Models to understand the population-level impact of mixed strain M. tuberculosis infections
Sergeev R, Colijn C, Cohen T. Models to understand the population-level impact of mixed strain M. tuberculosis infections. Journal Of Theoretical Biology 2011, 280: 88-100. PMID: 21514304, PMCID: PMC3111980, DOI: 10.1016/j.jtbi.2011.04.011.Peer-Reviewed Original ResearchConceptsDrug-resistant strainsMixed strain infectionsStrain infectionDrug-sensitive tuberculosisDrug-resistant tuberculosisM. tuberculosis infectionLower basic reproductive numberDrug-resistant infectionsTuberculosis patientsTuberculosis infectionTreatment successDrug-resistant bacteriaFuture burdenLong-term effectsStrain-specific differencesDrug resistanceInfectionPopulation-level impactTuberculosisM. tuberculosisMixed infectionsMycobacterium tuberculosisBasic reproductive numberCo-infected hostsSmall subpopulation