2023
Transmission modeling to infer tuberculosis incidence prevalence and mortality in settings with generalized HIV epidemics
Dodd P, Shaweno D, Ku C, Glaziou P, Pretorius C, Hayes R, MacPherson P, Cohen T, Ayles H. Transmission modeling to infer tuberculosis incidence prevalence and mortality in settings with generalized HIV epidemics. Nature Communications 2023, 14: 1639. PMID: 36964130, PMCID: PMC10037365, DOI: 10.1038/s41467-023-37314-1.Peer-Reviewed Original ResearchConceptsHigh HIV prevalence settingsEstimation of burdenHIV prevalence settingsGeneralized HIV epidemicsTB transmission modelAntiretroviral therapyTB infectionTB incidenceHIV prevalenceTB prevalencePrevalence settingsTB epidemicHIV epidemicHigh burdenBurden estimatesNotification dataAnnual riskSingle pathogenIntervention impactTherapy effectsTuberculosisPrevalenceEpidemicBurdenAfrican countries
2020
Children as sentinels of tuberculosis transmission: disease mapping of programmatic data
Gunasekera KS, Zelner J, Becerra MC, Contreras C, Franke MF, Lecca L, Murray MB, Warren JL, Cohen T. Children as sentinels of tuberculosis transmission: disease mapping of programmatic data. BMC Medicine 2020, 18: 234. PMID: 32873309, PMCID: PMC7466499, DOI: 10.1186/s12916-020-01702-x.Peer-Reviewed Original ResearchConceptsNational Tuberculosis ProgrammeActive case-finding interventionsCase-finding interventionsTuberculosis transmissionNotification dataTuberculosis ProgrammeTuberculosis incidenceChild casesChildhood tuberculosis casesRecent transmission eventsProportion of casesCase notification dataMolecular epidemiological methodsMolecular epidemiologic methodsEndemic infectious diseasesTuberculosis casesProspective studyAdult casesDisease progressionNotification registerProgrammatic dataDistricts of LimaEpidemiological methodsInfectious diseasesTransmission hotspots