Increase of serotypes 15A and 23B in IPD in Germany in the PCV13 vaccination era
van der Linden M, Perniciaro S, Imöhl M. Increase of serotypes 15A and 23B in IPD in Germany in the PCV13 vaccination era. BMC Infectious Diseases 2015, 15: 207. PMID: 25940580, PMCID: PMC4424534, DOI: 10.1186/s12879-015-0941-9.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseasePenicillin non-susceptible isolatesNon-PCV13 serotypesNon-susceptible isolatesSerotype 15AVaccination periodSurveillance of IPDClonal complexesChildhood pneumococcal conjugate vaccinationGerman National Reference CenterEarly vaccination periodHigher-valent vaccinesPneumococcal conjugate vaccinationNational Reference CenterConclusionsThe prevalenceConjugate vaccinationSerotype 23BPneumococcal diseaseChildhood vaccinationVaccination eraSurveillance periodSerogroups 23BackgroundThis studyReference centerVaccination formulationsPneumococcal meningitis and vaccine effects in the era of conjugate vaccination: results of 20 years of nationwide surveillance in Germany
Imöhl M, Möller J, Reinert R, Perniciaro S, van der Linden M, Aktas O. Pneumococcal meningitis and vaccine effects in the era of conjugate vaccination: results of 20 years of nationwide surveillance in Germany. BMC Infectious Diseases 2015, 15: 61. PMID: 25885764, PMCID: PMC4335684, DOI: 10.1186/s12879-015-0787-1.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseaseMeningitis casesPneumococcal meningitisQuellung reactionGerman National Reference CenterNeufeld Quellung reactionPre-PCV7 periodPneumococcal conjugate vaccinePost-vaccination periodCase mortality rateNational Reference CenterAntibiotic nonsusceptibilityIPD isolatesPneumococcal diseaseVaccination recommendationsVaccine recommendationsConjugate vaccineVaccine serotypesBroth microdilution methodVaccine effectsNationwide surveillancePneumococcal isolatesSerotype prevalenceReference centerMortality rate