Electronic cigarettes for adults with tobacco dependence enrolled in a tobacco treatment program: A pilot study
Baldassarri SR, Bernstein SL, Chupp GL, Slade MD, Fucito LM, Toll BA. Electronic cigarettes for adults with tobacco dependence enrolled in a tobacco treatment program: A pilot study. Addictive Behaviors 2017, 80: 1-5. PMID: 29304395, PMCID: PMC6463885, DOI: 10.1016/j.addbeh.2017.11.033.Peer-Reviewed Original ResearchConceptsTobacco treatment programTreatment-seeking smokersElectronic cigarettesWeek 24Tobacco treatmentTobacco smokersTreatment programTobacco treatment interventionsTobacco smokingPatch therapyTobacco dependenceEffective adjunctBehavioral counselingMean reductionSmokersSmoking outcomesTreatment settingsTreatment interventionsSmokingNicotine solutionPilot studyNicotineCigarettesSignificant differencesSubjectsUse of Electronic Cigarettes Leads to Significant Beta2-Nicotinic Acetylcholine Receptor Occupancy: Evidence From a PET Imaging Study
Baldassarri SR, Hillmer AT, Anderson JM, Jatlow P, Nabulsi N, Labaree D, Cosgrove KP, O’Malley S, Eissenberg T, Krishnan-Sarin S, Esterlis I. Use of Electronic Cigarettes Leads to Significant Beta2-Nicotinic Acetylcholine Receptor Occupancy: Evidence From a PET Imaging Study. Nicotine & Tobacco Research 2017, 20: 425-433. PMID: 28460123, PMCID: PMC5896427, DOI: 10.1093/ntr/ntx091.Peer-Reviewed Original ResearchConceptsBlood nicotine levelsAlternative nicotine delivery systemsNicotinic acetylcholine receptorsElectronic cigarettesNicotine delivery systemsCigarette smokersCigarette smokingTobacco cigarettesReceptor occupancyAbuse liabilityAcetylcholine receptorsNicotine levelsEC challengeCigarette smoking groupPositron emission tomography studyTobacco cigarette smokingEmission tomography studiesPET imaging studiesSmoking groupNeurologic effectsNicotine challengeNicotine addictionNicotine usersNovel radiotracersImaging studies