2021
Noninvasive detection of human dehydroepiandrosterone, progesterone and testosterone using LC-MS/MS revealed effects of birth control pills/devices and body weight on ovulatory prediction
Han L, Wemm SE, Shen L, Spink DC, Wulfert E, Cao ZT. Noninvasive detection of human dehydroepiandrosterone, progesterone and testosterone using LC-MS/MS revealed effects of birth control pills/devices and body weight on ovulatory prediction. Journal Of Chromatography B 2021, 1174: 122716. PMID: 33946036, DOI: 10.1016/j.jchromb.2021.122716.Peer-Reviewed Original Research
2019
Fluctuations in progesterone moderate the relationship between daily mood and alcohol use in young adult women
Holzhauer CG, Wemm SE, Wulfert E, Cao ZT. Fluctuations in progesterone moderate the relationship between daily mood and alcohol use in young adult women. Addictive Behaviors 2019, 101: 106146. PMID: 31639640, PMCID: PMC6876695, DOI: 10.1016/j.addbeh.2019.106146.Peer-Reviewed Original ResearchConceptsLevels of progesteroneYoung adult womenAlcohol useMenstrual cycleProgesterone levelsAdult womenDaily ratingsMenstrual cycle phaseDaily moodWomen's alcohol useOdds of drinkingProtective effectHormonal fluctuationsSalivary samplesPremenstrual phaseProgesteroneLow moodMood changesWomenLinear mixed modelsStandard deviation increaseTwo-week periodWeeksDaily logsMoodA day-by-day prospective analysis of stress, craving and risk of next day alcohol intake during alcohol use disorder treatment
Wemm SE, Larkin C, Hermes G, Tennen H, Sinha R. A day-by-day prospective analysis of stress, craving and risk of next day alcohol intake during alcohol use disorder treatment. Drug And Alcohol Dependence 2019, 204: 107569. PMID: 31574406, PMCID: PMC6916671, DOI: 10.1016/j.drugalcdep.2019.107569.Peer-Reviewed Original ResearchConceptsAlcohol use disorderAlcohol intakeEarly treatmentAlcohol use disorder treatmentStressful eventsNovel treatment approachesAlcohol relapse riskUse disorder treatmentNext dayWeeks of outpatientStress-induced cravingAlcohol use outcomesRelapse riskProspective analysisUse disordersAUD patientsTreatment approachesDisorder treatmentHigher cravingDaily diariesUse outcomesIntakeAUD individualsCravingDrinking amountNoninvasive determination of human cortisol and dehydroepiandrosterone sulfate using liquid chromatography-tandem mass spectrometry
Cao Z, Wemm SE, Han L, Spink DC, Wulfert E. Noninvasive determination of human cortisol and dehydroepiandrosterone sulfate using liquid chromatography-tandem mass spectrometry. Analytical And Bioanalytical Chemistry 2019, 411: 1203-1210. PMID: 30612174, DOI: 10.1007/s00216-018-1549-x.Peer-Reviewed Original ResearchConceptsLC-MS/MS methodLiquid chromatography-tandem mass spectrometryChromatography-tandem mass spectrometryHuman salivaMeasurement of steroidsPsychoneuroendocrinological researchSalivary DHEADHEACortisolSalivary cortisolSaliva samplesNoninvasive meansCortisol assayYoung adultsSteroidsRegression analysisSalivaMS methodPassive droolNoninvasive determinationHuman cortisolCommon steroidsMales
2018
Appetitive startle modulation in the human laboratory predicts Cannabis craving in the natural environment
Mereish EH, Padovano HT, Wemm S, Miranda R. Appetitive startle modulation in the human laboratory predicts Cannabis craving in the natural environment. Psychopharmacology 2018, 235: 1933-1943. PMID: 29623354, PMCID: PMC6015780, DOI: 10.1007/s00213-018-4890-z.Peer-Reviewed Original ResearchConceptsCue-elicited cravingStartle reactivityEcological momentary assessment protocolHuman laboratoryCannabis-related stimuliCannabis-related cuesFrequent cannabis usersCross-level interactionsCannabis cuesResultsMultilevel modelsDrug cuesMotivational processesResponse patternsMotivational systemsPicture cuesPleasant stimuliStartle modulationCannabis usersCannabis useCuesStartle magnitudeCravingReal-world environmentsAge 16Startle reflexPredictors of Topiramate Tolerability in Heavy Cannabis–Using Adolescents and Young Adults
Gray JC, Padovano H, Wemm SE, Miranda R. Predictors of Topiramate Tolerability in Heavy Cannabis–Using Adolescents and Young Adults. Journal Of Clinical Psychopharmacology 2018, 38: 134-137. PMID: 29424802, PMCID: PMC5825284, DOI: 10.1097/jcp.0000000000000843.Peer-Reviewed Original ResearchConceptsMemory difficultiesCannabis misuseYoung adultsPsychosocial treatment optionsSubstance use disordersPsychosocial interventionsCannabis problemsHeavy cannabisTreatment dropoutOverwhelming predictorPositive outcomesUse disordersEffective interventionsAdolescentsSide effectsMedication conditionRandomized placebo-controlled trialInteraction effectsSubstance abuse treatment admissionsTreatment admissionsPlacebo-controlled trialSecondary data analysisRecent clinical trialsIllicit drugsAdults
2017
Distress Tolerance and Physiological Reactivity to Stress Predict Women’s Problematic Alcohol Use
Holzhauer CG, Wemm S, Wulfert E. Distress Tolerance and Physiological Reactivity to Stress Predict Women’s Problematic Alcohol Use. Experimental And Clinical Psychopharmacology 2017, 25: 156-165. PMID: 28437123, DOI: 10.1037/pha0000116.Peer-Reviewed Original ResearchConceptsBehavioral distress toleranceDistress tolerancePhysiological reactivityStress reactivityAlcohol misuseNegative alcohol-related consequencesPhysiological stress reactivityAlcohol-related consequencesLow stress reactivityDrinking-related negative consequencesLower physiological reactivityWomen's alcohol misuseGreater urgeNonclinical sampleStressful taskYoung adult womenMeasures of reactivityCollege womenSubjective levelPrior findingsInteractive associationsAlcohol useNegative consequencesCurrent studyAdult womenEffects of Acute Stress on Decision Making
Wemm SE, Wulfert E. Effects of Acute Stress on Decision Making. Applied Psychophysiology And Biofeedback 2017, 42: 1-12. PMID: 28083720, PMCID: PMC5346059, DOI: 10.1007/s10484-016-9347-8.Peer-Reviewed Original ResearchConceptsHeart rateHigher heart rateSocial stressorsAcute stressSubstance useExploratory correlational analysesExploratory regression analysisMen’s higher levelsSkin conductance responsesRegression analysisIowa Gambling TaskStress respondingWomenControl conditionSkin conductancePhysiological reactivityConductance responsesFemale college studentsLow levelsGambling TaskParticipantsHigh levelsStressors
2013
Problematic drinking and physiological responses among female college students
Wemm S, Fanean A, Baker A, Blough ER, Mewaldt S, Bardi M. Problematic drinking and physiological responses among female college students. Alcohol 2013, 47: 149-157. PMID: 23333036, DOI: 10.1016/j.alcohol.2012.12.006.Peer-Reviewed Original ResearchConceptsProblematic drinkingLow DHEAS levelsImpaired physiological responseExcessive alcohol useCollege studentsHigher cortisol levelsHigh basal levelsMajority of participantsDHEAS levelsSalivary levelsBinge drinkingAdrenal activityCardiovascular measurementsAlcohol-related consequencesCortisol levelsBehavioral stress responsesAlcohol dependenceSelf-reported consequencesSelf-reported drinkingSaliva samplesAlcohol useBasal levelsFemale college studentsDistress tolerancePhysiological responses
2010
The role of DHEA in relation to problem solving and academic performance
Wemm S, Koone T, Blough ER, Mewaldt S, Bardi M. The role of DHEA in relation to problem solving and academic performance. Biological Psychology 2010, 85: 53-61. PMID: 20562010, DOI: 10.1016/j.biopsycho.2010.05.003.Peer-Reviewed Original ResearchConceptsGrade point averageAmerican College Testing (ACT) scoresCurrent grade point averageSets of anagramsTask demandsBehavioral tasksBehavioral flexibilityAcademic achievementMood disturbanceAcademic performanceProblem solvingCollege studentsPhysiological neuroprotectionPoint averageBehavioral responsesTaskTesting scoresCollege coursesParticipantsIndividualsAnagramsSame individualAnxietyChallenging taskHigh levels