Chronic Lung Allograft Dysfunction: Role for Tumor Suppressor Gene Liver Kinase B1
Rahman M, Ravichandran R, Bansal S, Liu W, Perincheri S, Angara S, Fleming T, Bharat A, Hachem R, Smith M, Bremner R, Mohanakumar T. Chronic Lung Allograft Dysfunction: Role for Tumor Suppressor Gene Liver Kinase B1. The Journal Of Heart And Lung Transplantation 2021, 40: s60. DOI: 10.1016/j.healun.2021.01.1886.Peer-Reviewed Original ResearchChronic lung allograft dysfunctionBronchiolitis obliterans syndromeLung transplant modelLung transplant recipientsLiver kinase B1Epithelial-mesenchymal transformationΑ-SMAChronic rejectionTransplant recipientsBEAS-2BTransplant modelHypoxia/reperfusion (H/R) modelKnockdown of LKB1Lung allograft dysfunctionQRT-PCRAirway epithelial cell lineMiR-155 levelsExosome releaseHypoxia/reperfusionRole of LKB1Upregulation of vimentinAllograft dysfunctionLung transplantationObliterans syndromeCLAD development