2023
Organ function is preserved despite reorganization of niche architecture in the hair follicle
Wei H, Du S, Parksong J, Pasolli H, Matte-Martone C, Regot S, Gonzalez L, Xin T, Greco V. Organ function is preserved despite reorganization of niche architecture in the hair follicle. Cell Stem Cell 2023, 30: 962-972.e6. PMID: 37419106, PMCID: PMC10362479, DOI: 10.1016/j.stem.2023.06.003.Peer-Reviewed Original ResearchConceptsNiche architectureDermal papilla fibroblastsDifferentiated lineagesHair follicle growthStereotypic architectureMultipotent progenitorsEpithelial progenitorsFunctional importanceNicheStem cellsFibroblast nicheProgenitorsPowerful modelIntravital imagingDermal papillaFibroblastsHair folliclesFollicle growthOrgan functionLineagesDifferentiationCrosstalkHairProliferationCells
2013
Spatial organization within a niche as a determinant of stem-cell fate
Rompolas P, Mesa KR, Greco V. Spatial organization within a niche as a determinant of stem-cell fate. Nature 2013, 502: 513-518. PMID: 24097351, PMCID: PMC3895444, DOI: 10.1038/nature12602.Peer-Reviewed Original ResearchConceptsStem cell fateHair follicle nicheStem cell lineagesStem cellsStem cell nicheHair follicle stem cellsStem cell compartmentFollicle stem cellsFate determinationGenetic lineagesDifferentiated fateAdult tissuesNiche locationsMammalian tissuesNicheHair regenerationLineagesSpatial organizationEpithelial cellsFateCellsHair growthRegenerationLive miceTissue