2014
The Immune System and Electroconvulsive Therapy for Depression
Guloksuz S, Rutten B, Arts B, van Os J, Kenis G. The Immune System and Electroconvulsive Therapy for Depression. Journal Of Ect 2014, 30: 132-137. PMID: 24755720, DOI: 10.1097/yct.0000000000000127.Peer-Reviewed Original ResearchConceptsEffects of ECTElectroconvulsive therapyImmune systemMechanism of actionImmune activationImmune functioningImpact of ECTTherapeutic actionTreatment-resistant depressionTransient immune activationPubMed/MEDLINEPossible roleImmunological changesCytokine concentrationsAdrenal axisTreatment optionsLarger sample sizeTreatment resultsPsychiatric conditionsSingle sessionRelevant articlesDefinitive conclusionsSearch termsSample sizeDepression
2013
Depressive Symptoms in Crohn's Disease: Relationship with Immune Activation and Tryptophan Availability
Guloksuz S, Wichers M, Kenis G, Russel M, Wauters A, Verkerk R, Arts B, van Os J. Depressive Symptoms in Crohn's Disease: Relationship with Immune Activation and Tryptophan Availability. PLOS ONE 2013, 8: e60435. PMID: 23544139, PMCID: PMC3609785, DOI: 10.1371/journal.pone.0060435.Peer-Reviewed Original ResearchConceptsCrohn's diseaseDisease activityImmune activationDepressive symptomsDepression scoresTrp availabilityΑ treatmentTryptophan availabilityNegative APPsAnti-tumor necrosis factorPast depressive disorderTNF-α treatmentSymptoms of depressionQuality of lifeCD patientsIBDQ scoreImmune markersComorbid depressionDepressive disorderNecrosis factorInflammatory reactionPatientsSymptomsDiseaseTreatment