2024
Regional European genetic ancestry predicts type I interferon level and risk of severe viral infection
Nln I, Shum J, Ghodke-Puranik Y, Tipon R, Triese D, Amin S, Makol A, Osborn T, Chowdhary V, Thanarajasingam U, Muskardin T, Oke V, Gunnarsson I, Zickert A, Zervou M, Boumpas D, Svenungsson E, Goulielmos G, Niewold T. Regional European genetic ancestry predicts type I interferon level and risk of severe viral infection. QJM 2024, 117: 581-588. PMID: 38530799, PMCID: PMC11389909, DOI: 10.1093/qjmed/hcae052.Peer-Reviewed Original ResearchType I IFN levelsViral infection outcomesI interferonLupus patientsEuropean genetic ancestryInfection outcomesAnti-viral cytokinesSevere viral infectionsType I interferon levelsHost genetic factorsRisk of severe viral infectionsSevere organ failureI interferon levelsType I IFNType I interferonVirus prior to infectionViral hepatitisOrgan failureGenetic testingViral infectionI IFNOutcome dataHost defenseGenetic factorsGenetic ancestry
2008
Liver Involvement in Systemic Lupus Erythematosus: Case Review of 40 Patients
Chowdhary VR, Crowson CS, Poterucha JJ, Moder KG. Liver Involvement in Systemic Lupus Erythematosus: Case Review of 40 Patients. The Journal Of Rheumatology 2008, 35: 2159-2164. PMID: 18793002, DOI: 10.3899/jrheum.080336.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusEndstage liver diseaseLiver diseasePortal hypertensionLiver involvementViral hepatitisLupus erythematosusLiver disease-free survivalNonalcoholic fatty liver diseaseCoexistent liver diseaseSubclinical liver involvementDevelopment of cirrhosisLiver enzyme abnormalitiesAlanine aminotransferase levelsDisease-free survivalRetrospective chart reviewCohort of patientsFatty liver diseasePrimary biliary cirrhosisAlkaline phosphatase levelsClinical diagnostic groupsAutoimmune hepatitisCryptogenic cirrhosisHepatitis CAminotransferase levels