Mitotic Regulation of Ribosomal S6 Kinase 1 Involves Ser/Thr, Pro Phosphorylation of Consensus and Non-consensus Sites by Cdc2*
Shah OJ, Ghosh S, Hunter T. Mitotic Regulation of Ribosomal S6 Kinase 1 Involves Ser/Thr, Pro Phosphorylation of Consensus and Non-consensus Sites by Cdc2*. Journal Of Biological Chemistry 2003, 278: 16433-16442. PMID: 12586835, DOI: 10.1074/jbc.m300435200.Peer-Reviewed Original ResearchConceptsSer/ThrMultiple Ser/ThrRibosomal S6 kinase 1Hydrophobic motif siteRibosomal protein mRNAsRNA polymerase IIProline-directed phosphorylationRibosomal protein synthesisPhosphorylation of S6K1S6 kinase 1Mitotic HeLa cellsCyclin-dependent kinasesActivity of cdc2Elongation factor 1gammaNon-consensus sitesRibosome biogenesisMitotic regulationPolymerase IIPhosphorylation sitesMRNA processingMotif sitesProtein kinaseTriggers inactivationMitotic processesCyclin B