2024
Effect of endoscopic ultrasound guided celiac plexus block on the palliation of pain in chronic pancreatitis (EPOCH Trial): study protocol for a randomized multicenter sham-controlled trial {1}
Wilcox C, Bang J, Buxbaum J, Gardner T, Hawes R, Kedia P, Mardini S, Muniraj T, Navaneethan U, Oza V, Tarnasky P, Thakkar S, Waxman I, Varadarajulu S. Effect of endoscopic ultrasound guided celiac plexus block on the palliation of pain in chronic pancreatitis (EPOCH Trial): study protocol for a randomized multicenter sham-controlled trial {1}. Trials 2024, 25: 676. PMID: 39396987, PMCID: PMC11472533, DOI: 10.1186/s13063-024-08478-y.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal PainAutonomic Nerve BlockCeliac PlexusEndosonographyHumansMulticenter Studies as TopicNerve BlockPain MeasurementPalliative CarePancreatitis, ChronicProspective StudiesRandomized Controlled Trials as TopicTime FactorsTreatment OutcomeUltrasonography, InterventionalUnited StatesConceptsCeliac plexus blockAbdominal painChronic pancreatitisVisual analog scalePlexus blockSham-controlled trialRandomized sham-controlled trialEndoscopic ultrasound-guided celiac plexus blockEffectiveness of endoscopic ultrasoundBrief Pain Inventory Short FormDocumented chronic pancreatitisPainful chronic pancreatitisPalliation of painTime of EUSTreatment of abdominal painPain scoresBPI-SFSteroid combinationsAnalog scaleEndoscopic ultrasoundProspective studyCeliac plexusRandomized trialsShort formPancreatitisSMART Medical Review: Acute Pancreatitis Assessment and Management in the First 24 Hours
Lee P, Bishu S, Breze C, Chak A, Gardner T, Guda N, Kaul V, Muniraj T, Papachristou G, Schrope B, Spagnolo D, Strand D, Tarnasky P, Taylor J, Wilcox C, Whitcomb D. SMART Medical Review: Acute Pancreatitis Assessment and Management in the First 24 Hours. 2024, 1: e19-e48. DOI: 10.69734/7dcnna53.Peer-Reviewed Original ResearchPoint of careManagement of APClinical decision support toolQuality of careQuality improvement recommendationsGroup of clinical expertsAcute pancreatitisInnate inflammatory responseCareClinical expertsExpert recommendationsLife-threatening consequencesDecision support toolEarly treatmentPhysical examinationInflammatory responseInflammatory reactionRecommendationsSeveral determinantsIndividualized treatmentImprovement recommendationsSupport toolDiagnosisLaboratory testsTreatment
2023
Clinical predictive value of renalase in post-ERCP pancreatitis
Muniraj T, Desir G, Gorelick F, Guo X, Ciarleglio M, Deng Y, Jamidar P, Farrell J, Aslanian H, Laine L. Clinical predictive value of renalase in post-ERCP pancreatitis. Gastrointestinal Endoscopy 2023, 99: 822-825.e1. PMID: 38103747, DOI: 10.1016/j.gie.2023.12.020.Peer-Reviewed Original ResearchPost-ERCP pancreatitisRenalase levelsPlasma renalase levelsProspective cohort studyPotential clinical roleAcute experimental pancreatitisLongitudinal regression modelsPEP patientsPlasma renalaseCohort studyTertiary hospitalClinical roleExperimental pancreatitisRenalaseAbstractTextERCPPancreatitisFurther studiesAIMSRegression modelsOutcomes of cold snare EMR of nonampullary duodenal adenomas ≥1 cm: a multicenter study
Wilson N, Abdallah M, Schulman A, Mosko J, Saeed A, Kothari S, Kaul V, Kothari T, Phan J, Kumar A, Tofani C, Kim R, Westanmo A, Moy B, Dang F, Canakis A, Sharma N, Muniraj T, Azeem N, Bilal M. Outcomes of cold snare EMR of nonampullary duodenal adenomas ≥1 cm: a multicenter study. Gastrointestinal Endoscopy 2023, 99: 971-980.e1. PMID: 38092125, DOI: 10.1016/j.gie.2023.12.007.Peer-Reviewed Original ResearchNonampullary duodenal adenomasEndoscopic mucosal resectionCold snare endoscopic mucosal resectionSnare endoscopic mucosal resectionDuodenal adenomasUse of electrocauteryAdverse eventsMucosal resectionMulticenter studyUnderwater endoscopic mucosal resectionLarge duodenal adenomasMulticenter retrospective studyRetrospective multicenter studyPredictors of recurrenceAcceptable recurrence rateHigh-grade dysplasiaFuture prospective studiesCases of perforationAdenoma rateSecondary outcomesImmediate bleedingPrimary outcomeRecurrent adenomasIndependent predictorsProspective studyAdvancing surveillance protocols for dysplastic Barrett’s esophagus after complete remission of intestinal metaplasia: Time to rethink biopsy strategy?
Burton S, Muniraj T. Advancing surveillance protocols for dysplastic Barrett’s esophagus after complete remission of intestinal metaplasia: Time to rethink biopsy strategy? Gastrointestinal Endoscopy 2023, 98: 733-734. PMID: 37863568, DOI: 10.1016/j.gie.2023.07.051.Peer-Reviewed Original ResearchImproving Pancreatic Cyst Management: Artificial Intelligence-Powered Prediction of Advanced Neoplasms through Endoscopic Ultrasound-Guided Confocal Endomicroscopy
Jiang J, Chao W, Cao T, Culp S, Napoléon B, El-Dika S, Machicado J, Pannala R, Mok S, Luthra A, Akshintala V, Muniraj T, Krishna S. Improving Pancreatic Cyst Management: Artificial Intelligence-Powered Prediction of Advanced Neoplasms through Endoscopic Ultrasound-Guided Confocal Endomicroscopy. Biomimetics 2023, 8: 496. PMID: 37887627, PMCID: PMC10604893, DOI: 10.3390/biomimetics8060496.Peer-Reviewed Original ResearchS11 Cholecystectomy Reduces the Odds of Inpatient Mortality in Patients With Acute Biliary Pancreatitis
Restrepo D, Doshi R, Nawaz A, Chaar A, Kothari T, Laine L, Muniraj T. S11 Cholecystectomy Reduces the Odds of Inpatient Mortality in Patients With Acute Biliary Pancreatitis. The American Journal Of Gastroenterology 2023, 118: s9-s10. DOI: 10.14309/01.ajg.0000949684.33264.0a.Peer-Reviewed Original ResearchS3383 A Rare Case of Hemobilia Secondary to Choledochal Varices in a Patient With Chronic Schistosomiasis
White M, Mezzacappa C, Hass D, Schlachter T, Muniraj T. S3383 A Rare Case of Hemobilia Secondary to Choledochal Varices in a Patient With Chronic Schistosomiasis. The American Journal Of Gastroenterology 2023, 118: s2238-s2239. DOI: 10.14309/01.ajg.0000963172.06896.9d.Peer-Reviewed Original ResearchEndoscopic Ultrasound in Cancer Staging
Aslanian H, Muniraj T, Nagar A, Parsons D. Endoscopic Ultrasound in Cancer Staging. Gastrointestinal Endoscopy Clinics Of North America 2023, 34: 37-49. PMID: 37973230, DOI: 10.1016/j.giec.2023.09.009.Peer-Reviewed Original ResearchSpontaneous Hyperinflation of Gastric Weight Loss Balloon
Mathialagan K, Parsons D, Muniraj T. Spontaneous Hyperinflation of Gastric Weight Loss Balloon. Digestive Diseases And Sciences 2023, 68: 4067-4068. PMID: 37676629, DOI: 10.1007/s10620-023-08092-z.Peer-Reviewed Original ResearchEUS-guided Gastroenterostomy
Kahaleh M, Tyberg A, Sameera S, Sarkar A, Shahid H, Abdelqader A, Gjeorgjievski M, Gaidhane M, Muniraj T, Jamidar P, Aslanian H, Abraham M, Lajin M, Kedia P, Nieto J, Parsa N, Andalib I, Bashir M, Kowalski T, Loren D, Kumar A, Schlachterman A, Chiang A, Holmes I, Ladd A, Oleas R, Zolotarevsky E, Robles-Medranda C, Barthet M. EUS-guided Gastroenterostomy. Journal Of Clinical Gastroenterology 2023, 58: 570-573. PMID: 37646532, DOI: 10.1097/mcg.0000000000001903.Peer-Reviewed Original ResearchEUS-GEAdverse eventsMalignant diseaseClinical successSelf-expanding metal stent placementLimited long-term efficacyGastric outlet obstructionTertiary care centerLong-term outcomesLong-term efficacyMetal stent placementAverage procedure timeProcedure-related informationHospitalization admissionsRetrospective registryHospital lengthMalignant indicationsOutlet obstructionSecondary outcomesSurgical bypassUnderlying diseaseConsecutive patientsPrimary outcomeBenign etiologyEtiology groupsSerial serum lipase testing after the initial diagnostic workup for inpatients with acute pancreatitis: What is the evidence?
Magier S, Muniraj T, Merchant N. Serial serum lipase testing after the initial diagnostic workup for inpatients with acute pancreatitis: What is the evidence? Cleveland Clinic Journal Of Medicine 2023, 90: 341-343. PMID: 37263664, DOI: 10.3949/ccjm.90a.22060.Peer-Reviewed Original ResearchSu1920 IMPACT OF OBESITY AND MORBID OBESITY ON OUTCOMES OF PATIENTS UNDERGOING ENDOSCOPIC PANCREATIC NECRESECTOMY
Nawaz A, Chaar A, Rizwan R, Fetene J, Restrepo D, Alchirazi K, Abdulkarim D, Khalid F, Mathialagan K, Cheung M, Laine L, Muniraj T. Su1920 IMPACT OF OBESITY AND MORBID OBESITY ON OUTCOMES OF PATIENTS UNDERGOING ENDOSCOPIC PANCREATIC NECRESECTOMY. Gastroenterology 2023, 164: s-714. DOI: 10.1016/s0016-5085(23)02660-4.Peer-Reviewed Original ResearchSa1420 FRAILTY IS ASSOCIATED WITH POOR OUTCOMES IN PATIENTS ADMITTED FOR ACUTE NECROTIZING PANCREATITIS
Nawaz A, Chaar A, Rizwan R, Restrepo D, Fetene J, Alchirazi K, Abdulkarim D, Khalid F, Doshi R, Mathialagan K, Hung K, Laine L, Muniraj T. Sa1420 FRAILTY IS ASSOCIATED WITH POOR OUTCOMES IN PATIENTS ADMITTED FOR ACUTE NECROTIZING PANCREATITIS. Gastroenterology 2023, 164: s-390. DOI: 10.1016/s0016-5085(23)01905-4.Peer-Reviewed Original ResearchSa1408 PREDICTIVE VALUE OF RENALASE IN POST-ERCP PANCREATITIS
Muniraj T, Desir G, Gorelick F, Guo X, Ciarleglio M, Deng Y, Jamidar P, Farrell J, Aslanian H, Laine L. Sa1408 PREDICTIVE VALUE OF RENALASE IN POST-ERCP PANCREATITIS. Gastroenterology 2023, 164: s-384-s-385. DOI: 10.1016/s0016-5085(23)01894-2.Peer-Reviewed Original Research
2022
Acute pancreatitis precedes chronic pancreatitis in the majority of patients: Results from the NAPS2 consortium
Singh V, Whitcomb D, Banks P, AlKaade S, Anderson M, Amann S, Brand R, Conwell D, Cote G, Gardner T, Gelrud A, Guda N, Forsmark C, Lewis M, Sherman S, Muniraj T, Romagnuolo J, Tan X, Tang G, Sandhu B, Slivka A, Wilcox C, Yadav D, Wilcox C, Guda N, Banks P, Conwell D, Lo S, Gelrud A, Gardner T, Baillie J, Forsmark C, Muniraj T, Sherman S, Singh V, Lewis M, Romagnuolo J, Hawes R, Cote G, Lawrence C, Anderson M, Amann S, Etemad B, DeMeo M, Kochman M, Abberbock J, Barmada M, Bauer E, Brand R, Kennard E, LaRusch J, O'Connell M, Stello K, Slivka A, Talluri J, Tang G, Whitcomb D, Wisniewski S, Yadav D, Burton F, AlKaade S, DiSario J, Sandhu B, Money M, Steinberg W. Acute pancreatitis precedes chronic pancreatitis in the majority of patients: Results from the NAPS2 consortium. Pancreatology 2022, 22: 1091-1098. PMID: 36404201, PMCID: PMC10122210, DOI: 10.1016/j.pan.2022.10.004.Peer-Reviewed Original ResearchConceptsDiagnosis of CPAcute pancreatitisChronic pancreatitisCP diagnosisAP patientsAssociation of APNorth American Pancreatitis StudiesMajority of patientsMultivariable logistic regressionDisease-related factorsNorth American cohortClinical acute pancreatitisAP episodeAbdominal painSecondary preventionMultivariable analysisExocrine insufficiencyPancreatic atrophyMore episodesUS CentersWhite raceLower oddsPatientsAmerican cohortPancreatitisEvaluation and Management of the Patient with a Pancreatic Cyst
Göktürk S, Muniraj T, Aslanian H. Evaluation and Management of the Patient with a Pancreatic Cyst. 2022, 415-430. DOI: 10.1007/978-3-030-41683-6_27.Peer-Reviewed Original ResearchPancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression
Fu D, Blobner B, Greer P, Lafyatis R, Bellin M, Whitcomb D, Study P, Bellin M, Beilman G, Study G, Brand R, Ohlsen C, Saloman J, Whitcomb D, Park H, Lee K, Paniccia A, Zureikat A, Group N, Alkaade S, Amann S, Anderson M, Banks P, Conwell D, Cote G, Forsmark C, Gardner T, Gelrud A, Guda N, Lewis M, Muniraj T, Papachristou G, Romagnuolo J, Sandhu B, Sherman S, Singh V, Slivka A, Wilcox C, Yadav D. Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression. Gastroenterology 2022, 164: 289-292.e4. PMID: 36191639, PMCID: PMC9892203, DOI: 10.1053/j.gastro.2022.09.036.Peer-Reviewed Original ResearchS1146 Impact of Frailty on ERCP Outcomes
Nawaz A, Chaar A, Rizwan R, Abdulkarim D, Khalid F, Muniraj T. S1146 Impact of Frailty on ERCP Outcomes. The American Journal Of Gastroenterology 2022, 117: e834-e835. DOI: 10.14309/01.ajg.0000861224.34232.7c.Peer-Reviewed Original ResearchS30 Serial Lipase Measurement Prolongs Hospitalization in Patients With Acute Pancreatitis
Magier S, Pascal M, Nawaz A, Muniraj T, Hung K. S30 Serial Lipase Measurement Prolongs Hospitalization in Patients With Acute Pancreatitis. The American Journal Of Gastroenterology 2022, 117: e23-e24. DOI: 10.14309/01.ajg.0000856760.09452.52.Peer-Reviewed Original Research