2023
Prognostic Impact of Repeated NT-proBNP Measurements in Patients With Heart Failure With Reduced Ejection Fraction
Fuery M, Leifer E, Samsky M, Sen S, O'Connor C, Fiuzat M, Ezekowitz J, Piña I, Whellan D, Mark D, Felker G, Desai N, Januzzi J, Ahmad T. Prognostic Impact of Repeated NT-proBNP Measurements in Patients With Heart Failure With Reduced Ejection Fraction. JACC Heart Failure 2023, 12: 479-487. PMID: 38127049, DOI: 10.1016/j.jchf.2023.11.007.Peer-Reviewed Original ResearchNT-proBNP measurementsPrimary trial endpointChronic heart failureNT-proBNP levelsReduced ejection fractionTrial endpointsHeart failureEjection fractionN-terminal pro-B-type natriuretic peptide (NT-proBNP) measurementBaseline NT-proBNP levelsChronic heart failure patientsNT-proBNP monitoringSecondary trial endpointsHeart failure hospitalizationNatriuretic peptide measurementHeart failure patientsCardiovascular deathFailure hospitalizationNT-proBNPFailure patientsPrognostic impactClinical outcomesPrognostic valueOutpatient sitesClinical studies
2019
Chloride Homeostasis in End Stage Heart Failure and LVAD Recipients
Stawiarski K, Agboola O, Jacoby D, Bellumkonda L, Ahmad T, Sugeng L, Chen M, McCloskey G, Geirsson A, Anwar M, Bonde P. Chloride Homeostasis in End Stage Heart Failure and LVAD Recipients. The Journal Of Heart And Lung Transplantation 2019, 38: s382-s383. DOI: 10.1016/j.healun.2019.01.974.Peer-Reviewed Original ResearchSerum chloride levelsChloride homeostasisLVAD patientsHeart failureLVAD therapyEnd-stage heart failureCardio-renal axisChronic heart failureStage heart failureChloride levelsLong-term survivalKaplan-Meir plotsLog-rank statisticsL riseCause mortalityLVAD recipientsWorse survivalSingle centerNeurohormonal responsesPrognostic implicationsPrognostic valueLVAD implantsRetrospective analysisGroup ACox model
2013
Therapeutic Implications of Biomarkers in Chronic Heart Failure
Ahmad T, O'Connor C. Therapeutic Implications of Biomarkers in Chronic Heart Failure. Clinical Pharmacology & Therapeutics 2013, 94: 468-479. PMID: 23856627, DOI: 10.1038/clpt.2013.139.Peer-Reviewed Original ResearchConceptsChronic heart failureHeart failureTherapeutic implicationsBiomarker-guided clinical trialsTreatment of HFPotential therapeutic implicationsClinical trial designImportant therapeutic implicationsUse of biomarkersHemodynamic disordersClinical trialsClinical careTrial designTherapeutic potentialBiomarker studiesMolecular biomarkersBiomarkersMolecular dysfunctionMolecular pathwaysDysfunctionFailurePathophysiologySyndromeTrialsCareRELATIONSHIP BETWEEN EXERCISE TRAINING AND CHANGES IN BIOMARKERS OF MYOCARDIAL STRESS, INJURY AND INFLAMMATION IN PATIENTS WITH CHRONIC HEART FAILURE
Ahmad T, Fiuzat M, Neely B, Neely M, Adams K, Whellan D, Donahue M, Kitzman D, Pina I, Zannad F, Kraus W, O'Connor C, Felker G. RELATIONSHIP BETWEEN EXERCISE TRAINING AND CHANGES IN BIOMARKERS OF MYOCARDIAL STRESS, INJURY AND INFLAMMATION IN PATIENTS WITH CHRONIC HEART FAILURE. Journal Of The American College Of Cardiology 2013, 61: e759. DOI: 10.1016/s0735-1097(13)60759-7.Peer-Reviewed Original Research
2012
INTERACTION BETWEEN ST2 LEVELS AND EXERCISE TRAINING IN PATIENTS WITH CHRONIC HEART FAILURE: ANALYSIS FROM THE HF-ACTION TRIAL
Ahmad T, Felker G, Fiuzat M, Thompson V, Shaw L, Adams K, Whellan D, Donahue M, Kitzman D, Pina I, Zannad F, Kraus W, O'Connor C. INTERACTION BETWEEN ST2 LEVELS AND EXERCISE TRAINING IN PATIENTS WITH CHRONIC HEART FAILURE: ANALYSIS FROM THE HF-ACTION TRIAL. Journal Of The American College Of Cardiology 2012, 59: e940. DOI: 10.1016/s0735-1097(12)60941-3.Peer-Reviewed Original Research