureMultiple cell typesFate determinationDetermination mechanismTissue homeostasisSame stem cellsCommon progenitorDifferentiation outcomesDifferentiation stimuliDifferentiation lineageCell differentiationCell typesNormal differentiationWnt activationHair folliclesUnanticipated flexibilityDifferentiationRobust differentiationProgenitorsCellsUninjured condition
2016
Hardwiring Stem Cell Communication through Tissue Structure
Xin T, Greco V, Myung P. Hardwiring Stem Cell Communication through Tissue Structure. Cell 2016, 164: 1212-1225. PMID: 26967287, PMCID: PMC4805424, DOI: 10.1016/j.cell.2016.02.041.Peer-Reviewed Original Research
2015
The Dynamic Duo: Niche/Stem Cell Interdependency
Mesa KR, Rompolas P, Greco V. The Dynamic Duo: Niche/Stem Cell Interdependency. Stem Cell Reports 2015, 4: 961-966. PMID: 26028534, PMCID: PMC4471832, DOI: 10.1016/j.stemcr.2015.05.001.Peer-Reviewed Original ResearchConceptsNormal tissue homeostasisStem cell behaviorStem cell interactionsTissue homeostasisCellular turnoverPathological settingsCell behaviorStem cellsMost tissuesFundamental processesDynamic duoCell interactionsModel systemNew cellsCell productionTissue regenerationCellsTissueLive miceOrganismsHomeostasisTremendous advancesImaging approachNovel imaging approachBasic understanding