2017
Lack of Effect of Murine Astrovirus Infection on Dextran Sulfate-induced Colitis in NLRP3-deficient Mice.
Compton SR, Booth CJ, Macy JD. Lack of Effect of Murine Astrovirus Infection on Dextran Sulfate-induced Colitis in NLRP3-deficient Mice. Comparative Medicine 2017, 67: 400-406. PMID: 28935001, PMCID: PMC5621567.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAstroviridaeAstroviridae InfectionsColitisColonDextran SulfateDisease Models, AnimalFemaleGastrointestinal MicrobiomeInflammasomesMaleMiceMice, Inbred C57BLNLR Family, Pyrin Domain-Containing 3 ProteinRandom AllocationReal-Time Polymerase Chain ReactionReproducibility of ResultsRodent DiseasesRodentiaConceptsColitis modelInflammatory bowel disease researchNOD-like receptor 3Induced colitis modelSeverity of colitisDextran sodium sulfateDSS colitis modelNLRP3-deficient miceDefective inflammasome activationLack of effectMucosal ulcerationIntestinal inflammationHistopathologic changesIntestinal permeabilityAstrovirus infectionFemale miceClinical signsDeficient miceNLRP3 mutationsClinical diseaseInflammasome activationGastrointestinal tractMurine astrovirusIntestinal bacteriaIntestinal epitheliumMurine Astrovirus Infection and Transmission in Neonatal CD1 Mice.
Compton SR, Booth CJ, Macy JD. Murine Astrovirus Infection and Transmission in Neonatal CD1 Mice. Journal Of The American Association For Laboratory Animal Science 2017, 56: 402-411. PMID: 28724490, PMCID: PMC5517330.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornAstroviridae InfectionsAvastrovirusFecesFemaleHousing, AnimalMaleMiceRodent Diseases
2015
Effect of Cage-Wash Temperature on the Removal of Infectious Agents from Caging and the Detection of Infectious Agents on the Filters of Animal Bedding-Disposal Cabinets by PCR Analysis.
Compton SR, Macy JD. Effect of Cage-Wash Temperature on the Removal of Infectious Agents from Caging and the Detection of Infectious Agents on the Filters of Animal Bedding-Disposal Cabinets by PCR Analysis. Journal Of The American Association For Laboratory Animal Science 2015, 54: 745-55. PMID: 26632784, PMCID: PMC4671790.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDisinfectionFemaleHousing, AnimalMicePolymerase Chain ReactionRodent DiseasesTemperatureVirus DiseasesConceptsMouse hepatitis virusMouse parvovirusMyocoptes musculinusInfectious agentsS. obvelataDetection of infectionHepatitis virusPCR analysisHousing micePathogen transmissionFacility levelMiceCages housing miceHelicobacter sppM. pulmonisSyphacia obvelataMycoplasma pulmonisCage washingParvovirusAnimal facilitiesSentinelsVirusAgentsPulmonisPathogen screening
2013
Effect of immunodeficiency on MPV shedding and transmission.
Macy JD, Paturzo FX, Compton SR. Effect of immunodeficiency on MPV shedding and transmission. Journal Of The American Association For Laboratory Animal Science 2013, 52: 467-74. PMID: 23849445, PMCID: PMC3725932.Peer-Reviewed Original Research
2012
Transmission of mouse parvovirus to neonatal mice.
Compton SR, Paturzo FX, Macy JD. Transmission of mouse parvovirus to neonatal mice. Journal Of The American Association For Laboratory Animal Science 2012, 51: 797-802. PMID: 23294886, PMCID: PMC3508184.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornFecesFemaleHousing, AnimalMaleMiceParvoviridae InfectionsParvovirusRodent DiseasesAge-associated variability in susceptibility of Swiss Webster mice to MPV and other excluded murine pathogens.
Grove KA, Smith PC, Booth CJ, Compton SR. Age-associated variability in susceptibility of Swiss Webster mice to MPV and other excluded murine pathogens. Journal Of The American Association For Laboratory Animal Science 2012, 51: 789-96. PMID: 23294885, PMCID: PMC3508183.Peer-Reviewed Original ResearchConceptsSwiss Webster miceSoiled-bedding sentinelsInfectious agentsMouse parvovirusWebster miceMurine pathogenHealth surveillance protocolsAge-associated variabilityMode of transmissionContact sentinelsIndex miceSentinel miceMice ageHealth surveillanceMiceLocal pet storesMurine coloniesHost susceptibilityResearch colonyAgeSentinelsAgentsSusceptibilityPet storesPathogensTransmission of mouse parvovirus by fomites.
Compton SR, Paturzo FX, Smith PC, Macy JD. Transmission of mouse parvovirus by fomites. Journal Of The American Association For Laboratory Animal Science 2012, 51: 775-80. PMID: 23294883, PMCID: PMC3508181.Peer-Reviewed Original Research