2013
Ventromedial prefrontal cortex and the regulation of physiological arousal
Zhang S, Hu S, Chao HH, Ide JS, Luo X, Farr OM, Li CS. Ventromedial prefrontal cortex and the regulation of physiological arousal. Social Cognitive And Affective Neuroscience 2013, 9: 900-908. PMID: 23620600, PMCID: PMC4090954, DOI: 10.1093/scan/nst064.Peer-Reviewed Original ResearchConceptsSkin conductance levelVentromedial prefrontal cortexPrefrontal cortexDorsal anterior cingulate cortexCausal roleAnterior cingulate cortexFunctional magnetic resonance imagingMagnetic resonance imagingCerebral blood oxygenationSkin conductance measurementsHealthy adultsPhysiological arousalUnderstanding of dysfunctionCingulate cortexResonance imagingBrain regionsBlood oxygenationAnxiety disordersAltered controlCortexGranger causality analysisSkin conductance responsesBehavioral tasksPhasic skin conductance responsesSkin conductance
2012
Neural Processes of an Indirect Analog of Risk Taking in Young Nondependent Adult Alcohol Drinkers—An fMRI Study of the Stop Signal Task
Bednarski SR, Erdman E, Luo X, Zhang S, Hu S, Li C. Neural Processes of an Indirect Analog of Risk Taking in Young Nondependent Adult Alcohol Drinkers—An fMRI Study of the Stop Signal Task. Alcohol Clinical And Experimental Research 2012, 36: 768-779. PMID: 22339607, PMCID: PMC3647608, DOI: 10.1111/j.1530-0277.2011.01672.x.Peer-Reviewed Original ResearchConceptsStop-signal taskAlcohol useNeural processesSignal taskSocial drinkingRisk takingYoung adult social drinkersFrequency of drinkingAdult social drinkersRight superior frontal gyrusFunctional magnetic resonanceSelf-reported alcohol useSuperior frontal gyrusBrain imaging dataSuperior frontal cortexDangerous alcohol consumptionCognitive factorsNeural correlatesFMRI studyFrontal gyrusSocial drinkersHigh-level drinkingCorresponding effect sizesNumber of drinksNondependent drinkers
2011
Deficits in default mode network activity preceding error in cocaine dependent individuals
Bednarski SR, Zhang S, Hong KI, Sinha R, Rounsaville BJ, Li CS. Deficits in default mode network activity preceding error in cocaine dependent individuals. Drug And Alcohol Dependence 2011, 119: e51-e57. PMID: 21703783, PMCID: PMC3188675, DOI: 10.1016/j.drugalcdep.2011.05.026.Peer-Reviewed Original ResearchConceptsDefault mode networkCocaine dependenceCocaine useHealthy controlsTask-related cerebral activationBlood oxygenation level-dependent (BOLD) signalDemographics-matched healthy controlsGray matter volumeDefault mode network activityLevel-dependent signalChronic cocaine useRegional brain activationPosterior cingulate cortexStatistical parametric mappingCerebral functionBilateral precuneusCocaine-dependent individualsCerebral activationHealthy peopleMatter volumeCingulate cortexVentromedial prefrontal cortexBrain regionsCognitive deficitsCocaine misuseFunctional networks for cognitive control in a stop signal task: Independent component analysis
Zhang S, Li C. Functional networks for cognitive control in a stop signal task: Independent component analysis. Human Brain Mapping 2011, 33: 89-104. PMID: 21365716, PMCID: PMC3674850, DOI: 10.1002/hbm.21197.Peer-Reviewed Original ResearchConceptsStop-signal taskCognitive controlFronto-parietal networkStop successError processingSignal taskComponent processesFunctional networksLeft fronto-parietal networkRight fronto-parietal networkSelf-referential processingCritical executive functionCortico-subcortical networksAttentional monitoringExecutive functionResponse inhibitionError trialsNeural processesIndependent component analysisBehavioral engagementMotor preparationMotor cortical networkCortical networksSE trialsLinear modeling
2009
A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus
Zhang S, Li CS. A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus. NeuroImage 2009, 49: 1911-1918. PMID: 19761851, PMCID: PMC2791356, DOI: 10.1016/j.neuroimage.2009.09.004.Peer-Reviewed Original ResearchConceptsBlood oxygenation level-dependent activityRegional brain activationLevel-dependent activityTask engagementNeural measuresNeural processesBrain activationPosterior cingulate cortexAttentional monitoringResponse inhibitionHuman cognitionPrefrontal activationSignal taskGreater activationBOLD activityBehavioral engagementCingulate cortexPrecuneusBrain regionsLow-frequency fluctuationsFractional amplitudeBrain imagingSeed regionIndependent component analysisEngagement
2008
Error-specific medial cortical and subcortical activity during the stop signal task: A functional magnetic resonance imaging study
Li C, Yan P, Chao H, Sinha R, Paliwal P, Constable RT, Zhang S, Lee T. Error-specific medial cortical and subcortical activity during the stop signal task: A functional magnetic resonance imaging study. Neuroscience 2008, 155: 1142-1151. PMID: 18674592, PMCID: PMC2605269, DOI: 10.1016/j.neuroscience.2008.06.062.Peer-Reviewed Original ResearchConceptsPost-error behavioral adjustmentPost-error slowingBehavioral adjustmentSignal taskFunctional magnetic resonance imaging studyConflict monitoring hypothesisError-related activityFunctional magnetic resonance imagingHigh-conflict trialsTrial reaction timeStop-signal taskMedial cortical regionsCortical brain regionsMagnetic resonance imaging studyResonance imaging studyElicit errorsBrain activationLess activationSubcortical activityCortical activityRetrosplenial cortexMonitoring hypothesisBehavioral outputBrain regionsCortical regions