2013
Karyotype Versus Microarray Testing for Genetic Abnormalities After Stillbirth
Reddy U, Page G, Saade G, Silver R, Thorsten V, Parker C, Pinar H, Willinger M, Stoll B, Heim-Hall J, Varner M, Goldenberg R, Bukowski R, Wapner R, Drews-Botsch C, O’Brien B, Dudley D, Levy B. Karyotype Versus Microarray Testing for Genetic Abnormalities After Stillbirth. Obstetrical & Gynecological Survey 2013, 68: 278-280. DOI: 10.1097/01.ogx.0000429295.65513.69.Peer-Reviewed Original ResearchMicroarray analysisUnknown significancePathogenic variantsAntepartum stillbirthPostmortem examinationKaryotype analysisMore abnormalitiesPlacental tissueMicroarray resultsStillbirth Collaborative Research NetworkBenign variantsMicroarray testingPopulation-based studyGenomic abnormalitiesGeographic catchment areaStandard karyotype analysisCopy number variantsCord bloodClinical significanceNonviable tissueClinical relevanceStillbirthAbnormal karyotypeClinical implicationsFetal tissues
2012
Karyotype versus Microarray Testing for Genetic Abnormalities after Stillbirth
Reddy UM, Page GP, Saade GR, Silver RM, Thorsten VR, Parker CB, Pinar H, Willinger M, Stoll BJ, Heim-Hall J, Varner MW, Goldenberg RL, Bukowski R, Wapner RJ, Drews-Botsch CD, O'Brien BM, Dudley DJ, Levy B. Karyotype versus Microarray Testing for Genetic Abnormalities after Stillbirth. New England Journal Of Medicine 2012, 367: 2185-2193. PMID: 23215556, PMCID: PMC4295117, DOI: 10.1056/nejmoa1201569.Peer-Reviewed Original ResearchConceptsGenetic abnormalitiesAntepartum stillbirthCongenital anomaliesMicroarray analysisStillbirth Collaborative Research NetworkCopy number variantsAnalysis of stillbirthPopulation-based studyKaryotype analysisResults of karyotypeGeographic catchment areaSingle nucleotide polymorphism arrayClinical significancePostmortem examinationNonviable tissueStillbirthTrue prevalenceFetal tissuesUnaffected personsAbnormalitiesKaryotype resultsMicroarray testingCollaborative research networksGenetic diagnosisPolymorphism array