2021
Sex Differences across Retrospective Transitions in Posttraumatic Stress and Substance Use Disorders
Peltier MR, Roberts W, Verplaetse TL, Zakiniaeiz Y, Burke C, Moore KE, McKee SA. Sex Differences across Retrospective Transitions in Posttraumatic Stress and Substance Use Disorders. Journal Of Dual Diagnosis 2021, 18: 11-20. PMID: 34965199, PMCID: PMC9086923, DOI: 10.1080/15504263.2021.2016027.Peer-Reviewed Original ResearchConceptsDrug use disordersOngoing posttraumatic stress disorderSubstance use disordersSUD/PTSDPosttraumatic stress disorderNew PTSD diagnosisImpact of sexUse disordersDiagnosis of SUDPast-year substance use disorderPTSD diagnosisConcurrent substance use disordersDiagnosis of PTSDPoor treatment outcomesNational Epidemiologic SurveyBidirectional relationshipSex-specific analysesPotential sex-specific differencesTreatment outcomesChanges in alcohol use by cannabis use status among adolescents and young adults in the United States: Emerging evidence for both substitution and complementarity
Weinberger AH, Zhu J, Levin J, Moeller SJ, McKee SA, Goodwin RD. Changes in alcohol use by cannabis use status among adolescents and young adults in the United States: Emerging evidence for both substitution and complementarity. Alcohol Clinical And Experimental Research 2021, 45: 2536-2545. PMID: 34928520, PMCID: PMC8742181, DOI: 10.1111/acer.14737.Peer-Reviewed Original ResearchConceptsDaily alcohol useCannabis useAlcohol useYoung adultsAge 12Health (NSDUH) public use data filesPublic Use Data FilePast-month cannabisLogistic regression modelsRecent cannabis useMajority of adolescentsAverage drinksRate of declineDrug useAYAsPast month alcohol useAlcohol drinksAverage alcoholAnalytic sampleCannabisRecent cannabisCannabis legalizationNational surveyUnited StatesCurrent dataPsychosocial function, legal involvement and violence in mental disorder
Buchanan A, Moore KE, Pittman B, McKee SA. Psychosocial function, legal involvement and violence in mental disorder. European Psychiatry 2021, 64: e75. PMID: 34859762, PMCID: PMC8715282, DOI: 10.1192/j.eurpsy.2021.2250.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismComorbidityDiagnostic and Statistical Manual of Mental DisordersHumansMental DisordersViolenceConceptsPsychosocial functionAssociated Disabilities Interview Schedule-5Mental disordersWorse psychosocial functionDSM-5 categoriesAlcohol use disorderLongitudinal designSchedule 5Significant outcomesLegal involvementUse disordersPersonality disorderEffect sizeDrug abuseNational Epidemiologic SurveyAlcohol abuseMental illnessDisordersAbuseLifetime outcomesPeopleRepresentative sampleRelated conditionsSocial networksForm Health Survey version 2
2019
Alcohol Abstainer Status and Prazosin Treatment in Association with Changes in Posttraumatic Stress Disorder Symptoms in Veterans with Comorbid Alcohol Use Disorder and Posttraumatic Stress Disorder
Verplaetse TL, Ralevski E, Roberts W, Gueorguieva R, McKee SA, Petrakis IL. Alcohol Abstainer Status and Prazosin Treatment in Association with Changes in Posttraumatic Stress Disorder Symptoms in Veterans with Comorbid Alcohol Use Disorder and Posttraumatic Stress Disorder. Alcohol Clinical And Experimental Research 2019, 43: 741-746. PMID: 30698839, PMCID: PMC6443463, DOI: 10.1111/acer.13969.Peer-Reviewed Original ResearchConceptsAlcohol use disorderPosttraumatic stress disorderPlacebo-treated individualsTotal CAPS scoresClinical trialsCAPS scoresPrazosin treatmentComorbid populationPTSD symptomsUse disordersClinician-Administered PTSD Scale scoresDouble-blind clinical trialStress disorderComorbid alcohol use disorderPrazosin-treated groupSymptoms of PTSDRecent clinical trialsComorbid alcohol dependenceCourse of treatmentΑ1-adrenergic antagonistPosttraumatic stress disorder (PTSD) symptomsOngoing symptomsSleep disturbancesMedication effectsNoradrenergic systemPsychiatric Disorders and Crime in the US Population: Results From the National Epidemiologic Survey on Alcohol and Related Conditions Wave III.
Moore KE, Oberleitner LMS, Zonana HV, Buchanan AW, Pittman BP, Verplaetse TL, Angarita GA, Roberts W, McKee SA. Psychiatric Disorders and Crime in the US Population: Results From the National Epidemiologic Survey on Alcohol and Related Conditions Wave III. The Journal Of Clinical Psychiatry 2019, 80 PMID: 30758921, PMCID: PMC7826201, DOI: 10.4088/jcp.18m12317.Peer-Reviewed Original ResearchHigh Risk of Alcohol-Impaired Driving in Adults With Comorbid Alcohol and Substance Use Disorders in the U.S. Population.
Roberts W, Moore KE, Pittman BP, Fillmore MT, McKee SA. High Risk of Alcohol-Impaired Driving in Adults With Comorbid Alcohol and Substance Use Disorders in the U.S. Population. Journal Of Studies On Alcohol And Drugs 2019, 80: 114-119. PMID: 30807283, PMCID: PMC6396510, DOI: 10.15288/jsad.2019.80.114.Peer-Reviewed Original ResearchConceptsSubstance use disordersAlcohol use disorderComorbid substance use disorderUse disordersSUD diagnosisHigh riskAssociated Disabilities Interview Schedule-5Alcohol-impaired drivingPast-year alcohol use disorderSubstance use comorbiditiesNational Epidemiologic SurveyDSM-5 criteriaAlcohol-impaired driving behaviorIncreased oddsComorbid alcoholQuantity/frequencyHigher oddsPast-year drinkersEpidemiologic SurveyRelated conditionsAUD severityU.S. populationDisordersOddsCannabis legalization
2018
Effects of Varenicline Alone and in Combination With Low-dose Naltrexone on Alcohol-primed Smoking in Heavy-drinking Tobacco Users
Roberts W, Shi JM, Tetrault JM, McKee SA. Effects of Varenicline Alone and in Combination With Low-dose Naltrexone on Alcohol-primed Smoking in Heavy-drinking Tobacco Users. Journal Of Addiction Medicine 2018, 12: 227-233. PMID: 29438157, PMCID: PMC5970035, DOI: 10.1097/adm.0000000000000392.Peer-Reviewed Original ResearchConceptsLow-dose naltrexoneTobacco usersTreatment outcomesPlacebo-controlled human laboratory studySmoking cessation treatmentEffects of vareniclineCigarettes ad libitumHuman laboratory studiesSubjective drug effectsVarenicline monotherapyCessation medicationsMedication therapyCessation treatmentMedication armTobacco useVareniclineLow doseSmoking relapseSmokingDrug effectsSmoking outcomesSmoking behaviorNaltrexoneCarbon monoxide levelsHeavy drinkersPharmacotherapy for Co-Occurring Alcohol Use Disorder and Post-Traumatic Stress Disorder: Targeting the Opioidergic, Noradrenergic, Serotonergic, and GABAergic/Glutamatergic Systems.
Verplaetse TL, McKee SA, Petrakis IL. Pharmacotherapy for Co-Occurring Alcohol Use Disorder and Post-Traumatic Stress Disorder: Targeting the Opioidergic, Noradrenergic, Serotonergic, and GABAergic/Glutamatergic Systems. Alcohol Research 2018, 39: 193-205. PMID: 31198658, PMCID: PMC6561397.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismBrainComorbidityHumansNeurotransmitter AgentsStress Disorders, Post-TraumaticConceptsPost-traumatic stress disorderCo-occurring alcohol use disorderAlcohol use disorderComorbid alcohol use disorderStress disorderNeurobiological systemsMaintenance of AUDUse disordersPTSD symptom severityAlcohol-motivated behaviorsAlcohol use outcomesPharmacologic treatment strategiesBrain systemsTreatment of individualsCurrent medicationsComorbid populationGlutamatergic systemPotential pharmacotherapyPharmacologic interventionsUse outcomesTreatment outcomesTreatment strategiesSingular diagnosisDual diagnosisTreatment interventions
2017
Effects of varenicline on alcohol self-administration and craving in drinkers with depressive symptoms
Roberts W, Verplaetse TL, Moore K, Oberleitner L, Picciotto MR, McKee SA. Effects of varenicline on alcohol self-administration and craving in drinkers with depressive symptoms. Journal Of Psychopharmacology 2017, 31: 906-914. PMID: 28351203, PMCID: PMC5823265, DOI: 10.1177/0269881117699618.Peer-Reviewed Original ResearchConceptsDepressive symptomsAlcohol cravingAlcohol useEffects of vareniclineRole of nAChRsHuman laboratory studiesDSM-IV criteriaSymptoms of depressionAlcohol use disorderLaboratory testing sessionsMore depressive symptomsMedication pretreatmentPlasma levelsPriming doseVareniclineUse disordersTreatment moderatorsAlcohol consumptionDepression symptomsHeavy drinkersAlcohol usersDrinking taskSymptomsLess drinkingDrinkers
2016
Investigating Veterans’ Pre-, Peri-, and Post-Deployment Experiences as Potential Risk Factors for Problem Gambling
Whiting SW, Potenza MN, Park CL, McKee SA, Mazure CM, Hoff RA. Investigating Veterans’ Pre-, Peri-, and Post-Deployment Experiences as Potential Risk Factors for Problem Gambling. Journal Of Behavioral Addictions 2016, 5: 213-220. PMID: 27156377, PMCID: PMC5387772, DOI: 10.1556/2006.5.2016.027.Peer-Reviewed Original Research
2014
Crime and Psychiatric Disorders Among Youth in the US Population: An Analysis of the National Comorbidity Survey–Adolescent Supplement
Coker KL, Smith PH, Westphal A, Zonana HV, McKee SA. Crime and Psychiatric Disorders Among Youth in the US Population: An Analysis of the National Comorbidity Survey–Adolescent Supplement. Journal Of The American Academy Of Child & Adolescent Psychiatry 2014, 53: 888-898.e2. PMID: 25062596, PMCID: PMC4137504, DOI: 10.1016/j.jaac.2014.05.007.Peer-Reviewed Original ResearchConceptsNational Comorbidity Survey-Adolescent SupplementPsychiatric disordersPsychiatric comorbidityConduct disorderGreater oddsUS populationMental illnessDSM-IV-based diagnosisLifetime psychiatric disordersSpecific psychiatric disordersMental health servicesAlcohol use disorderRepresentative epidemiological sampleMore diagnosesUse disordersDrug useHealth servicesCommunity settingsLogistic regressionSimilar findingsDiagnosisEpidemiological sampleDisordersOddsSubstantial association
2013
The factor structure of the metabolic syndrome in obese individuals with binge eating disorder
Udo T, McKee SA, White MA, Masheb RM, Barnes RD, Grilo CM. The factor structure of the metabolic syndrome in obese individuals with binge eating disorder. Journal Of Psychosomatic Research 2013, 76: 152-157. PMID: 24439692, PMCID: PMC3953028, DOI: 10.1016/j.jpsychores.2013.10.007.Peer-Reviewed Original ResearchConceptsObese individualsMetabolic syndromeMetabolic measuresHigh-risk populationType II diabetesBlood pressurePatient groupExcess weightSubgroup analysisCardiovascular diseaseRisk populationsGlucose regulationTreatment studiesVARCLUS procedurePopulation studiesFactor structureSyndromeBingeDisordersMetSDiverse populationsFour-factor structureIndividualsStatistical Analysis SystemObesity
2012
How Can We Use Our Knowledge of Alcohol-Tobacco Interactions to Reduce Alcohol Use?
McKee SA, Weinberger AH. How Can We Use Our Knowledge of Alcohol-Tobacco Interactions to Reduce Alcohol Use? Annual Review Of Clinical Psychology 2012, 9: 649-674. PMID: 23157448, PMCID: PMC3651830, DOI: 10.1146/annurev-clinpsy-050212-185549.Peer-Reviewed Original ResearchDoes co-morbid depression alter the inverse relationship between obesity and substance use disorders?
Gearhardt AN, Harrison EL, McKee SA. Does co-morbid depression alter the inverse relationship between obesity and substance use disorders? Drug And Alcohol Dependence 2012, 124: 185-188. PMID: 22285319, PMCID: PMC3359394, DOI: 10.1016/j.drugalcdep.2012.01.002.Peer-Reviewed Original ResearchConceptsSubstance use disordersCo-morbid depressionDrug use disordersUse disordersRisk factorsMajor depressionOverweight/obesity statusCommon risk factorsInverse relationshipNormal weightObesity statusExcess food consumptionPsychiatric disordersDepression disorderObesityDrug useReward circuitryU.S. adultsSubstance useDisordersDepressionAdultsFood consumptionRepresentative sampleCurrent study
2008
Risk factors for treatment failure in smokers: Relationship to alcohol use and to lifetime history of an alcohol use disorder
Leeman RF, McKee SA, Toll BA, Krishnan-Sarin S, Cooney JL, Makuch RW, O'Malley SS. Risk factors for treatment failure in smokers: Relationship to alcohol use and to lifetime history of an alcohol use disorder. Nicotine & Tobacco Research 2008, 10: 1793-1809. PMID: 19023831, PMCID: PMC2764010, DOI: 10.1080/14622200802443742.Peer-Reviewed Original ResearchConceptsHeavy drinking daysAlcohol use disorderAUD historyCessation relapseUse disordersDrinking daysModerate drinkingAlcohol useSustained-release bupropionLifetime alcohol use disorderModerate alcohol usersRandomized clinical trialsAlcohol use categoriesProbability of smokingSmoking cessation failureTreatment failureAlcohol use levelsRisk factorsClinical trialsHazardous patternsTreatment periodHazardous drinkersAbstinent daysCessation failureAlcohol usersCorrespondence of Interactive Voice Response (IVR) Reports of Nicotine Withdrawal, Craving, and Negative Mood with Questionnaire Ratings
Toll BA, Cooney JL, McKee SA, O'Malley SS, Cooney NL. Correspondence of Interactive Voice Response (IVR) Reports of Nicotine Withdrawal, Craving, and Negative Mood with Questionnaire Ratings. Nicotine & Tobacco Research 2008, 10: 1057-1064. PMID: 18584469, PMCID: PMC2791461, DOI: 10.1080/14622200802097498.Peer-Reviewed Original ResearchConceptsNicotine withdrawalDepressive symptomsSmoking cessation trialCessation trialDaily smokersInteractive voice response systemVoice response systemDaily assessmentCravingWeeksNegative moodWithdrawalSymptomsPaper questionnaireQuestionnaire ratingsReportFuture studiesQuestionnaireIVR systemMoodDaysSample sizeDaily reportsSmokersSmokingCigarette Smoking and Intimate Partner Violence Among Men Referred to Substance Abuse Treatment
Easton CJ, Weinberger AH, McKee SA. Cigarette Smoking and Intimate Partner Violence Among Men Referred to Substance Abuse Treatment. The American Journal Of Drug And Alcohol Abuse 2008, 34: 39-46. PMID: 18161642, DOI: 10.1080/00952990701522682.Peer-Reviewed Original ResearchConceptsCigarette smokingSubstance abuse treatmentDaily smokersIntimate partner violenceAbuse treatmentNon-daily smokersCurrent cigarette smokingDaily cigarette smokingAlcohol dependent offendersAlcohol-dependent menAntisocial personality disorderPartner violenceASI alcoholDependent menSmokersSmokingAlcohol useDependent offendersMore daysPersonality disorderMore participantsTreatmentMenDaysParticipants
2007
Gender differences in the comorbidity of smoking behavior and major depression
Husky MM, Mazure CM, Paliwal P, McKee SA. Gender differences in the comorbidity of smoking behavior and major depression. Drug And Alcohol Dependence 2007, 93: 176-179. PMID: 17850991, PMCID: PMC2247435, DOI: 10.1016/j.drugalcdep.2007.07.015.Peer-Reviewed Original ResearchConceptsMajor depressionPrior smokingSmoking behaviorPast depressionDSM-IV major depressionPrior major depressionLifetime major depressionNational Epidemiologic SurveySmoking statusCessation interventionsDaily smokingOdds ratioHigh riskNicotine dependenceSmoking relapseEpidemiologic SurveySmokingLogistic regressionRelated conditionsDepressionWomenAssociationGender differencesFunction of genderComorbidities
2006
Reliability of the Fagerström Test for Nicotine Dependence, Minnesota Nicotine Withdrawal Scale, and Tiffany Questionnaire for Smoking Urges in Smokers with and without Schizophrenia
Weinberger AH, Reutenauer EL, Allen TM, Termine A, Vessicchio JC, Sacco KA, Easton CJ, McKee SA, George TP. Reliability of the Fagerström Test for Nicotine Dependence, Minnesota Nicotine Withdrawal Scale, and Tiffany Questionnaire for Smoking Urges in Smokers with and without Schizophrenia. Drug And Alcohol Dependence 2006, 86: 278-282. PMID: 16876968, DOI: 10.1016/j.drugalcdep.2006.06.005.Peer-Reviewed Original ResearchConceptsMinnesota Nicotine Withdrawal ScaleWithdrawal ScaleNicotine dependenceFagerström TestSmoking urgesDiagnostic groupsFactor 1Similar inclusion criteriaFactor 2Cotinine levelsInclusion criteriaSmoking measuresSmoking variablesSmokersCarbon monoxide levelsHigh carbon monoxide levelsNonpsychiatric smokersSchizophreniaTotal scoreTest-retest correlationsFTNDInternal consistencyFactor 1 scoresScoresQuestionnaire