2016
ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells
Boddupalli CS, Nair S, Gray SM, Nowyhed HN, Verma R, Gibson JA, Abraham C, Narayan D, Vasquez J, Hedrick CC, Flavell RA, Dhodapkar KM, Kaech SM, Dhodapkar MV. ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells. Journal Of Clinical Investigation 2016, 126: 3905-3916. PMID: 27617863, PMCID: PMC5096804, DOI: 10.1172/jci85329.Peer-Reviewed Original ResearchConceptsTissue-resident memory T cellsMemory T cellsT cellsTRM cellsCellular therapyAdoptive cellular therapyImmune-deficient micePotential cellular therapySP T cellsSide population cellsHuman T cellsPutative subsetsAdoptive transferDistinct gene expression profilesCell mobilizationImmune surveillanceQuiescent subsetPopulation cellsMiceTherapyQuiescent phenotypeDistinct subsetsMember 1Nuclear receptorsSignature genes
2008
Association of Strong Immune Responses to PPE Protein Rv1168c with Active Tuberculosis ▿
Khan N, Alam K, Nair S, Valluri VL, Murthy KJ, Mukhopadhyay S. Association of Strong Immune Responses to PPE Protein Rv1168c with Active Tuberculosis ▿. MSphere 2008, 15: 974-980. PMID: 18400969, PMCID: PMC2446626, DOI: 10.1128/cvi.00485-07.Peer-Reviewed Original ResearchConceptsTB patientsESAT-6Sensitized peripheral blood mononuclear cellsStrong gamma interferon responseSmear-negative pulmonary TBPeripheral blood mononuclear cellsExtrapulmonary TB casesSerodiagnosis of TBBlood mononuclear cellsPotent T-cell antigenControl of TBT-cell antigensGamma interferon responseStrong immune responseConventional diagnostic testsConventional enzyme immunoassayActive TBMycobacterium bovis BCGPulmonary TBActive tuberculosisTB casesTuberculosis infectionMononuclear cellsImmune responseStrong immunoreactivity