Age-related reduction in anxiety and neural encoding of negative emotional memory
Chaudhary S, Zhang S, Chen Y, Dominguez J, Chao H, Li C. Age-related reduction in anxiety and neural encoding of negative emotional memory. Frontiers In Aging Neuroscience 2024, 16: 1375435. PMID: 39021704, PMCID: PMC11252031, DOI: 10.3389/fnagi.2024.1375435.Peer-Reviewed Original ResearchNegative emotional memoriesSpielberger State-Trait Anxiety InventoryEmotional memoryAge-related reductionSpielberger State-Trait Anxiety Inventory scoresWhole-brain regressionNegative emotional imagesState-Trait Anxiety InventoryTrait Anxiety InventoryAge-related differencesSignal detection theoryMemory taskNeutral imagesAge-related changesEmotional imagesAnxiety InventoryMediation analysisAnxietyPost-scanCortical activityNeural encodingState scoresMemoryOlder adultsDetection theorySex differences in the effects of individual anxiety state on regional responses to negative emotional scenes
Chaudhary S, Wong H, Chen Y, Zhang S, Li C. Sex differences in the effects of individual anxiety state on regional responses to negative emotional scenes. Biology Of Sex Differences 2024, 15: 15. PMID: 38351045, PMCID: PMC10863151, DOI: 10.1186/s13293-024-00591-6.Peer-Reviewed Original ResearchConceptsMedial prefrontal cortexState-Trait Anxiety InventoryFunctional magnetic resonance imagingState-Trait Anxiety Inventory scoresSuperior frontal gyrusGeneralized psychophysiological interactionEmotional processingFrontal gyrusLingual gyrusMedial prefrontal cortex connectivityMedial prefrontal cortex activationSex differencesRight inferior frontal gyrusResponse to negative emotionsRight superior frontal gyrusFunctional magnetic resonance imaging dataReaction timeImpact emotional processingNegative emotion processingInferior frontal gyrusLeft parahippocampal gyrusNegative emotional scenesMarkers of anxietyRepeated-measures analysis of covarianceLevels of anxiety