2017
Effects of varenicline on alcohol self-administration and craving in drinkers with depressive symptoms
Roberts W, Verplaetse TL, Moore K, Oberleitner L, Picciotto MR, McKee SA. Effects of varenicline on alcohol self-administration and craving in drinkers with depressive symptoms. Journal Of Psychopharmacology 2017, 31: 906-914. PMID: 28351203, PMCID: PMC5823265, DOI: 10.1177/0269881117699618.Peer-Reviewed Original ResearchConceptsDepressive symptomsAlcohol cravingAlcohol useEffects of vareniclineRole of nAChRsHuman laboratory studiesDSM-IV criteriaSymptoms of depressionAlcohol use disorderLaboratory testing sessionsMore depressive symptomsMedication pretreatmentPlasma levelsPriming doseVareniclineUse disordersTreatment moderatorsAlcohol consumptionDepression symptomsHeavy drinkersAlcohol usersDrinking taskSymptomsLess drinkingDrinkers
2008
Risk factors for treatment failure in smokers: Relationship to alcohol use and to lifetime history of an alcohol use disorder
Leeman RF, McKee SA, Toll BA, Krishnan-Sarin S, Cooney JL, Makuch RW, O'Malley SS. Risk factors for treatment failure in smokers: Relationship to alcohol use and to lifetime history of an alcohol use disorder. Nicotine & Tobacco Research 2008, 10: 1793-1809. PMID: 19023831, PMCID: PMC2764010, DOI: 10.1080/14622200802443742.Peer-Reviewed Original ResearchConceptsHeavy drinking daysAlcohol use disorderAUD historyCessation relapseUse disordersDrinking daysModerate drinkingAlcohol useSustained-release bupropionLifetime alcohol use disorderModerate alcohol usersRandomized clinical trialsAlcohol use categoriesProbability of smokingSmoking cessation failureTreatment failureAlcohol use levelsRisk factorsClinical trialsHazardous patternsTreatment periodHazardous drinkersAbstinent daysCessation failureAlcohol users