2023
Testing the efficacy of real-time fMRI neurofeedback for training people who smoke daily to upregulate neural responses to nondrug rewards
Chung Y, White R, Geier C, Johnston S, Smyth J, Delgado M, McKee S, Wilson S. Testing the efficacy of real-time fMRI neurofeedback for training people who smoke daily to upregulate neural responses to nondrug rewards. Cognitive, Affective, & Behavioral Neuroscience 2023, 23: 440-456. PMID: 36788202, DOI: 10.3758/s13415-023-01070-y.Peer-Reviewed Original ResearchConceptsNondrug rewardsNeurofeedback trainingNeural responsesReal-time fMRI neurofeedback trainingReal-time fMRI neurofeedbackReward-related brain activityReward-related brain areasFMRI neurofeedback trainingTraining runsSingle neurofeedback sessionFMRI neurofeedbackBrain responsesNeurofeedback researchBrain activityBOLD activationNeurofeedback sessionsSuch rewardsStriatal activityNeurofeedbackControl conditionRewardBrain areasMonetary incentivesRecent researchSmoking cessation
2019
Use of Mentholated Cigarettes and Likelihood of Smoking Cessation in the United States: A Meta-Analysis
Smith PH, Assefa B, Kainth S, Salas-Ramirez KY, McKee SA, Giovino GA. Use of Mentholated Cigarettes and Likelihood of Smoking Cessation in the United States: A Meta-Analysis. Nicotine & Tobacco Research 2019, 22: 307-316. PMID: 31204787, PMCID: PMC7161928, DOI: 10.1093/ntr/ntz067.Peer-Reviewed Original ResearchConceptsAfrican American smokersSmoking cessationMenthol cigarette useAmerican smokersMenthol useUS smokersCigarette useComprehensive tobacco control effortCross-sectional studyNon-menthol usersPublic health benefitsTobacco control effortsEffect sizeBlack/African AmericanMentholated cigarettesMenthol banLower oddsSmokersMeta-AnalysisSignificant associationCessationLower likelihoodHealth benefitsQuantitative summaryStudy sampleSmoking Across the Menopausal Transition in a 10-Year Longitudinal Sample: The Role of Sex Hormones and Depressive Symptoms
Peltier MR, Flores JM, Smith PH, Roberts W, Verplaetse TL, Moore KE, Hacker R, Oberleitner LM, McKee SA. Smoking Across the Menopausal Transition in a 10-Year Longitudinal Sample: The Role of Sex Hormones and Depressive Symptoms. Nicotine & Tobacco Research 2019, 22: 872-877. PMID: 31058288, PMCID: PMC7249927, DOI: 10.1093/ntr/ntz069.Peer-Reviewed Original ResearchConceptsRegular smoking behaviorMenopausal transitionSmoking behaviorRegular smokingSex hormonesDepressive symptomsSmoking-related health consequencesMenopausal transition statusCigarette smoking ratesImpact of progesteroneRandom effects logistic regression modelHigher depression scoresMenopausal transition stageLogistic regression modelsContinued smokingSmoking cessationSmoking patternsSmoking ratesOlder womenDepression scoresSmokingWomen's healthSmoking transitionsHormone measuresHealth consequences
2018
Cigarette smoking among those with mental disorders in the US population: 2012–2013 update
Smith PH, Chhipa M, Bystrik J, Roy J, Goodwin RD, McKee SA. Cigarette smoking among those with mental disorders in the US population: 2012–2013 update. Tobacco Control 2018, 29: 29-35. PMID: 30377242, PMCID: PMC11533450, DOI: 10.1136/tobaccocontrol-2018-054268.Peer-Reviewed Original ResearchConceptsSubstance use disordersMental disordersCigarette smokingUse disordersCommon mental disordersPrevalence of lifetimePast-year smokingNational Epidemiologic SurveyRelated Conditions-IIICurrent cigarette useQuit ratioSmoking cessationSmoking prevalenceDaily smokingEpidemiologic SurveySmokingSpecific diagnosisPrevalence estimatesCigarette useUS populationTobacco controlPrevalenceCommon moodDisordersRepresentative estimatesIntersection of E-Cigarette Use and Gender on Transitions in Cigarette Smoking Status: Findings Across Waves 1 and 2 of the Population Assessment of Tobacco and Health Study
Verplaetse TL, Moore KE, Pittman BP, Roberts W, Oberleitner LM, Peltier M, Hacker R, Cosgrove KP, McKee SA. Intersection of E-Cigarette Use and Gender on Transitions in Cigarette Smoking Status: Findings Across Waves 1 and 2 of the Population Assessment of Tobacco and Health Study. Nicotine & Tobacco Research 2018, 21: 1423-1428. PMID: 30239953, PMCID: PMC6751514, DOI: 10.1093/ntr/nty187.Peer-Reviewed Original ResearchConceptsE-cigarette useE-cigarette usersCigarette smoking statusE-cigarettesSmoking statusSmoking cessationCigarette smokersSmoking relapseGreater riskDaily e-cigarette usersWave 1Stratified analysisHigher oddsHealth StudyPotential riskSmokingRelapseDrug AdministrationElectronic cigarettesSmokersPopulation AssessmentPotential aidMenWomenRisk
2017
The Effect of Treatment with Guanfacine, an Alpha2 Adrenergic Agonist, on Dopaminergic Tone in Tobacco Smokers: An [11C]FLB457 PET Study
Sandiego CM, Matuskey D, Lavery M, McGovern E, Huang Y, Nabulsi N, Ropchan J, Picciotto MR, Morris ED, McKee SA, Cosgrove KP. The Effect of Treatment with Guanfacine, an Alpha2 Adrenergic Agonist, on Dopaminergic Tone in Tobacco Smokers: An [11C]FLB457 PET Study. Neuropsychopharmacology 2017, 43: 1052-1058. PMID: 28944773, PMCID: PMC5854798, DOI: 10.1038/npp.2017.223.Peer-Reviewed Original ResearchConceptsTobacco smokersGuanfacine treatmentPositron emission tomographyTobacco smokingDA releaseDopaminergic toneDopamine releaseAmphetamine-induced DA releaseTobacco smoking cessationCortical dopamine releaseExtrastriatal brain regionsAlpha2-adrenergic agonistExtrastriatal dopamine releaseEffect of treatmentBaseline BPNDSmoking cessationReceptor radiotracerAdrenergic agonistsPET scansAnimal modelsBrain regionsEmission tomographyPET studiesDopamine signalingSmokersGender differences in the real-world effectiveness of smoking cessation medications: Findings from the 2010–2011 Tobacco Use Supplement to the Current Population Survey
Smith PH, Zhang J, Weinberger AH, Mazure CM, McKee SA. Gender differences in the real-world effectiveness of smoking cessation medications: Findings from the 2010–2011 Tobacco Use Supplement to the Current Population Survey. Drug And Alcohol Dependence 2017, 178: 485-491. PMID: 28715776, PMCID: PMC6779031, DOI: 10.1016/j.drugalcdep.2017.05.046.Peer-Reviewed Original ResearchConceptsTransdermal nicotine patchUnassisted quit attemptsClinical trial dataTobacco Use SupplementQuit attemptsTrial dataClinical trial findingsReal-world effectivenessSample of smokersGender differencesRelevant gender differencesCessation optionsCessation medicationsCessation pharmacotherapyNicotine patchMedication interactionsSmoking cessationPotential confoundersTrial findingsVareniclineComparative effectivenessPropensity scoreCross-sectional dataWomenMedicationsEffect of doxazosin on stress reactivity and the ability to resist smoking
Verplaetse TL, Weinberger AH, Oberleitner LM, Smith KM, Pittman BP, Shi JM, Tetrault JM, Lavery ME, Picciotto MR, McKee SA. Effect of doxazosin on stress reactivity and the ability to resist smoking. Journal Of Psychopharmacology 2017, 31: 830-840. PMID: 28440105, PMCID: PMC5823502, DOI: 10.1177/0269881117699603.Peer-Reviewed Original ResearchConceptsTobacco cravingCortisol levelsSubsequent ad libitum smokingEffects of doxazosinAd libitum smokingNumber of cigarettesNicotine-motivated behaviorsSmoking lapse behaviorΑ1-adrenergic antagonistNicotine-deprived smokersTitration periodPreclinical findingsSmoking cessationNoradrenergic systemTreatment strategiesDoxazosinSmoking behaviorSmokingHuman laboratoryPhysiologic reactivityPilot studyStress reactivityEffects of stressCigarettesStress imagery
2016
Sex/gender differences in smoking cessation: A review
Smith PH, Bessette AJ, Weinberger AH, Sheffer CE, McKee SA. Sex/gender differences in smoking cessation: A review. Preventive Medicine 2016, 92: 135-140. PMID: 27471021, PMCID: PMC5085924, DOI: 10.1016/j.ypmed.2016.07.013.Peer-Reviewed Original ResearchConceptsProspective observational studyObservational studyCross-sectional investigationSex/gender differencesSmoking cessationEffectiveness trialCommunity-based interventionsLong-term abstinenceGender differencesSmoker prevalenceEfficacy trialsOutcome assessmentTreatment studiesEpidemiological investigationsMeet criteriaStudy sampleTrialsCessationWomenRelapseSmokingBio-psychoMenQualitative reviewReviewSex Differences in Smoking Cessation Pharmacotherapy Comparative Efficacy: A Network Meta-analysis
Smith PH, Weinberger AH, Zhang J, Emme E, Mazure CM, McKee SA. Sex Differences in Smoking Cessation Pharmacotherapy Comparative Efficacy: A Network Meta-analysis. Nicotine & Tobacco Research 2016, 19: 273-281. PMID: 27613893, PMCID: PMC5939704, DOI: 10.1093/ntr/ntw144.Peer-Reviewed Original ResearchConceptsTransdermal nicotineSmoking cessationBupropion SRComparative efficacyFirst option treatmentSustained release bupropionPlacebo-controlled trialSex differencesCigarette smoking cessationNetwork Meta-AnalysisRelease bupropionCessation pharmacotherapyOption treatmentGeneral community sampleCigarette smokersQuit ratesVarenicline's efficacyPharmacological interventionsVareniclineBupropionNicotine addictionMeta-AnalysisPlaceboSimilar outcomesSignificant sex differences
2015
Childhood adversity, stress-sensitization, and lower likelihood of cigarette smoking cessation in a U.S. nationally representative sample: A study of sex differences
Smith P, Oberleitner L, Smith K, Mckee S. Childhood adversity, stress-sensitization, and lower likelihood of cigarette smoking cessation in a U.S. nationally representative sample: A study of sex differences. Drug And Alcohol Dependence 2015, 156: e207. DOI: 10.1016/j.drugalcdep.2015.07.557.Peer-Reviewed Original ResearchSex Differences in Varenicline Efficacy for Smoking Cessation: A Meta-Analysis
McKee SA, Smith PH, Kaufman M, Mazure CM, Weinberger AH. Sex Differences in Varenicline Efficacy for Smoking Cessation: A Meta-Analysis. Nicotine & Tobacco Research 2015, 18: 1002-1011. PMID: 26446070, PMCID: PMC5942618, DOI: 10.1093/ntr/ntv207.Peer-Reviewed Original ResearchConceptsSmoking cessation medicationsCessation medicationsSmoking cessationDouble-blind placebo-controlled trialEfficacy of vareniclinePlacebo-controlled trialShort-term outcomesClinical trial dataSex differencesSimilar ratesWeek 52Week 24Women smokersNicotine replacementWeek 12Outcome endpointsTherapeutic responseClinical trialsContinuous abstinenceVarenicline's efficacyVareniclinePlacebo outcomesEqual efficacySex disparitiesEffective FDAChildhood Adversity Interacts With Adult Stressful Events to Predict Reduced Likelihood of Smoking Cessation Among Women but Not Men
Smith PH, Oberleitner LM, Smith KM, McKee SA. Childhood Adversity Interacts With Adult Stressful Events to Predict Reduced Likelihood of Smoking Cessation Among Women but Not Men. Clinical Psychological Science 2015, 4: 183-193. PMID: 27026829, PMCID: PMC4808300, DOI: 10.1177/2167702615584589.Peer-Reviewed Original ResearchSmoking cessationStressful life eventsChildhood adversityNon-daily smokersNational Epidemiologic SurveySex differencesLife eventsImportant sex differencesStress sensitization modelPsychiatric outcomesEpidemiologic SurveyClinical targetsRelated conditionsThree-way interactionCessationLower likelihoodEarly stressWomenStressful eventsWave 1MenCurrent studyFurther explorationAdversitySmokersInfluence of the A118G Polymorphism of the OPRM1 Gene and Exon 3 VNTR Polymorphism of the DRD4 Gene on Cigarette Craving After Alcohol Administration
Lechner WV, Knopik VS, McGeary JE, Spillane NS, Tidey JW, McKee SA, Metrik J, Leventhal AM, Rohsenow DJ, Kahler CW. Influence of the A118G Polymorphism of the OPRM1 Gene and Exon 3 VNTR Polymorphism of the DRD4 Gene on Cigarette Craving After Alcohol Administration. Nicotine & Tobacco Research 2015, 18: 632-636. PMID: 26092968, PMCID: PMC5896808, DOI: 10.1093/ntr/ntv136.Peer-Reviewed Original ResearchConceptsA118G polymorphismG polymorphismOPRM1 geneAlcohol administrationG carriersG alleleRepeated-measures design studyA118G genotypeG allele carriersDose of alcoholVNTR polymorphismMean age 39.2Greater increaseSmoking cessationAge 39.2Allele carriersCigarette cravingG genotypeHigh doseAlcohol consumptionHeavy drinkersThree-sessionDRD4 geneHeavy drinkingVNTR genotypeThe Relationship Between Childhood Physical and Emotional Abuse and Smoking Cessation Among U.S. Women and Men
Smith PH, Saddleson ML, Homish GG, McKee SA, Kozlowski LT, Giovino GA. The Relationship Between Childhood Physical and Emotional Abuse and Smoking Cessation Among U.S. Women and Men. Psychology Of Addictive Behaviors 2015, 29: 338-346. PMID: 25347015, PMCID: PMC4486346, DOI: 10.1037/adb0000033.Peer-Reviewed Original ResearchConceptsSerious psychological distressChildhood maltreatmentQuit attemptsActual quit attemptsCurrent cigarette smokersSuccessful quit attemptsU.S. adult smokersNational U.S. sampleLikelihood of smokingFemale smokersPsychological distressSmoking cessationCigarette smokersAdult smokersSmoking outcomesSmokingMore difficultyMaltreatmentSmokersU.S. sampleLower likelihoodTelephone surveyPath modelingMotivationWomenA Randomized Trial for Hazardous Drinking and Smoking Cessation for Callers to a Quitline
Toll BA, Martino S, O’Malley S, Fucito LM, McKee SA, Kahler CW, Rojewski AM, Mahoney MC, Wu R, Celestino P, Seshadri S, Koutsky J, Hyland A, Cummings KM. A Randomized Trial for Hazardous Drinking and Smoking Cessation for Callers to a Quitline. Journal Of Consulting And Clinical Psychology 2015, 83: 445-454. PMID: 25419583, PMCID: PMC5996380, DOI: 10.1037/a0038183.Peer-Reviewed Original ResearchConceptsStandard careHazardous drinkingHigher smoking cessation ratesNew York State Smokers' QuitlineHeavy drinkingBrief motivational counselingSmoking cessation ratesState Smokers' QuitlineBrief alcohol interventionTelephone coachesCessation counselingTreat analysisCessation ratesRandomized trialsTelephone quitlinesCessation successSmoking cessationAcceptable adherenceMotivational counselingQuitlineAlcohol interventionsAlcohol useCareSmokersDrinkingGender Differences in Medication Use and Cigarette Smoking Cessation: Results From the International Tobacco Control Four Country Survey
Smith PH, Kasza KA, Hyland A, Fong GT, Borland R, Brady K, Carpenter MJ, Hartwell K, Cummings KM, McKee SA. Gender Differences in Medication Use and Cigarette Smoking Cessation: Results From the International Tobacco Control Four Country Survey. Nicotine & Tobacco Research 2015, 17: 463-472. PMID: 25762757, PMCID: PMC4402353, DOI: 10.1093/ntr/ntu212.Peer-Reviewed Original ResearchConceptsMedication useInternational Tobacco Control Four Country SurveySmoking cessationFour Country SurveyQuit attemptsCessation medication useCigarette smoking cessationGender differencesAdjusted modelingQuit attemptersNicotine patchSuccessful quittingSubsample of smokersAdult smokersLower oddsCountry SurveyWomenSelf-selected useCessationSmokersSCM useMenWaves 2006Survey wavesVareniclineTargeting the Noradrenergic System for Gender-Sensitive Medication Development for Tobacco Dependence
Verplaetse TL, Weinberger AH, Smith PH, Cosgrove KP, Mineur YS, Picciotto MR, Mazure CM, McKee SA. Targeting the Noradrenergic System for Gender-Sensitive Medication Development for Tobacco Dependence. Nicotine & Tobacco Research 2015, 17: 486-495. PMID: 25762760, PMCID: PMC4432402, DOI: 10.1093/ntr/ntu280.Peer-Reviewed Original ResearchConceptsSmoking cessationNoradrenergic systemClinical evidenceTobacco dependenceNoradrenergic activityMedication developmentPoor smoking cessation outcomesCause of morbiditySmoking cessation outcomesStress reactivitySex-specific mechanismsLower quit ratesNicotine-related reinforcementCurrent medicationsMedication effectivenessNicotine reinforcementCessation outcomesNoradrenergic agentsQuit ratesTreatment strategiesTobacco useNoradrenergic compoundsSmoking outcomesTreatment developmentWomen
2014
Consideration of Sex in Clinical Trials of Transdermal Nicotine Patch: A Systematic Review
Weinberger AH, Smith PH, Kaufman M, McKee SA. Consideration of Sex in Clinical Trials of Transdermal Nicotine Patch: A Systematic Review. Experimental And Clinical Psychopharmacology 2014, 22: 373-383. PMID: 25133506, PMCID: PMC4180800, DOI: 10.1037/a0037692.Peer-Reviewed Original ResearchConceptsTransdermal nicotine patchNicotine patchCessation outcomesClinical trialsSmoking cessationSmoking cessation treatmentMenstrual cycle phaseCessation treatmentSex-related variablesInclusion criteriaMEDLINE searchSmoking treatmentSide effectsBetter outcomesTreatment efficacyConsideration of sexSystematic reviewPotential articlesInclusion of sexSkin irritationMore womenTrialsOutcomesSexWomenStability of smoking status in the US population: a longitudinal investigation
Weinberger AH, Pilver CE, Mazure CM, McKee SA. Stability of smoking status in the US population: a longitudinal investigation. Addiction 2014, 109: 1541-1553. PMID: 24916157, PMCID: PMC4127136, DOI: 10.1111/add.12647.Peer-Reviewed Original ResearchConceptsCurrent daily smokersDaily smokersSmoking statusSmoking cessationSmoking transitionsGeneral US adult populationNon-daily smokersFormer daily smokersUS adult populationNational Epidemiologic SurveyWave 1Daily smokingUS adultsSmokersEpidemiologic SurveyHispanic adultsUS populationAdult populationRelated conditionsOlder adultsLess educationAdultsLongitudinal studySmokingIntervention efforts