2021
Preoperative risk and postoperative outcome from subdural fluid collections in African infants with postinfectious hydrocephalus.
Lane J, Ssentongo P, Peterson M, Harper J, Mbabazi-Kabachelor E, Mugamba J, Ssenyonga P, Onen J, Donnelly R, Levenbach J, Cherukuri V, Monga V, Kulkarni A, Warf B, Schiff S. Preoperative risk and postoperative outcome from subdural fluid collections in African infants with postinfectious hydrocephalus. Journal Of Neurosurgery Pediatrics 2021, 29: 31-39. PMID: 34598146, PMCID: PMC9078082, DOI: 10.3171/2021.7.peds21209.Peer-Reviewed Original Research
2019
The Incidence of Postoperative Seizures Following Treatment of Postinfectious Hydrocephalus in Ugandan Infants: A Post Hoc Comparison of Endoscopic Treatment vs Shunt Placement in a Randomized Controlled Trial.
Punchak M, Mbabazi Kabachelor E, Ogwal M, Nalule E, Nalwoga J, Ssenyonga P, Mugamba J, Rattani A, Dewan M, Kulkarni A, Schiff S, Warf B. The Incidence of Postoperative Seizures Following Treatment of Postinfectious Hydrocephalus in Ugandan Infants: A Post Hoc Comparison of Endoscopic Treatment vs Shunt Placement in a Randomized Controlled Trial. Neurosurgery 2019, 85: e714-e721. PMID: 31086941, PMCID: PMC7534394, DOI: 10.1093/neuros/nyz122.Peer-Reviewed Original ResearchMeSH KeywordsFemaleFollow-Up StudiesHumansHydrocephalusIncidenceInfantMaleNeuroendoscopyPostoperative ComplicationsSeizuresTreatment OutcomeUgandaVentriculoperitoneal ShuntVentriculostomyConceptsChoroid plexus cauterizationETV/CPCPostoperative seizure incidencePostinfectious hydrocephalusSeizure incidenceEndoscopic third ventriculostomyUgandan infantsShunt placementMantel-Haenszel hazard ratiosKaplan-Meier methodVentriculoperitoneal shunt placementPostoperative epilepsyPostoperative seizuresPreoperative symptomsEpilepsy incidenceFirst seizureHazard ratioControlled TrialsEndoscopic treatmentThird ventriculostomyTreatment modalitiesSeizure riskHead circumferenceRelative riskSeizure onset
2017
Endoscopic Treatment versus Shunting for Infant Hydrocephalus in Uganda
Kulkarni A, Schiff S, Mbabazi-Kabachelor E, Mugamba J, Ssenyonga P, Donnelly R, Levenbach J, Monga V, Peterson M, MacDonald M, Cherukuri V, Warf B. Endoscopic Treatment versus Shunting for Infant Hydrocephalus in Uganda. New England Journal Of Medicine 2017, 377: 2456-2464. PMID: 29262276, PMCID: PMC5784827, DOI: 10.1056/nejmoa1707568.Peer-Reviewed Original ResearchMeSH KeywordsCauteryChild DevelopmentChild LanguageChoroid PlexusCognitionFemaleHumansHydrocephalusInfantMaleMotor SkillsNeuropsychological TestsUgandaVentriculoperitoneal ShuntVentriculostomyConceptsETV-CPCPostinfectious hydrocephalusUgandan infantsTreatment failureCognitive outcomesBrain volumeSingle-center studyEndoscopic third ventriculostomyChoroid plexus cauterizationMajor health problemSignificant differencesLanguage scoresSecondary outcomesEndoscopic treatmentPrimary outcomeVentricular sizeThird ventriculostomyInfant hydrocephalusComputed tomographyTreatment groupsAlternative treatmentLate failureBayley ScalesBrain growthConventional treatment
2011
Costs and benefits of neurosurgical intervention for infant hydrocephalus in sub-Saharan Africa.
Warf B, Alkire B, Bhai S, Hughes C, Schiff S, Vincent J, Meara J. Costs and benefits of neurosurgical intervention for infant hydrocephalus in sub-Saharan Africa. Journal Of Neurosurgery Pediatrics 2011, 8: 509-21. PMID: 22044378, DOI: 10.3171/2011.8.peds11163.Peer-Reviewed Original ResearchConceptsBenefit-cost ratioDisability-adjusted life yearsHuman capital approachEconomic benefitsNeurosurgical interventionCapital approachCost/disability-adjusted life yearStatistical life approachFavorable benefit-cost ratioTotal economic benefitPotential economic impactMajor public health priorityEndoscopic third ventriculostomyBenefits of treatmentCases of hydrocephalusVSL approachPublic health priorityEconomic modelingCURE Children's HospitalTreatment of hydrocephalusEconomic impactLife yearsUntreated hydrocephalusRetrospective reviewShunt placementFive-year survival and outcome of treatment for postinfectious hydrocephalus in Ugandan infants.
Warf B, Dagi A, Kaaya B, Schiff S. Five-year survival and outcome of treatment for postinfectious hydrocephalus in Ugandan infants. Journal Of Neurosurgery Pediatrics 2011, 8: 502-8. PMID: 22044377, DOI: 10.3171/2011.8.peds11221.Peer-Reviewed Original ResearchConceptsPostinfectious hydrocephalusFive-year survivalShunt placementPrimary brain injuryWorse functional outcomeKaplan-Meier methodLong-term outcomesLog-rank testOutcome of treatmentEndoscopic third ventriculostomyTreatment selection biasPublic health measuresOne-thirdUgandan infantsWorst sequelaeOperative mortalityNeonatal infectionFunctional outcomeThird ventriculostomyBrain injuryPrimary treatmentCommon causeInfant hydrocephalusSurvival advantageOriginal infection
2000
Long-Term Follow-Up Data from the Shunt Design Trial
Kestle J, Drake J, Milner R, Sainte-Rose C, Cinalli G, Boop F, Piatt J, Haines S, Schiff S, Cochrane D, Steinbok P, MacNeil N. Long-Term Follow-Up Data from the Shunt Design Trial. Pediatric Neurosurgery 2000, 33: 230-236. PMID: 11155058, DOI: 10.1159/000055960.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolEquipment DesignEquipment FailureFollow-Up StudiesHumansHydrocephalusInfantInfant, NewbornSurvival RateTime FactorsVentriculoperitoneal ShuntConceptsFirst shunt failureShunt failureDifferential pressure valvesOverall shunt survivalShunt Design TrialShunt failure ratesLate complicationsShunt surgeryShunt survivalInitial treatmentTerm followShunt obstructionDelta valvesHydrocephalic childrenOriginal trialPediatric hydrocephalusSurvival advantagePatient statusPatientsTrialsDesign trialSignificant differencesObstructionOverdrainageInfection
1994
Time-related patterns of ventricular shunt failure
Kast J, Duong D, Nowzari F, Chadduck W, Schiff S. Time-related patterns of ventricular shunt failure. Child's Nervous System 1994, 10: 524-528. PMID: 7882375, DOI: 10.1007/bf00335075.Peer-Reviewed Original ResearchConceptsShunt failureVentricular shunt failureVentriculoperitoneal shunt failureAge of patientsCatheter placement techniqueVentricular catheter placementNovel valve systemDistal failureDistal malfunctionProximal malfunctionConsecutive patientsProximal obstructionShunt placementCatheter placementPrimary etiologyShunt revisionShunt malfunctionSite of failureTime-related patternOverall seriesProximal failureCommon causeOutcome studiesHigh incidencePatients