2022
Evaluating spatially adaptive guidelines for the treatment of gonorrhea to reduce the incidence of gonococcal infection and increase the effective lifespan of antibiotics
Yaesoubi R, Cohen T, Hsu K, Gift TL, St. Cyr SB, Salomon JA, Grad YH. Evaluating spatially adaptive guidelines for the treatment of gonorrhea to reduce the incidence of gonococcal infection and increase the effective lifespan of antibiotics. PLOS Computational Biology 2022, 18: e1009842. PMID: 35139073, PMCID: PMC8863219, DOI: 10.1371/journal.pcbi.1009842.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsGonorrheaHomosexuality, MaleHumansIncidenceLongevityMaleNeisseria gonorrhoeaeSexual and Gender MinoritiesConceptsIncidence of gonorrhoeaTreatment guidelinesResistance prevalenceGonorrhea casesTreatment of gonorrheaNational surveillance systemPrevalence of resistanceTransmission dynamic modelGonococcal infectionGonorrhea treatmentMSM populationAntibiotic susceptibilityGonorrheaStandardized guidelinesSurveillance dataPrevalenceIncidenceAntibioticsPotential strategySurveillance systemAbsence of pointsGuidelinesCurrent strategiesEffective lifespanMen
2020
Adaptive guidelines for the treatment of gonorrhea to increase the effective life span of antibiotics among men who have sex with men in the United States: A mathematical modeling study
Yaesoubi R, Cohen T, Hsu K, Gift TL, Chesson H, Salomon JA, Grad YH. Adaptive guidelines for the treatment of gonorrhea to increase the effective life span of antibiotics among men who have sex with men in the United States: A mathematical modeling study. PLOS Medicine 2020, 17: e1003077. PMID: 32243443, PMCID: PMC7122693, DOI: 10.1371/journal.pmed.1003077.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsGonorrheaHomosexuality, MaleHumansLongevityMaleModels, TheoreticalPractice Guidelines as TopicTreatment OutcomeUnited StatesConceptsFirst-line antibioticsPrevalence of resistanceMSM populationGonorrhea casesPrevalence of gonorrheaTreatment of gonorrheaTransmission of gonorrheaIncidence of gonorrhoeaGonococcal antimicrobial resistanceProportion of casesAlternative surveillance strategiesBurden of gonorrheaEffective surveillance systemTreatment guidelinesGonorrhea treatmentGonorrhoea transmissionClinical effectivenessOverall burdenSurveillance estimatesLife spanGonorrheaDrug susceptibilitySurveillance findingsSurveillance strategiesSurveillance program
2015
HIV burden in men who have sex with men: a prospective cohort study 2007–2012
Jia Z, Huang X, Wu H, Zhang T, Li N, Ding P, Sun Y, Liu Z, Wei F, Zhang H, Jiao Y, Ji Y, Zhang Y, Guo C, Li W, Mou D, Xia W, Li Z, Chen D, Yan H, Chen X, Zhao J, Meyers K, Cohen T, Mayer K, Salomon JA, Lu Z, Dye C. HIV burden in men who have sex with men: a prospective cohort study 2007–2012. Scientific Reports 2015, 5: 11205. PMID: 26135810, PMCID: PMC5393284, DOI: 10.1038/srep11205.Peer-Reviewed Original ResearchConceptsHIV infectionHIV-negative MSMProspective cohort studyHIV incidence ratesIntensive preventive interventionIncident HIVCohort studyHIV burdenHIV incidenceIncident casesRisk factorsIncidence rateEarly treatmentPrevalent casesChinese MSMHIVPreventive interventionsInfectionMSMFollowPerfect complianceMenEnrollmentSyphilisCohort