2023
Bone marrow sinusoidal endothelial cells are a site of Fgf23 upregulation in a mouse model of iron deficiency anemia
Li X, Lozovatsky L, Tommasini S, Fretz J, Finberg K. Bone marrow sinusoidal endothelial cells are a site of Fgf23 upregulation in a mouse model of iron deficiency anemia. Blood Advances 2023, 7: 5156-5171. PMID: 37417950, PMCID: PMC10480544, DOI: 10.1182/bloodadvances.2022009524.Peer-Reviewed Original ResearchMeSH KeywordsAnemia, Iron-DeficiencyAnimalsBone MarrowDisease Models, AnimalEndothelial CellsErythropoietinIronMiceRNA, MessengerUp-RegulationConceptsSinusoidal endothelial cellsEndothelial cellsBone marrowBM sectionsFGF23 upregulationFibroblast growth factor 23Iron deficiencyElevated serum erythropoietinFGF23 promoter activityBM endothelial cellsGrowth factor 23Vitamin D metabolismIron deficiency anemiaSystemic iron deficiencyKnockout mice exhibitBone marrow sinusoidal endothelial cellsNormal iron balanceNonanemic controlsChronic anemiaFactor 23D metabolismEndothelial cell populationErythropoietin treatmentDeficiency anemiaMouse model
2017
Ibuprofen impairs capsulolabral healing in a rat model of anterior glenohumeral instability
Packer JD, Varthi AG, Zhu DS, Javier FG, Young JD, Garver JV, Henry H, Tommasini SM, Blaine TA. Ibuprofen impairs capsulolabral healing in a rat model of anterior glenohumeral instability. Journal Of Shoulder And Elbow Surgery 2017, 27: 315-324. PMID: 29195899, DOI: 10.1016/j.jse.2017.09.027.Peer-Reviewed Original ResearchConceptsNonsteroidal anti-inflammatory drugsNSAID groupGlenohumeral dislocationRat modelControl groupUninjured limbUse of NSAIDsGlenohumeral instabilityGlenoid labrumAnterior glenohumeral dislocationAnterior-inferior labral tearsAnterior glenohumeral instabilityAnti-inflammatory drugsMatched pair analysisNew rat modelPersistent shoulder instabilityCapsular healingPostinjury administrationInjured limbImpaired healingLabral tearsHistologic analysisShoulder instabilityGlenohumeral stabilityBiomechanical testing