2024
The impact of COVID-19 national lockdowns on drug-resistant tuberculosis in KwaZulu-Natal, South Africa: A spatial analysis
Harrington K, Gandhi N, Shah N, Naidoo K, Auld S, Andrews J, Brust J, Lutchminarain K, Coe M, Willis F, Campbell A, Cohen T, Jenness S, Waller L, Investigators O. The impact of COVID-19 national lockdowns on drug-resistant tuberculosis in KwaZulu-Natal, South Africa: A spatial analysis. Annals Of Epidemiology 2024, 97: 44-51. PMID: 39038747, DOI: 10.1016/j.annepidem.2024.07.044.Peer-Reviewed Original ResearchKwaZulu-Natal ProvinceTB diagnosisDrug resistanceBayesian conditional autoregressive modelProspective cohort studyKwaZulu-NatalCOVID-19 national lockdownDrug-resistant tuberculosisRate of diagnosisCOVID-19 mitigation strategiesStatistics South AfricaSpatial analysisSpatial distributionMunicipal characteristicsCohort studyDR-TBNotification ratesTB notificationsSouth AfricaSurface mappingRate of casesRelative-riskCOVID-19Conditional autoregressive modelSpatial correlationQuantifying gaps in the tuberculosis care cascade in Brazil: A mathematical model study using national program data
Emani S, Alves K, Alves L, da Silva D, Oliveira P, Castro M, Cohen T, de Macedo Couto R, Sanchez M, Menzies N. Quantifying gaps in the tuberculosis care cascade in Brazil: A mathematical model study using national program data. PLOS Medicine 2024, 21: e1004361. PMID: 38512968, PMCID: PMC10994550, DOI: 10.1371/journal.pmed.1004361.Peer-Reviewed Original ResearchDisability-adjusted life yearsLoss to follow-upTreatment loss to follow-upCare cascadeHealth lossDelay to diagnosisTB diseaseTB diagnosisReduce delays to diagnosisHuman immunodeficiency virusContribution of social factorsTotal health system costsCare cascade outcomesTB care cascadeMortality Information SystemBurden of TB diseaseHealth system costsLifetime health outcomesNotifiable Diseases Information SystemBurden of diseaseIncident TB casesState of residenceNational program dataFollow-upHealth outcomes
2019
Disparities in access to diagnosis and care in Blantyre, Malawi, identified through enhanced tuberculosis surveillance and spatial analysis
MacPherson P, Khundi M, Nliwasa M, Choko AT, Phiri VK, Webb EL, Dodd PJ, Cohen T, Harris R, Corbett EL. Disparities in access to diagnosis and care in Blantyre, Malawi, identified through enhanced tuberculosis surveillance and spatial analysis. BMC Medicine 2019, 17: 21. PMID: 30691470, PMCID: PMC6350280, DOI: 10.1186/s12916-019-1260-6.Peer-Reviewed Original ResearchConceptsTB case notification ratesCase notification ratesCommunity health workersNotification ratesTB casesLow case detectionSingle sputum sampleInverse care lawArea-level factorsTB registrationTB clinicTB patientsClinical characteristicsTB diagnosisTuberculosis casesResultsIn totalTB surveillanceCase detectionModifiable predictorsSputum samplesHealth workersTB officersTB microscopyAdjusted modelTuberculosis surveillance