Utility and Limitations of Direct Multi-Locus Sequence Typing on qPCR-Positive Blood to Determine Infecting Leptospira Strain
Agampodi SB, Moreno AC, Vinetz JM, Matthias MA. Utility and Limitations of Direct Multi-Locus Sequence Typing on qPCR-Positive Blood to Determine Infecting Leptospira Strain. American Journal Of Tropical Medicine And Hygiene 2012, 88: 184-185. PMID: 23208890, PMCID: PMC3541733, DOI: 10.4269/ajtmh.2012.12-0526.Peer-Reviewed Original ResearchConceptsPolymerase chain reaction-positive samplesBacterial loadLeptospira strainsMLST profilesAcute illnessBlood samplesHuman leptospirosisComplete MLST profilesCulture isolationMulti-locus sequenceHuman bloodSequence typesBloodCentral Sri LankaInterpretable dataMolecular characterizationIllnessLeptospirosisST44