Interferons Increase Cell Resistance to Staphylococcal Alpha-Toxin
Yarovinsky TO, Monick MM, Husmann M, Hunninghake GW. Interferons Increase Cell Resistance to Staphylococcal Alpha-Toxin. Infection And Immunity 2007, 76: 571-577. PMID: 18070901, PMCID: PMC2223481, DOI: 10.1128/iai.01088-07.Peer-Reviewed Original ResearchConceptsStaphylococcal infectionsIFN-alphaTumor necrosis factor alphaNecrosis factor alphaStaphylococcal alpha toxinFatty acid synthase activityCell resistancePore-forming toxinsProinflammatory mediatorsIL-6IL-4Factor alphaInterleukin-1betaIFN-gammaImportant virulence factorAlpha toxinDepletion of ATPIFN-betaProtective roleLipid metabolismMitogen-activated protein kinaseCaspase-1InterferonHost factorsPrior exposure