2021
The positive externalities of migrant-based TB control strategy in a Chinese urban population with internal migration: a transmission-dynamic modeling study
Yang C, Kang J, Lu L, Guo X, Shen X, Cohen T, Menzies NA. The positive externalities of migrant-based TB control strategy in a Chinese urban population with internal migration: a transmission-dynamic modeling study. BMC Medicine 2021, 19: 95. PMID: 33874940, PMCID: PMC8055441, DOI: 10.1186/s12916-021-01968-9.Peer-Reviewed Original ResearchConceptsTB casesTB incidenceNew TB casesTB control strategiesEpidemiology of tuberculosisMeaningful health benefitsChinese urban populationMolecular epidemiologic studiesTransmission dynamic modelSongjiang DistrictRecent infectionTB interventionsTB transmissionTB notificationsEpidemiological featuresPreventive treatmentActive screeningEpidemiologic studiesLatent infectionTB policyDemographic dataIndirect protectionTuberculosisEpidemiological driversLocal transmission
2018
Progression from latent infection to active disease in dynamic tuberculosis transmission models: a systematic review of the validity of modelling assumptions
Menzies NA, Wolf E, Connors D, Bellerose M, Sbarra AN, Cohen T, Hill AN, Yaesoubi R, Galer K, White PJ, Abubakar I, Salomon JA. Progression from latent infection to active disease in dynamic tuberculosis transmission models: a systematic review of the validity of modelling assumptions. The Lancet Infectious Diseases 2018, 18: e228-e238. PMID: 29653698, PMCID: PMC6070419, DOI: 10.1016/s1473-3099(18)30134-8.Peer-Reviewed Original ResearchConceptsTuberculosis transmission modelActive diseaseCumulative incidenceRisk factorsSystematic reviewNatural historyFeatures of epidemiologyDisease natural historyIndividual risk factorsTuberculosis natural historyEarliest available dateWeb of ScienceAnnual incidenceCochrane LibraryTuberculosis incidenceInclusion criteriaFuture tuberculosisLatent infectionInitial infectionIncidenceSubstantial proportionPopulation groupsAvailable dateInfectionDisease
2013
Evaluation of the Tuberculosis Strain Typing Service (TB-STS) in England
Mears J, Vynnycky E, Lord J, Borgdorff M, Cohen T, Abubakar I, Sonnenberg P, group O. Evaluation of the Tuberculosis Strain Typing Service (TB-STS) in England. The Lancet 2013, 382: s73. DOI: 10.1016/s0140-6736(13)62498-8.Peer-Reviewed Original ResearchTuberculosis incidenceProportion of infectionsDiagnostic delayBase-case assumptionsLatent infectionPulmonary tuberculosis casesTuberculosis control effortsHigh-incidence settingsMycobacterium tuberculosis isolatesCluster investigationsTuberculosis notification ratesPost-implementation dataComplex public health interventionsPopulation-level interventionsPublic health interventionsMIRU-VNTR typingTuberculosis infectionTuberculosis casesPreventive treatmentPublic health outcomesNotification ratesTuberculosis isolatesSenior Research FellowshipDeterministic compartmental modelProportion of individuals
2011
Modelling the performance of isoniazid preventive therapy for reducing tuberculosis in HIV endemic settings: the effects of network structure
Mills HL, Cohen T, Colijn C. Modelling the performance of isoniazid preventive therapy for reducing tuberculosis in HIV endemic settings: the effects of network structure. Journal Of The Royal Society Interface 2011, 8: 1510-1520. PMID: 21508012, PMCID: PMC3163428, DOI: 10.1098/rsif.2011.0160.Peer-Reviewed Original ResearchConceptsTB diseaseLatent M. tuberculosis infectionEffects of IptHIV-endemic settingsActive tuberculosis diseaseIsoniazid preventive therapyIntact immune systemM. tuberculosis infectionWorld Health OrganizationPreventive therapyTB casesTuberculosis infectionTuberculosis diseaseClinical trialsEndemic settingsIPT programHigh riskLatent infectionSingle drugCommunity-wide levelRespiratory contactHIVImmune systemPopulation-level impactUse of IPT
2006
Exogenous re-infection and the dynamics of tuberculosis epidemics: local effects in a network model of transmission
Cohen T, Colijn C, Finklea B, Murray M. Exogenous re-infection and the dynamics of tuberculosis epidemics: local effects in a network model of transmission. Journal Of The Royal Society Interface 2006, 4: 523-531. PMID: 17251134, PMCID: PMC2373405, DOI: 10.1098/rsif.2006.0193.Peer-Reviewed Original ResearchConceptsTB control strategiesPublic health policy makersType of TBMolecular epidemiologic toolsHealth policy makersTB diseasePrimary diseasePrimary progressionTB incidenceRecent infectionTB transmissionTuberculosis diseaseInfectious disease transmissionTuberculosis epidemicRecent transmissionEpidemiological dataForce of infectionInfectious casesLatent infectionEpidemiologic toolInfectionMycobacterium tuberculosisSpecific populationsDiseaseEpidemic trajectories