Penta-fluorophenol: a Smiles rearrangement-inspired cysteine-selective fluorescent probe for imaging of human glioblastoma
An J, Kang S, Huh E, Kim Y, Lee D, Jo H, Joung J, Kim V, Lee J, Dho Y, Jung Y, Hur J, Park C, Jung J, Huh Y, Ku J, Kim S, Chowdhury T, Park S, Kang J, Oh M, Park C, Kim D. Penta-fluorophenol: a Smiles rearrangement-inspired cysteine-selective fluorescent probe for imaging of human glioblastoma. Chemical Science 2020, 11: 5658-5668. PMID: 32874505, PMCID: PMC7449700, DOI: 10.1039/d0sc01085e.Peer-Reviewed Original ResearchLong-term toxicitySpecific diagnostic proceduresClinical biopsy samplesHuman-derived cellsImmune responseIndividual patientsMouse modelGlioblastoma patientsBiopsy samplesNew biomarkersClinical sitesDisease sitesHuman tissue samplesDiagnostic proceduresGBM cellsHuman glioblastomaTreatment progressTissue samplesClinical samplesCysteine levelsPatientsPrecision diagnosisPresent findingsGBMImaging