1995
Lymphocyte adhesion-dependent calcium signaling in human endothelial cells.
Pfau S, Leitenberg D, Rinder H, Smith BR, Pardi R, Bender JR. Lymphocyte adhesion-dependent calcium signaling in human endothelial cells. Journal Of Cell Biology 1995, 128: 969-978. PMID: 7533170, PMCID: PMC2120392, DOI: 10.1083/jcb.128.5.969.Peer-Reviewed Original ResearchConceptsEC Ca2Endothelial cellsEC alterationsLymphocyte-endothelial interactionsNatural killer cellsImmune effector cellsTumor necrosis factorHuman umbilical vein endothelial cellsCytosolic free calcium changesUmbilical vein endothelial cellsVascular endothelial cellsHuman umbilical vein ECsAllogeneic CD3Lymphocyte subsetsVein endothelial cellsHuman endothelial cellsNK cellsEffector cellsKiller cellsVascular toneInflammatory responseNecrosis factorSecond messenger pathwaysExtracellular influxCytokine activation
1993
Initiation of cardiac allograft rejection New developments in cellular and molecular mechanisms
Pfau S, Bender J. Initiation of cardiac allograft rejection New developments in cellular and molecular mechanisms. Trends In Cardiovascular Medicine 1993, 3: 196-203. PMID: 21244933, DOI: 10.1016/1050-1738(93)90006-r.Peer-Reviewed Original ResearchT cell activationEnd-stage heart diseaseEffective immunosuppressive therapyNatural killer lymphocytesImmune effector cellsViable therapeutic optionT lymphocyte recognitionT cell biologyEarly eventsCardiac transplantationImmunosuppressive therapyMedical complicationsEffector cellsTherapeutic optionsCytokine productionInflammatory cellsHeart diseaseKiller lymphocytesForeign antigensT cellsImmune responseClinical utilityVascular endotheliumRejection processLong-term success