2020
Transient receptor potential channels in pulmonary chemical injuries and as countermeasure targets
Achanta S, Jordt S. Transient receptor potential channels in pulmonary chemical injuries and as countermeasure targets. Annals Of The New York Academy Of Sciences 2020, 1480: 73-103. PMID: 32892378, PMCID: PMC7933981, DOI: 10.1111/nyas.14472.Peer-Reviewed Original ResearchConceptsChemical injuryTRP channelsNeurogenic inflammatory pathwaysChemical threat agentsMediator of injuryTransient receptor potential channelsTransient receptor potential (TRP) ion channelsIntracellular calcium levelsToxic inhalation hazardPotential ion channelsCough reflexPulmonary injuryPulmonary edemaProinflammatory cellsInflammatory pathwaysPathophysiologic eventsOccupational exposureMucus clearanceCalcium levelsInjuryNonneuronal pathwaysRespiratory systemBroader indicationsPotential channelsInhalation hazard
2007
Trp Channels In Disease
JORDT SE, EHRLICH BE. Trp Channels In Disease. Subcellular Biochemistry 2007, 45: 253-271. PMID: 18193640, DOI: 10.1007/978-1-4020-6191-2_9.Peer-Reviewed Original ResearchConceptsTRP channelsTransient receptor potential channelsPainful stimuliTRPA (ankyrin) groupsRole of TrpIntracellular Ca2Intracellular storesTRP channel physiologyDiseaseNormal physiologyChannel physiologySpecific diseasesPathophysiologyPotential channelsDifferent TRPsExtracellular stimuliMain subfamiliesDistinct functionsChemical signalsStimuliPhysiologyLarge familyMutationsProgression