Stephanie O'Malley, PhD
Elizabeth Mears and House Jameson Professor of PsychiatryDownloadHi-Res Photo
Cards
Appointments
Psychiatry
Primary
Additional Titles
Deputy Chair, Clinical Research
Contact Info
Psychiatry
Connecticut Mental Health Center - SAC 202, 34 Park Street
New Haven, CT 06508
United States
Appointments
Psychiatry
Primary
Additional Titles
Deputy Chair, Clinical Research
Contact Info
Psychiatry
Connecticut Mental Health Center - SAC 202, 34 Park Street
New Haven, CT 06508
United States
Appointments
Psychiatry
Primary
Additional Titles
Deputy Chair, Clinical Research
Contact Info
Psychiatry
Connecticut Mental Health Center - SAC 202, 34 Park Street
New Haven, CT 06508
United States
About
Titles
Elizabeth Mears and House Jameson Professor of Psychiatry
Deputy Chair, Clinical Research
Appointments
Psychiatry
ProfessorPrimary
Other Departments & Organizations
- ADVANCE Study
- Call it a Night
- Cancer Prevention and Control
- Center for Nicotine and Tobacco Use Research at Yale (CENTURY)
- Center for the Translational Neuroscience of Alcohol
- Connecticut Mental Health Center
- Division of Addictions
- Division of Substance Abuse
- Division of Women's Behavioral Health Research
- Neuroscience Research Training Program (NRTP)
- Psychiatry
- Psychology Section
- Psychotherapy Development Center
- Smoking Cessation and Alcohol Treatment Research Clinic
- Stress & Addiction Clinical Research Program
- Substance Abuse Research
- Tobacco Research in Youth (TRY)
- Yale Cancer Center
- Yale Medicine
- Yale Tobacco Center of Regulatory Science
- Yale Ventures
Education & Training
- PhD
- Vanderbilt University (1983)
- BS
- Vanderbilt University (1976)
Research
Overview
Yale Tobacco Center for Regulatory Science
Clinical trials of varenicline for the treatment of alcohol dependence among smokers and of naltrexone for young adult heavy drinkers
Laboratory studies to evaluate medications for substance use disorders
Validation of biomarkers for monitoring drinking in clinical trials
Secondary analyses to identify moderators and predictors of response to treatments for alcohol dependence using tree based and trajectory analyses
Training of clinician and transdisciplinary scientists
Medical Subject Headings (MeSH)
Alcoholism; Psychiatry; Psychiatry and Psychology; Risk Reduction Behavior; Smoking; Substance-Related Disorders
ORCID
0000-0003-0988-5522
Research at a Glance
Yale Co-Authors
Frequent collaborators of Stephanie O'Malley's published research.
Research Interests
Research topics Stephanie O'Malley is interested in exploring.
Krysten Bold, PhD
Suchitra Krishnan-Sarin, PhD
Meghan Morean, PhD
Ralitza Gueorguieva, PhD
Angela Haeny, PhD
Lisa Fucito, PhD
Publications
2024
Understanding use of e-cigarettes for smoking cessation among a sample of US adults
Sharma A, Morean M, Krishnan-Sarin S, O’Malley S, Bold K. Understanding use of e-cigarettes for smoking cessation among a sample of US adults. Nicotine & Tobacco Research 2024, ntae251. PMID: 39475073, DOI: 10.1093/ntr/ntae251.Peer-Reviewed Original ResearchConceptsQuit smokingNicotine replacement treatmentSmoking cessation aidE-cigarettesSmoking cessationCessation aidsSmoking cigarettesCessation attemptsSample of US adultsMajority of participantsSmoking cessation attemptsE-cigarette useComponents of e-cigarettesTime of surveyCessation supportUS adultsRegular cigarette smokingSmoking abstinenceRelapse rateNicotine patchSmokingReplacement treatmentNicotine-freeCigarette smokingOnline surveyA Digital Cognitive Behavioral Therapy Program for Adults With Alcohol Use Disorder
Kiluk B, Benitez B, DeVito E, Frankforter T, LaPaglia D, O’Malley S, Nich C. A Digital Cognitive Behavioral Therapy Program for Adults With Alcohol Use Disorder. JAMA Network Open 2024, 7: e2435205. PMID: 39325452, PMCID: PMC11428014, DOI: 10.1001/jamanetworkopen.2024.35205.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCognitive behavioral therapyDigital cognitive behavioral therapyAlcohol use disorderAlcohol useCBT programUse disorderCognitive behavioral therapy programCurrent alcohol use disorderTreatment-seeking adultsBehavioral therapy programEvidence-based treatmentsBaseline to 6-month follow-upRates of alcohol useReducing alcohol useTreatment periodRandomized clinical trialsBehavioral therapyOutpatient substancePercentage of daysOutpatient treatmentIntention-to-treat analysisIndividual counselingStudy periodFollow-upIntention-to-treatWords matter: descriptors for nicotine that comes from tobacco and descriptors for synthetic nicotine that is created in a laboratory differentially impact understanding of nicotine source and risk perceptions
Morean M, O'Malley S, Krishnan-Sarin S. Words matter: descriptors for nicotine that comes from tobacco and descriptors for synthetic nicotine that is created in a laboratory differentially impact understanding of nicotine source and risk perceptions. Tobacco Control 2024, tc-2024-058649. PMID: 39168594, DOI: 10.1136/tc-2024-058649.Peer-Reviewed Original ResearchThe Scientific Basis for the Regulation of Flavors in Tobacco Products
Bold K, Kong G, O'Malley S. The Scientific Basis for the Regulation of Flavors in Tobacco Products. Annual Review Of Clinical Psychology 2024, 20: 381-406. PMID: 38346292, PMCID: PMC11446566, DOI: 10.1146/annurev-clinpsy-080921-075624.Peer-Reviewed Original ResearchConceptsTobacco policiesTobacco productsTobacco useReduce tobacco-related health disparitiesTobacco-related health disparitiesFlavored tobacco productsMenthol tobacco productsHealth disparitiesFood and Drug AdministrationEvidence-based policyClinical research methodsMenthol cigarettesClinical sciencePublic healthTobaccoPopulation levelScientific evidencePublication dateRegulation of flavorClinical researchUS Food and Drug AdministrationProtect public healthAnnual ReviewExpected final online publication dateTobacco marketplaceEVALUATING THE FEASIBILITY AND PRELIMINARY EFFICACY OF A REAL-TIME SMOKING INTERVENTION USING WEARABLE TECHNOLOGY
Bold K, O'Malley S, Horvath M, Fucito L. EVALUATING THE FEASIBILITY AND PRELIMINARY EFFICACY OF A REAL-TIME SMOKING INTERVENTION USING WEARABLE TECHNOLOGY. Drug And Alcohol Dependence 2024, 260: 110062. DOI: 10.1016/j.drugalcdep.2023.110062.Peer-Reviewed Original ResearchConceptsSmartband-based smoking detection and real-time brief mindfulness intervention: findings from a feasibility clinical trial
Horvath M, Pittman B, O’Malley S, Grutman A, Khan N, Gueorguieva R, Brewer J, Garrison K. Smartband-based smoking detection and real-time brief mindfulness intervention: findings from a feasibility clinical trial. Annals Of Medicine 2024, 56: 2352803. PMID: 38823419, PMCID: PMC11146247, DOI: 10.1080/07853890.2024.2352803.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsBrief mindfulness interventionsMindfulness exercisesTreatment startersMindfulness interventionSmoking interventionsOnline mindfulness trainingWhite non-HispanicMindfulness trainingTreatment fidelityFeasibility measuresHelpfulness ratingsNon-HispanicDaily smokersPredicting smokingReduce smokingExerciseSmokingCigarette smokingInterventionLow completenessAdherenceParticipantsSmartbandAcceptanceMindfulnessHow healthcare providers and the right information may play a critical role in quitting success among smokers interested in using e-cigarettes for quitting: Results from a survey of U.S adults
Sharma A, King J, Krishnan-Sarin S, O’Malley S, Morean M, Bold K. How healthcare providers and the right information may play a critical role in quitting success among smokers interested in using e-cigarettes for quitting: Results from a survey of U.S adults. PLOS ONE 2024, 19: e0303245. PMID: 38753868, PMCID: PMC11098412, DOI: 10.1371/journal.pone.0303245.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsHealthcare providersQuit smokingE-cigarettesBenefits of e-cigarettesPromote smoking cessationPotential public health benefitsGlobal public health priorityPublic health priorityReduce cigarette smokingIncrease quit ratesSmoking cessation attemptsCessation supportNicotine concentrationsHealth prioritySource of informationQuit ratesUS adultsU.S adultsSmoking cessationQuit successCessation attemptsHealthcareProvidersSmokingCigarette smokingVarenicline for E-Cigarette Cessation in Adults: A Preliminary Placebo-Controlled Randomized Trial
Fucito L, Baldassarri S, Baker N, Palmer A, O'Malley S, Carpenter M, Krishnan-Sarin S, Gray K, Toll B. Varenicline for E-Cigarette Cessation in Adults: A Preliminary Placebo-Controlled Randomized Trial. American Journal Of Preventive Medicine 2024, 67: 296-298. PMID: 38752949, PMCID: PMC11260542, DOI: 10.1016/j.amepre.2024.04.007.Peer-Reviewed Original ResearchAltmetricEvidence that personalized racial stress procedures elicit a stress response and increases alcohol craving among Black adults with alcohol use disorder: A laboratory pilot study
Haeny A, Schick M, McKenley C, Chowdhary A, Bellamy C, O'Malley S, Sinha R. Evidence that personalized racial stress procedures elicit a stress response and increases alcohol craving among Black adults with alcohol use disorder: A laboratory pilot study. Drug And Alcohol Dependence 2024, 260: 111312. PMID: 38749311, DOI: 10.1016/j.drugalcdep.2024.111312.Peer-Reviewed Original ResearchAltmetricConceptsAlcohol use disorderAlcohol cravingIncreased alcohol cravingUse disorderRacial stressEmotional responsesImpact of racial stressBlack adultsExposure to stressStress scriptsImagery procedureExposure sessionsCravingPersonal eventsStress procedureNegative emotionsNeutral conditionsPositive emotionsIdentity explorationStress responseExploratory analysisPhysiological responsesSessionsEmotionsAlcoholReductions in World Health Organization risk drinking level are associated with improvements in sleep problems among individuals with alcohol use disorder
Garcia C, Richards D, Tuchman F, Hallgren K, Kranzler H, Aubin H, O’Malley S, Mann K, Aldridge A, Hoffman M, Anton R, Witkiewitz K. Reductions in World Health Organization risk drinking level are associated with improvements in sleep problems among individuals with alcohol use disorder. Alcohol And Alcoholism 2024, 59: agae022. PMID: 38606931, PMCID: PMC11010310, DOI: 10.1093/alcalc/agae022.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsAlcohol use disorderSleep problemsAssociated with improvementsUse disorderMaintenance of alcohol use disorderDrinking levelsWorld Health Organization risk drinking levelsRisk drinking levelsTimeline Follow-BackSleep problem scoreFewer sleep problemsMonths of treatmentDrinking reductionFollow-backPittsburgh Sleep Quality IndexActive medicationSleep Quality IndexProblem scoresExtended-releaseAlcohol usePlacebo groupSleep disturbanceHarm reduction approachesSleep qualityControlled trials
Clinical Trials
Current Trials
Brief training for 18-26 year olds: Regulation of alcohol craving
HIC ID2000029394RoleSub InvestigatorPrimary Completion Date12/31/2022Recruiting ParticipantsGenderBothAge18 years - 26 yearsVarenicline for treatment of e-cigarette dependence
HIC ID2000032740RoleSub InvestigatorPrimary Completion Date09/30/2023Recruiting ParticipantsGenderBothAge18+ yearsThe interaction of flavor with nicotine form in adult smokers
HIC ID2000025687RoleSub InvestigatorPrimary Completion Date05/31/2022Recruiting ParticipantsGenderBothAge21+ years
Academic Achievements & Community Involvement
activity Alcoholism:Clinical and Experimental Research
Professional OrganizationsMemberDetailsSenior Advisory Board2011 - Presentactivity American College of Neuropsychopharmacology/American Society of Clinical Psychopharmacology
Professional OrganizationsMemberDetailsWorking group on alcohol medication trial design2008 - Presentactivity Psychiatry Investigation
Professional OrganizationsMemberDetailsEditorial Board2004 - Presentactivity JAMA Psychiatry
Professional OrganizationsMemberDetailsEditorial Board2015 - Presentactivity NIDA
CommitteesMemberDetailsData Safety Monitoring Board, Clinical Trials Network2015 - Present
News & Links
News
- September 26, 2024
Yale Study: Digital Cognitive Behavioral Therapy Program Found More Effective Than Clinician-Delivered Therapy at Reducing Alcohol Use in a Clinical Trial
- June 03, 2024Source: Scientific American
How Tobacco Companies Use Chemistry To Get Around Menthol Bans
- September 27, 2023
$20M Federal Grant Renewed for Yale Tobacco Center of Regulatory Science
- April 10, 2023
Fucito, DeMartini Awarded Grant by NIAAA
Get In Touch
Contacts
Mailing Address
Psychiatry
Connecticut Mental Health Center - SAC 202, 34 Park Street
New Haven, CT 06508
United States