Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING
Holm CK, Jensen SB, Jakobsen MR, Cheshenko N, Horan KA, Moeller HB, Gonzalez-Dosal R, Rasmussen SB, Christensen MH, Yarovinsky TO, Rixon FJ, Herold BC, Fitzgerald KA, Paludan SR. Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING. Nature Immunology 2012, 13: 737-743. PMID: 22706339, PMCID: PMC3411909, DOI: 10.1038/ni.2350.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell FusionChemokine CXCL10HEK293 CellsHeLa CellsHerpesvirus 1, HumanHumansImmunity, InnateInterferon Type ILeukocytesLymphocyte ActivationMacrophagesMembrane FusionMembrane GlycoproteinsMembrane ProteinsMiceMice, KnockoutMyeloid Differentiation Factor 88Signal TransductionToll-Like Receptor 7Toll-Like Receptor 9Virus InternalizationConceptsAdaptor STINGInnate immune responseImmune responseVirus-cell fusionViral infectionInnate immunityEarly eventsStings