2022
Why language matters in alcohol research: Reducing stigma
Shi HD, McKee SA, Cosgrove KP. Why language matters in alcohol research: Reducing stigma. Alcohol Clinical And Experimental Research 2022, 46: 1103-1109. PMID: 35727299, PMCID: PMC9246863, DOI: 10.1111/acer.14840.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismBehavior, AddictiveHumansLanguageNational Institutes of Health (U.S.)Social StigmaTerminology as TopicUnited StatesConceptsAlcohol use disorderUse disordersTreatment outcomesPubMed CentralDrug use disordersQuality of careRate of treatmentAlcohol research communityManual searchWiley Online DatabaseAddictive disordersDisordersTreatment seekingAlcoholicsNational InstituteNIH fundingPercent useInternational SocietyTerminology guidelinesStigmatizing languageAlcohol researchStigmatizing mannerOutcomes
2017
Targeting Stress Neuroadaptations for Addiction Treatment: A Commentary on Kaye et al. (2017).
Verplaetse TL, McKee SA. Targeting Stress Neuroadaptations for Addiction Treatment: A Commentary on Kaye et al. (2017). Journal Of Studies On Alcohol And Drugs 2017, 78: 372-374. PMID: 28499101, PMCID: PMC5440362, DOI: 10.15288/jsad.2017.78.372.Peer-Reviewed Original ResearchBehavior, AddictiveHumans
2016
An overview of alcohol and tobacco/nicotine interactions in the human laboratory
Verplaetse TL, McKee SA. An overview of alcohol and tobacco/nicotine interactions in the human laboratory. The American Journal Of Drug And Alcohol Abuse 2016, 43: 186-196. PMID: 27439453, PMCID: PMC5588903, DOI: 10.1080/00952990.2016.1189927.Peer-Reviewed Original ResearchConceptsAlcohol-tobacco interactionsNicotine interactionsHuman laboratorySubjective responsesBlood alcohol curveDrinking cuesAlcohol use disorderOverview of alcoholNicotine deprivationSelf-administration behaviorDrugs of abuseAlcohol cravingReciprocal influenceAlcohol curveAlcohol influenceSubjective effectsUse disordersTobacco/nicotineNicotine administrationTobacco useInteractive effectsCravingMajor public health concernPublic health concernDrinkers
2012
Sex Differences in Availability of β2*-Nicotinic Acetylcholine Receptors in Recently Abstinent Tobacco Smokers
Cosgrove KP, Esterlis I, McKee SA, Bois F, Seibyl JP, Mazure CM, Krishnan-Sarin S, Staley JK, Picciotto MR, O’Malley S. Sex Differences in Availability of β2*-Nicotinic Acetylcholine Receptors in Recently Abstinent Tobacco Smokers. JAMA Psychiatry 2012, 69: 418-427. PMID: 22474108, PMCID: PMC3508698, DOI: 10.1001/archgenpsychiatry.2011.1465.Peer-Reviewed Original ResearchMeSH KeywordsAdultAzetidinesBehavior, AddictiveBrainDepressionEstradiolFemaleFunctional NeuroimagingHumansIodine RadioisotopesMaleNicotinic AntagonistsProgesteronePyridinesRadioligand AssayReceptors, NicotinicSex CharacteristicsSmokingSubstance Withdrawal SyndromeTomography, Emission-Computed, Single-PhotonConceptsNAChR availabilityFemale smokersTobacco smokersNicotinic acetylcholine receptorsFemale nonsmokersProgesterone levelsAcetylcholine receptorsFemale sex steroid hormonesSex differencesSex steroid hormone levelsAbstinent tobacco smokersSex-matched nonsmokersTobacco smoking effectsMagnetic resonance imaging studyAge-matched malesEquilibrium distribution volumeEffects of nicotineSex steroid hormonesSteroid hormone levelsUnderlying neurochemical mechanismsResonance imaging studySingle photon emissionDays of abstinenceIA SPECTNicotine therapy
2011
Blunted vagal reactivity predicts stress-precipitated tobacco smoking
Ashare RL, Sinha R, Lampert R, Weinberger AH, Anderson GM, Lavery ME, Yanagisawa K, McKee SA. Blunted vagal reactivity predicts stress-precipitated tobacco smoking. Psychopharmacology 2011, 220: 259-268. PMID: 21938416, PMCID: PMC3260347, DOI: 10.1007/s00213-011-2473-3.Peer-Reviewed Original ResearchConceptsAd lib smokingLF/HFVagal reactivityHF-HRVAbstinent smokersVagal toneSmoking behaviorSmoking cessation outcomesHigh-frequency heart rate variabilityHigh-frequency HRVBaseline HF-HRVHeart rate variabilityScript-driven imageryAltered stress responseTobacco smokingAutonomic functionConclusionsThe current findingsCessation outcomesSympathovagal balanceSmokingRate variabilityAutonomic reactivitySmokersRelapseCurrent findings
2010
Brain β2*-nicotinic acetylcholine receptor occupancy after use of a nicotine inhaler
Esterlis I, Mitsis EM, Batis JC, Bois F, Picciotto MR, Stiklus SM, Kloczynski T, Perry E, Seibyl JP, McKee S, Staley JK, Cosgrove KP. Brain β2*-nicotinic acetylcholine receptor occupancy after use of a nicotine inhaler. The International Journal Of Neuropsychopharmacology 2010, 14: 389-398. PMID: 21029513, PMCID: PMC3510008, DOI: 10.1017/s1461145710001227.Peer-Reviewed Original ResearchConceptsNicotine inhalerWithdrawal symptomsReceptor occupancyTobacco smokingLow nicotine cigarettesAdministration of nicotineHigh receptor occupancyDoses of nicotineNicotinic acetylcholine receptorsInhaler useTobacco smokersBaseline scanRegular cigarettesInhalerConstant infusionAcetylcholine receptorsSPECT studiesCigarettesSymptomsBeta 2Significant decreaseNicotineSignificant differencesSmokingNAChRsStress decreases the ability to resist smoking and potentiates smoking intensity and reward
McKee SA, Sinha R, Weinberger AH, Sofuoglu M, Harrison E, Lavery M, Wanzer J. Stress decreases the ability to resist smoking and potentiates smoking intensity and reward. Journal Of Psychopharmacology 2010, 25: 490-502. PMID: 20817750, PMCID: PMC3637660, DOI: 10.1177/0269881110376694.Peer-Reviewed Original ResearchConceptsSelf-administration sessionsFirst cigaretteTobacco cravingNovel human laboratory modelAdrenal (HPA) axis reactivitySmoking lapse behaviorHuman laboratory modelImpact of stressNegative emotionsTobacco relapseDaily smokersSubsequent smokingImagery inductionAxis reactivitySmokingSubjects designSeparate daysPhysiologic reactivityMonetary reinforcementLapse behaviorTopography systemRelapseGreater satisfactionReduced abilityStress induction
2009
Effects of the nicotinic receptor antagonist mecamylamine on ad-lib smoking behavior, topography, and nicotine levels in smokers with and without schizophrenia: A preliminary study
McKee SA, Weinberger AH, Harrison EL, Coppola S, George TP. Effects of the nicotinic receptor antagonist mecamylamine on ad-lib smoking behavior, topography, and nicotine levels in smokers with and without schizophrenia: A preliminary study. Schizophrenia Research 2009, 115: 317-324. PMID: 19700263, PMCID: PMC2784178, DOI: 10.1016/j.schres.2009.07.019.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBehavior, AddictiveDouble-Blind MethodFemaleHumansMaleMecamylamineMiddle AgedNeuropsychological TestsNicotinic AntagonistsReaction TimeSchizophreniaSelf AdministrationSmokingSmoking CessationSubstance Withdrawal SyndromeSurveys and QuestionnairesTobacco Use DisorderYoung AdultConceptsAd lib smoking behaviorNicotine levelsSmoking behaviorControl smokersSmoking topographyNicotinic receptor antagonist mecamylamineNicotinic acetylcholine receptor antagonistHealthy control smokersHigh-affinity nAChRsIntensity of smokingAd lib smokingEffects of mecamylamineNumber of cigarettesPlacebo-controlled designAcetylcholine receptor antagonistNicotine exposureAntagonist mecamylamineCompensatory smokingReceptor antagonistSmoking intensityMecamylamineSmokersSmokingSchizophreniaPreliminary study
2008
Message Framing for Smoking Cessation: The Interaction of Risk Perceptions and Gender
Toll BA, Salovey P, O'Malley SS, Mazure CM, Latimer A, McKee SA. Message Framing for Smoking Cessation: The Interaction of Risk Perceptions and Gender. Nicotine & Tobacco Research 2008, 10: 195-200. PMID: 18188760, PMCID: PMC2527723, DOI: 10.1080/14622200701767803.Peer-Reviewed Original ResearchConceptsMessage framing interventionsRisk of cessationSmoking cessationLung cancerClinical trialsGain-framed messagesHigh riskSmoking relapseHealth message framingHealth problemsLoss-framed messagesSmokingFraming interventionCessationNumber of daysInfluence of genderInterventionRiskRisk perceptionWomenMedian splitGain-framed conditionDaysMenGender differences
2006
Modeling the effect of alcohol on smoking lapse behavior
McKee SA, Krishnan-Sarin S, Shi J, Mase T, O’Malley S. Modeling the effect of alcohol on smoking lapse behavior. Psychopharmacology 2006, 189: 201-210. PMID: 17013640, PMCID: PMC2862311, DOI: 10.1007/s00213-006-0551-8.Peer-Reviewed Original ResearchConceptsFirst cigaretteSelf-administration sessionsNovel human laboratory modelPoor smoking cessation outcomesSmoking cessation outcomesSmoking lapse behaviorHuman laboratory modelEffects of alcoholSecondary outcomesAlcohol drinkersLapse behaviorMore cigarettesNicotine withdrawalCessation outcomesRisk factorsDaily smokersSubsequent smokingTobacco cravingPlacebo beverageTobacco relapseSmoking sessionHeavy social drinkersPriming drinkAlcohol consumptionAlcohol use
2005
Investigating the factor structure of the Questionnaire on Smoking Urges-Brief (QSU-Brief)
Toll BA, Katulak NA, McKee SA. Investigating the factor structure of the Questionnaire on Smoking Urges-Brief (QSU-Brief). Addictive Behaviors 2005, 31: 1231-1239. PMID: 16226843, PMCID: PMC2527734, DOI: 10.1016/j.addbeh.2005.09.008.Peer-Reviewed Original ResearchConceptsSmoking Urges-BriefTreatment-seeking populationQSU-BriefSmoking urgesGood internal consistency reliability estimateStudy sampleFive-itemTwo-factor structurePsychometric propertiesPresent studyQuestionnaireInitial exploratory factor analysisInternal consistency reliability estimatesFactor analysisExploratory factor analysisFactor analytic findingsReliable assessmentSmokersScoringConfirmatory factor analysis
2003
Effects of an Implicit Mood Prime on the Accessibility of Smoking Expectancies in College Women
McKee SA, Wall AM, Hinson RE, Goldstein A, Bissonnette M. Effects of an Implicit Mood Prime on the Accessibility of Smoking Expectancies in College Women. Psychology Of Addictive Behaviors 2003, 17: 219-225. PMID: 14498816, DOI: 10.1037/0893-164x.17.3.219.Peer-Reviewed Original ResearchConceptsSmoking expectanciesNegative reinforcementNegative reinforcement expectanciesMusical mood inductionMusic control conditionMemory-based modelsSituational specificity hypothesisMood inductionReinforcement expectanciesPositive reinforcementCollege womenControl conditionSmoking behaviorAffectExpectancyPrimesStimuliReinforcementParticipantsSmokersExpectationsHypothesis