A systematic review on the efficacy of GLP-1 receptor agonists in mitigating psychotropic drug-related weight gain.
Menon T, Lee S, Gong X, Wong S, Le G, Kwan A, Teopiz K, Ho R, Cao B, Rhee T, Jing Zheng Y, Valentino K, Lin K, Vinberg M, Lo H, McIntyre R. A systematic review on the efficacy of GLP-1 receptor agonists in mitigating psychotropic drug-related weight gain. CNS Spectrums 2024, 1-7. PMID: 39582175, DOI: 10.1017/s1092852924000531.Peer-Reviewed Original ResearchPsychiatric medicationsEffects of GLP-1RAsReceptor agonistsEfficacy of GLP-1 receptor agonistsRandomized controlled trialsGLP-1RAsModerate weight changeMitigate weight gainPsychiatric populationsPsychotropic drugsCognitive processesWeight gainClinically meaningful effectGlucagon-like peptide-1 receptor agonistsPeptide-1 receptor agonistsGLP-1 receptor agonistsSystematic reviewPreliminary evidenceGlucose-lowering agentsLong-term safetyWeight changeMeaningful effectEfficacy profilePersonsAbnormal weightEfficacy of esketamine for perinatal depression: a systematic review and meta-analysis.
Wong S, Le G, Kwan A, Teopiz K, Rhee T, Ho R, Rosenblat J, Mansur R, McIntyre R. Efficacy of esketamine for perinatal depression: a systematic review and meta-analysis. CNS Spectrums 2024, 1-9. PMID: 39479775, DOI: 10.1017/s1092852924000452.Peer-Reviewed Original ResearchPostpartum depressionPerinatal depressionPrevention of postpartum depressionIncidence of postpartum depressionReduced health-related quality of lifeHealth-related quality of lifeSystematic reviewTreatment of postpartum depressionWeeks of childbirthMeta-analysisWeeks post-deliveryClinically meaningful implicationsQuality of lifeRandomized controlled trialsRandom-effects modelDecreased incidencePain managementPostpartum periodChildbirth laborIncidence ratePost-deliveryPsychosocial functioningEligibility criteriaControlled trialsPrimary outcomeCorrection: Subjective and objective measures of cognitive function are correlated in persons with Post-COVID-19 Condition: a secondary analysis of a Randomized Controlled Trial
Kwan A, Lakhani M, Le G, Singh G, Teopiz K, Ceban F, Nijjar C, Meshkat S, Badulescu S, Ho R, Rhee T, Di Vincenzo J, Gill H, McIntyre R. Correction: Subjective and objective measures of cognitive function are correlated in persons with Post-COVID-19 Condition: a secondary analysis of a Randomized Controlled Trial. European Archives Of Psychiatry And Clinical Neuroscience 2024, 274: 1967-1968. PMID: 39307886, DOI: 10.1007/s00406-024-01910-z.Peer-Reviewed Original ResearchMeasures of cognitive functionPost-COVID-19 conditionRandomized controlled trialsSecondary analysisControlled trialsCognitive functionSubjective and objective measures of cognitive function are correlated in persons with Post-COVID-19 Condition: a secondary analysis of a Randomized Controlled Trial
Kwan A, Lakhani M, Le G, Singh G, Teopiz K, Ceban F, Nijjar C, Meshkat S, Badulescu S, Ho R, Rhee T, Di Vincenzo J, Gill H, McIntyre R. Subjective and objective measures of cognitive function are correlated in persons with Post-COVID-19 Condition: a secondary analysis of a Randomized Controlled Trial. European Archives Of Psychiatry And Clinical Neuroscience 2024, 274: 1959-1966. PMID: 39190040, DOI: 10.1007/s00406-024-01877-x.Peer-Reviewed Original ResearchDigit Symbol Substitution TestMeasures of cognitive functionPDQ-20Cognitive functionPerceived Deficits QuestionnairePost-COVID-19 conditionObjective cognitive functioningMeasures of cognitionTMT-A scoresPlacebo-controlled clinical trialMethodsThis post hoc analysisSubstitution TestTMT-BTMT-APost hoc analysisRandomized controlled trialsDouble-blindClinical implicationsStatistically significant correlationCharacterized cohortClinical trialsCognitionPatient-reported measuresControlled trialsFunctional complaints