2022
Modeling ability to resist alcohol in the human laboratory: A pilot study
Sloan M, Sells J, Vaughan C, Morris J, Ortega N, Sundar S, Soundararajan S, Stangl B, Gowin J, Chawla S, Diazgranados N, McKee S, Waters A, Ramchandani V. Modeling ability to resist alcohol in the human laboratory: A pilot study. Drug And Alcohol Dependence Reports 2022, 5: 100105. PMID: 36844167, PMCID: PMC9948911, DOI: 10.1016/j.dadr.2022.100105.Peer-Reviewed Original ResearchAlcohol self-administration paradigmSelf-administration paradigmCox proportional hazards regressionAlcohol usePilot studyLow-risk consumptionRisk of lapseHalf of patientsProportional hazards regressionSelf-administer alcoholAlcohol use disorderAlcohol intakeHazards regressionPriming doseUse disordersScale scoreHeavy drinkersHuman laboratoryImpaired controlInitial exposureCharacteristics of individualsPreliminary evidenceControl Scale scoresFuture studiesIndividuals
2017
Effect of doxazosin on stress reactivity and the ability to resist smoking
Verplaetse TL, Weinberger AH, Oberleitner LM, Smith KM, Pittman BP, Shi JM, Tetrault JM, Lavery ME, Picciotto MR, McKee SA. Effect of doxazosin on stress reactivity and the ability to resist smoking. Journal Of Psychopharmacology 2017, 31: 830-840. PMID: 28440105, PMCID: PMC5823502, DOI: 10.1177/0269881117699603.Peer-Reviewed Original ResearchConceptsTobacco cravingCortisol levelsSubsequent ad libitum smokingEffects of doxazosinAd libitum smokingNumber of cigarettesNicotine-motivated behaviorsSmoking lapse behaviorΑ1-adrenergic antagonistNicotine-deprived smokersTitration periodPreclinical findingsSmoking cessationNoradrenergic systemTreatment strategiesDoxazosinSmoking behaviorSmokingHuman laboratoryPhysiologic reactivityPilot studyStress reactivityEffects of stressCigarettesStress imagery
2014
Heightened vagal activity during high-calorie food presentation in obese compared with non-obese individuals—Results of a pilot study
Udo T, Weinberger AH, Grilo CM, Brownell KD, DiLeone RJ, Lampert R, Matlin SL, Yanagisawa K, McKee SA. Heightened vagal activity during high-calorie food presentation in obese compared with non-obese individuals—Results of a pilot study. Obesity Research & Clinical Practice 2014, 8: e258-e265. PMID: 24847667, PMCID: PMC4031442, DOI: 10.1016/j.orcp.2013.05.006.Peer-Reviewed Original ResearchConceptsNon-obese individualsHigh-calorie food itemsVagal activityObese individualsHF-HRVHigh-frequency heart rate variabilityHeart rate variabilityConsumption of foodPalatable foodFood itemsAppetitive behaviorCue reactivityPilot studyFood presentationRate variabilityFood cuesFood deprivationObesePotential roleMood statesHRVFurther investigationPresentationInductionMood induction
2013
A preliminary study on the effect of combined nicotine replacement therapy on alcohol responses and alcohol self‐administration
Udo T, Harrison EL, Shi J, Tetrault J, McKee SA. A preliminary study on the effect of combined nicotine replacement therapy on alcohol responses and alcohol self‐administration. American Journal On Addictions 2013, 22: 590-597. PMID: 24131167, PMCID: PMC3934424, DOI: 10.1111/j.1521-0391.2013.12014.x.Peer-Reviewed Original ResearchConceptsSelf-administration periodNicotine nasal sprayHeavy drinking smokersNasal sprayNicotine patchAlcohol responsesPriming drinkSerum nicotine levelsPlacebo-controlled studyNicotine replacement therapySubjective alcohol responsesPositive subjective responsesNumber of drinksPlacebo administrationReplacement therapyPriming doseSmoking relapseAlcohol consumptionPlacebo conditionPatch applicationNicotine levelsClinical settingPilot studySmokersSubjective responses
2012
Smoking Cue Reactivity in Adult Smokers with and without Depression: A Pilot Study
Weinberger AH, McKee SA, George TP. Smoking Cue Reactivity in Adult Smokers with and without Depression: A Pilot Study. American Journal On Addictions 2012, 21: 136-144. PMID: 22332857, PMCID: PMC3647350, DOI: 10.1111/j.1521-0391.2011.00203.x.Peer-Reviewed Original ResearchConceptsMajor depressive disorderDiagnosis of MDDCue-induced urgesCue reactivityAdult smokersSmoking cuesPast major depressive disorderMDD historyPilot studySmoking cue reactivitySmoking-related behaviorsCurrent depressive symptomsCue-induced cravingPreferred brand cigarettesDepressive disorderDiagnosis groupsSmoking variablesDepressive symptomsCurrent symptomsSmoking behaviorSmoking urgesDepression symptomsSmokersSymptomsUseful procedure
2006
Contingency Management for Smoking Cessation in Adolescent Smokers
Krishnan-Sarin S, Duhig AM, McKee SA, McMahon TJ, Liss T, McFetridge A, Cavallo DA. Contingency Management for Smoking Cessation in Adolescent Smokers. Experimental And Clinical Psychopharmacology 2006, 14: 306-310. PMID: 16893273, DOI: 10.1037/1064-1297.14.3.306.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyAdolescent smokersSchool-based smoking cessation programUrine cotinine levelsMonths of treatmentWeekly cognitive behavioral therapySmoking cessation programCBT alone groupCotinine levelsCessation programsContingency management proceduresBiochemical verificationPilot studyDaily appointmentsWeeksContingency managementAbstinenceCessationSmokersAdolescentsGroupReset contingencyParticipantsTherapyMonths