2024
The relationship between childhood trauma, psychotic symptoms, and cognitive schemas in patients with schizophrenia, their siblings, and healthy controls: results from the EU-GEI study.
Üçok A, Noyan H, Gülöksüz S, Saka M, Alptekin K, Atbaşoğlu C, Akturan E, Karadayı G, Baran Tatar Z, Akdede B, Binbay T, Altınyazar V, Ulaş H, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Şahin Cankurtaran E, Ulusoy Kaymak S, Rutten B, van Os J. The relationship between childhood trauma, psychotic symptoms, and cognitive schemas in patients with schizophrenia, their siblings, and healthy controls: results from the EU-GEI study. Psychological Medicine 2024, 54: 2414-2425. PMID: 38606591, DOI: 10.1017/s0033291724000540.Peer-Reviewed Original ResearchNegative cognitive schemasChildhood traumaCognitive schemasPsychotic symptomsEU-GEIEmotional abuseBrief Core Schema ScalesEU-GEI studySubthreshold psychotic experiencesSubtypes of traumaChildhood emotional abuseChildhood Trauma QuestionnaireNon-clinical populationsHealthy controlsNegative schemasPositive symptomsPersecutory delusionsPsychotic experiencesSchema ScaleTrauma QuestionnaireChildhood abuseSymptom severitySchizophreniaSexual abuseAbuse
2023
Gender differences in the associations between childhood adversity and psychopathology in the general population
Prachason T, Mutlu I, Fusar-Poli L, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, van Os J, Rutten B, Pries L, Guloksuz S. Gender differences in the associations between childhood adversity and psychopathology in the general population. Social Psychiatry And Psychiatric Epidemiology 2023, 59: 847-858. PMID: 37624463, PMCID: PMC11087312, DOI: 10.1007/s00127-023-02546-5.Peer-Reviewed Original ResearchSCL-90Interpersonal sensitivityPhobic anxietyEmotional neglectEmotional abuseSexual abusePhysical neglectSymptom domainsGender differencesChildhood Trauma QuestionnaireSymptom Checklist-90Paranoid ideationSignificant gender differencesTrauma QuestionnaireChildhood adversityPsychopathologyDifferential associationsOverall psychopathologyAnxietySymptom domain scoresPsychiatric symptomsAbuseNeglectExploratory analysisDomain scoresDifferential associations of childhood adversity subtypes and psychopathology in men and women
Prachason T, Mutlu I, Fusar-Poli L, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, van Os J, Rutten B, Pries L, Gülöksüz S. Differential associations of childhood adversity subtypes and psychopathology in men and women. European Psychiatry 2023, 66: s80-s81. PMCID: PMC10596228, DOI: 10.1192/j.eurpsy.2023.254.Peer-Reviewed Original ResearchChildhood Trauma QuestionnaireSymptom domainsSCL-90Emotional neglectEmotional abuseSexual abusePhysical neglectChildhood adversityDisclosure of interestPsychiatric symptomsSymptom Checklist-90Total CTQ scoresGender-specific influenceSCL-90 scoresGender-specific associationsDiverse psychopathologiesSignificant gender differencesTrauma QuestionnaireCTQ scoresDifferential associationsPsychopathologySymptom domain scoresGender differencesCA exposureSubdomain scores
2020
Polygenic liability for schizophrenia and childhood adversity influences daily‐life emotion dysregulation and psychosis proneness
Pries L, Klingenberg B, Menne‐Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, Cinar O, Lin B, Luykx J, Rutten B, van Os J, Guloksuz S. Polygenic liability for schizophrenia and childhood adversity influences daily‐life emotion dysregulation and psychosis proneness. Acta Psychiatrica Scandinavica 2020, 141: 465-475. PMID: 32027017, PMCID: PMC7318228, DOI: 10.1111/acps.13158.Peer-Reviewed Original ResearchConceptsDaily life stressorsChildhood adversityEmotion dysregulationPositive affectPsychosis pronenessMomentary mental statesEcological momentary assessmentChildhood Trauma QuestionnaireGene-environment correlationNegative affectMental statesMomentary assessmentPsychosis expressionTrauma QuestionnaireAdversityAffectYoung adultsStressorsNovel evidencePolygenic liabilityInteraction effectsPronenessSchizophreniaHigh PRSState domain
2011
P01-239 - The effects of childhood trauma on psychotic symptoms in bipolar disorder
Ozkose M, Guclu O, Guloksuz S, Karaca O, Yildirim B, Ince B, Erkmen H. P01-239 - The effects of childhood trauma on psychotic symptoms in bipolar disorder. European Psychiatry 2011, 26: 240. DOI: 10.1016/s0924-9338(11)71950-2.Peer-Reviewed Original ResearchYoung Mania Rating ScaleMontgomery-Asperg Depression Rating ScalePsychotic episodeBipolar patientsBipolar disorderChildhood Trauma QuestionnaireChildhood traumaPsychotic symptomsRating ScaleDuration of illnessSexual abuse scoresDepression Rating ScaleMania Rating ScaleStandard treatment planTerms of ageAbuse scoresDSM-IV-TRBakirkoy ResearchInpatient unitPatientsTraining hospitalsPhysical abuse scoresPositive symptomsTherapeutic interventionsTreatment plan