2024
Exploring fidelity of enactment in a cluster randomised controlled trial testing the effectiveness of ‘gatekeeper’ training for pesticide vendors in reducing self-poisoning in rural Sri Lanka: protocol for a multimethod qualitative study
Kanapathy R, Agampodi T, Eddleston M, Konradsen F, Pearson M, Sanjula B, Malalasekara C, Naseer N, Agampodi S, Weerasinghe M. Exploring fidelity of enactment in a cluster randomised controlled trial testing the effectiveness of ‘gatekeeper’ training for pesticide vendors in reducing self-poisoning in rural Sri Lanka: protocol for a multimethod qualitative study. BMJ Open 2024, 14: e082688. PMID: 38977371, PMCID: PMC11256041, DOI: 10.1136/bmjopen-2023-082688.Peer-Reviewed Original ResearchConceptsCluster randomised controlled trialRandomised controlled trialsRural Sri LankaPesticide self-poisoningControlled trialsStepped-wedge cluster randomised controlled trialPesticide vendorsScientific peer-reviewed journalsMiddle-income countriesEthics and Research CommitteeSelf-poisoningMultimethod qualitative studyPeer-reviewed journalsFocus group discussionsIntervention fidelityIntervention districtsStratified purposive sampling methodReplicate interventionsQualitative research designSocioeconomic hardshipQualitative studyConference presentationsGroup discussionsRajarata UniversityParticipant diariesGlobal burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Collaborators G, Brauer M, Roth G, Aravkin A, Zheng P, Abate K, Abate Y, Abbafati C, Abbasgholizadeh R, Abbasi M, Abbasian M, Abbasifard M, Abbasi-Kangevari M, ElHafeez S, Abd-Elsalam S, Abdi P, Abdollahi M, Abdoun M, Abdulah D, Abdullahi A, Abebe M, Abedi A, Abedi A, Abegaz T, Zuñiga R, Abiodun O, Abiso T, Aboagye R, Abolhassani H, Abouzid M, Aboye G, Abreu L, Abualruz H, Abubakar B, Abu-Gharbieh E, Abukhadijah H, Aburuz S, Abu-Zaid A, Adane M, Addo I, Addolorato G, Adedoyin R, Adekanmbi V, Aden B, Adetunji J, Adeyeoluwa T, Adha R, Adibi A, Adnani Q, Adzigbli L, Afolabi A, Afolabi R, Afshin A, Afyouni S, Afzal M, Afzal S, Agampodi S, Agbozo F, Aghamiri S, Agodi A, Agrawal A, Agyemang-Duah W, Ahinkorah B, Ahmad A, Ahmad D, Ahmad F, Ahmad N, Ahmad S, Ahmad T, Ahmed A, Ahmed A, Ahmed A, Ahmed L, Ahmed M, Ahmed S, Ahmed S, Ajami M, Akalu G, Akara E, Akbarialiabad H, Akhlaghi S, Akinosoglou K, Akinyemiju T, Akkaif M, Akkala S, Akombi-Inyang B, Al Awaidy S, Al Hasan S, Alahdab F, AL-Ahdal 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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet 2024, 403: 2162-2203. PMID: 38762324, PMCID: PMC11120204, DOI: 10.1016/s0140-6736(24)00933-4.Peer-Reviewed Original ResearchConceptsDisability-adjusted life yearsHigh body-mass indexTheoretical minimum risk exposure levelSocio-demographic indexBody-mass indexRisk-outcome pairsParticulate matter air pollutionChild growth failureBurden of diseaseGlobal disease burdenGlobal burdenHealth outcomesRisk factorsDisease burdenMetabolic riskAmbient particulate matter air pollutionSocio-demographic Index locationsGlobal Burden of Disease StudyBurden of Disease StudyGlobal Burden of DiseaseComparative risk assessment frameworkAge-standardised ratesExposure to risk factorsPopulation attributable fractionSpecific health outcomesGlobal burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
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Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet 2024, 403: 2100-2132. PMID: 38582094, PMCID: PMC11126520, DOI: 10.1016/s0140-6736(24)00367-2.Peer-Reviewed Original ResearchConceptsAge-standardised death ratesChronic obstructive pulmonary diseaseGlobal burdenLife expectancyObstructive pulmonary diseaseGlobal life expectancyHighest age-standardised death ratesLower respiratory infectionsDeath rateCause-specific death ratesGlobal Burden of Disease StudyCause-of-death dataDecompose life expectancyLatin AmericaBurden of Disease StudyGlobal Burden of DiseaseHigh-income super-regionAge-standardised deathAge-standardised ratesSubnational locationsStudy periodOut-of-sample predictive validityCause-of-death estimatesCause-specific estimatesGBD super-regionsStigma associated with cutaneous leishmaniasis in rural Sri Lanka: development of a conceptual framework
Nuwangi H, Dikomitis L, Weerakoon K, Liyanage C, Agampodi T, Agampodi S. Stigma associated with cutaneous leishmaniasis in rural Sri Lanka: development of a conceptual framework. International Health 2024, ihae021. PMID: 38487983, DOI: 10.1093/inthealth/ihae021.Peer-Reviewed Original ResearchDisease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2024, 10: 1028. PMID: 38504849, PMCID: PMC10948970, DOI: 10.12688/f1000research.52539.4.Peer-Reviewed Original ResearchCardiovascular diseasePeriod of amenorrhoeaBurden of CVDAdverse pregnancy outcomesEffects of CVDProspective cohort studyCardiovascular disease morbidityEvidence-based guidelinesRoutine clinical assessmentRisk prediction modelPostpartum morbidityPregnancy clinicWard admissionAntenatal careCohort studyPregnancy outcomesMaternal deathsMiddle-income countriesCVD burdenDisease morbidityEarly pregnancyFirst trimesterPregnant womenMaternal mortalityAppropriate referralDisease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2024, 10: 1028. DOI: 10.12688/f1000research.52539.4.Peer-Reviewed Original ResearchCardiovascular diseaseBurden of cardiovascular diseasePeriod of amenorrhoeaMedical Officer of Health (MOHCardiovascular disease morbidityCardiovascular disease burdenMiddle-income countriesEvidence-based guidelinesProspective cohort studyEffects of cardiovascular diseaseRisk prediction modelDisease complicating pregnancyAntenatal careMaternal mortalityPostpartum morbidityMaternal deathsPostpartum hemorrhageWard admissionTelephone interviewsConsultant cardiologistCohort studyDisease morbidityPregnancy clinicEligibility criteriaDisease burdenLevels of Cytokines in Leptospirosis Patients with Different Serovars and rfb Locus
Senavirathna I, Jayasundara D, Warnasekara J, Kappagoda C, Agampodi S. Levels of Cytokines in Leptospirosis Patients with Different Serovars and rfb Locus. Journal Of Interferon & Cytokine Research 2024, 44: 80-93. PMID: 38377491, PMCID: PMC10880283, DOI: 10.1089/jir.2023.0091.Peer-Reviewed Original ResearchConceptsRfb locusGenome sequencePacBio RS II systemBacterial cell wallCulture-positive samplesLipopolysaccharide synthesisRapid AnnotationLeptospira borgpetersenii</i>,Genomic dataMicroscopic agglutination testSubsystem TechnologyLociCell wallSerovarsIsolated culturesSevere clinical manifestationsCytokine responsesLeptospira interrogans serovar autumnalisClinical manifestationsGenomeSamples of cultureSequenceRFBLevels of cytokinesSerum cytokine concentrationsThe psychosocial burden of cutaneous leishmaniasis in rural Sri Lanka: A multi-method qualitative study.
Nuwangi H, Dikomitis L, Weerakoon K, Agampodi S, Agampodi T. The psychosocial burden of cutaneous leishmaniasis in rural Sri Lanka: A multi-method qualitative study. PLOS Neglected Tropical Diseases 2024, 18: e0011909. PMID: 38236911, PMCID: PMC10826957, DOI: 10.1371/journal.pntd.0011909.Peer-Reviewed Original ResearchConceptsPsychosocial burdenRural Sri LankaPeople-centred careMulti-method qualitative studyPerceived disease severityHigh psychosocial burdenTreatment-related burdenImprove patient outcomesHealthcare seekingStigmatised diseaseIllness experienceIllness-experienceHealthcare modelRelated burdenBody image concernsBurden of CLThematic analysisQualitative studyHospital clinicMultimethod qualitative approachResource-poor regionsDisease burdenNegative societal reactionsPatient outcomesCommunity engagementGetting leptospirosis onto the lists of neglected tropical diseases
Vinetz J, Chetrick A, Steimel K, Devillers C, Excler J, Kim J, Agampodi S. Getting leptospirosis onto the lists of neglected tropical diseases. Open Access Government 2024, 43: 52-54. DOI: 10.56367/oag-043-11310.Peer-Reviewed Original Research
2023
Stigma associated with cutaneous and mucocutaneous leishmaniasis: A systematic review
Nuwangi H, Agampodi T, Price H, Shepherd T, Weerakoon K, Agampodi S. Stigma associated with cutaneous and mucocutaneous leishmaniasis: A systematic review. PLOS Neglected Tropical Diseases 2023, 17: e0011818. PMID: 38153950, PMCID: PMC10781107, DOI: 10.1371/journal.pntd.0011818.Peer-Reviewed Original ResearchWhole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka
Senavirathna I, Jayasundara D, Warnasekara J, Matthias M, Vinetz J, Agampodi S. Whole genome sequencing data of Leptospira weilii and Leptospira kirschneri isolated from human subjects of Sri Lanka. Data In Brief 2023, 52: 109840. PMID: 38059003, PMCID: PMC10696454, DOI: 10.1016/j.dib.2023.109840.Peer-Reviewed Original ResearchGenome sequenceSingle-molecule real-time platformsNCBI Prokaryotic Genome Annotation PipelineLeptospira weiliiHigh-quality genomic DNAProkaryotic Genome Annotation PipelineComparative genomic analysisWhole-genome sequencing dataComplete genome sequenceGenome Annotation PipelineGenome sequencing dataLeptospira kirschneriMid-log phase culturesWhole-genome sequencingGenome featuresGenomic analysisAnnotation pipelineGenomic DNASequencing dataGenome sequencingNovel strainMolecular diagnostic toolsPhase culturesSpeciesGenus LeptospiraOut-of-Pocket Expenditure for Antenatal Care Amid Free Health Care Provision: Evidence From a Large Pregnancy Cohort in Rural Sri Lanka
Gunarathna S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Out-of-Pocket Expenditure for Antenatal Care Amid Free Health Care Provision: Evidence From a Large Pregnancy Cohort in Rural Sri Lanka. Global Health Science And Practice 2023, 11: e2200410. PMID: 37903576, PMCID: PMC10615247, DOI: 10.9745/ghsp-d-22-00410.Peer-Reviewed Original ResearchConceptsMean OOP expenditureAntenatal careLarge pregnancy cohortPrivate health facilitiesPregnant womenHealth facilitiesOOP expenditureMaternal morbidityIndependent predictorsPrevious pregnancyPregnancy cohortHealth service utilizationInterviewer-administered questionnaireSignificant independent predictorsGovernment health facilitiesGovernment health servicesCare modeLaboratory investigationsHealth care usersSelf-administered questionnaireSri Lankan settingMonthly household incomeHealth care provisionANC visitsThird trimesterDifferences in the characteristics of people who purchase pesticides from shops for self‐harm versus those who use pesticides available in the domestic environment in Sri Lanka
Weerasinghe M, Jobe L, Konradsen F, Eddleston M, Pearson M, Jayamanne S, Hawton K, Gunnell D, Agampodi S. Differences in the characteristics of people who purchase pesticides from shops for self‐harm versus those who use pesticides available in the domestic environment in Sri Lanka. Tropical Medicine And International Health 2023, 28: 901-911. PMID: 37871998, DOI: 10.1111/tmi.13941.Peer-Reviewed Original ResearchConceptsHigh suicide intentSuicide attemptsSuicide intentSuicide deathsConfidence interval -3.2Pesticide poisoning casesLogistic regression analysisCI 1.5Fatal casesCharacteristics of peopleRural Sri LankaPoisoning casesDomestic casesRegression analysisPrevention implicationsSurvivorsHigher proportionDeathMitigating the effects of climate change on human health with vaccines and vaccinations
Kim C, Agampodi S, Marks F, Kim J, Excler J. Mitigating the effects of climate change on human health with vaccines and vaccinations. Frontiers In Public Health 2023, 11: 1252910. PMID: 37900033, PMCID: PMC10602790, DOI: 10.3389/fpubh.2023.1252910.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virus infectionCost-effective public health interventionsSyncytial virus infectionVaccine-preventable diseasesPublic health interventionsUse of vaccinesResource-poor countriesTransmissible infectious diseasesPublic health consequencesWorld Health OrganizationBody of evidenceHelminthic infectionsVirus infectionVaccine researchGlobal vaccine developmentVaccine developmentHealth interventionsNarrative reviewInfectious diseasesHealth consequencesVaccinationDiseaseAvailable evidenceHealth OrganizationVaccineIncorporating early pregnancy mental health screening and management into routine maternal care: experience from the Rajarata Pregnancy Cohort (RaPCo), Sri Lanka
Agampodi T, Amarasinghe G, Wickramasinghe A, Wickramasinghe N, Warnasekara J, Jayasinghe I, Hettiarachchi A, Nimesha D, Dilshani T, Senadheera S, Agampodi S. Incorporating early pregnancy mental health screening and management into routine maternal care: experience from the Rajarata Pregnancy Cohort (RaPCo), Sri Lanka. BMJ Global Health 2023, 8: e012852. PMID: 37748792, PMCID: PMC10533714, DOI: 10.1136/bmjgh-2023-012852.Peer-Reviewed Original ResearchConceptsEdinburgh Postnatal Depression ScaleMental health screeningMental health problemsPregnancy cohortSecond trimesterEarly pregnancyHealth screeningClinical InterviewHealth problemsPregnancy care programsRoutine maternal careTertiary care hospitalMental health service provisionPrimary healthcare levelHigher EPDS scoresPostnatal Depression ScaleWeeks of periodPregnancy-associated conditionsMental health gapPatient-centered careHealth service provisionHealth surveillance systemsCare hospitalMiddle-income countriesPregnant womenThe Effect of Salacia Reticulata Extract Biscuits on Blood Sugar Control of Type 2 Diabetes Mellitus Patients: A Two-Period, Two-Sequence, Crossover, Randomized, Triple-Blind, Placebo-Controlled, Clinical Trial
Siribaddana S, Medagama A, Wickramasinghe N, Siribaddana N, Agampodi S, Fernando D. The Effect of Salacia Reticulata Extract Biscuits on Blood Sugar Control of Type 2 Diabetes Mellitus Patients: A Two-Period, Two-Sequence, Crossover, Randomized, Triple-Blind, Placebo-Controlled, Clinical Trial. Cureus 2023, 15: e45921. PMID: 37885536, PMCID: PMC10599346, DOI: 10.7759/cureus.45921.Peer-Reviewed Original ResearchType 2 diabetesKothala-himbutuPlacebo biscuitsBiscuit groupTwo-sequenceComputer-generated random numbersTeaching Hospital AnuradhapuraMean HbA1c levelBlood sugar controlPrimary outcome measureTwo-periodHbA1c levelsMean HbA1cGlycemic stabilityGlycemic controlMellitus patientsCrossover studyWashout periodSugar controlHeart diseaseTreatment allocationClinical trialsOutcome measuresPlaceboPatientsPerinatal mental health in Sri Lanka, current status, programmes, gaps, and recommendations.
Agampodi T, Agampodi S. Perinatal mental health in Sri Lanka, current status, programmes, gaps, and recommendations. Ceylon Medical Journal 2023, 68: 53-57. PMID: 37610969, DOI: 10.4038/cmj.v68isi 1.9792.Peer-Reviewed Original ResearchGlobal, regional, and country-level cost of leptospirosis due to loss of productivity in humans
Agampodi S, Gunarathna S, Lee J, Excler J. Global, regional, and country-level cost of leptospirosis due to loss of productivity in humans. PLOS Neglected Tropical Diseases 2023, 17: e0011291. PMID: 37616329, PMCID: PMC10482283, DOI: 10.1371/journal.pntd.0011291.Peer-Reviewed Original ResearchConceptsGross domestic productDisability-adjusted life yearsProductivity costsWorld Bank data repositoryLoss of productivityHealth expenditure dataEconomic burden estimatesHigher productivity costsDomestic productExpenditure dataInternational dollarsOverall economic burdenMonetary valueEconomic burdenAsia-Pacific regionIntangible costsLife yearsEconomic costsCost estimatesIncome countriesDiseases of povertyPartial estimatesCostProductivityCountriesPerinatal mental health in Sri Lanka, current status, programmes, gaps, and recommendations
Agampodi T, Agampodi S. Perinatal mental health in Sri Lanka, current status, programmes, gaps, and recommendations. Ceylon Medical Journal 2023, 68: 53-57. DOI: 10.4038/cmj.v68isi1.9792.Peer-Reviewed Original ResearchSafeguarding community-centred global health research during crises
Agampodi T, Nuwangi H, Gunasekara S, Mallawaarachchi A, Price H, Dikomitis L, Agampodi S. Safeguarding community-centred global health research during crises. BMJ Global Health 2023, 8: e013304. PMID: 37532463, PMCID: PMC10401201, DOI: 10.1136/bmjgh-2023-013304.Peer-Reviewed Original Research