2022
Hypothalamic Functional Connectivity and Apathy in People with Alzheimer’s Disease and Cognitively Normal Healthy Controls
Chaudhary S, Zhornitsky S, Chao H, van Dyck C, Li C. Hypothalamic Functional Connectivity and Apathy in People with Alzheimer’s Disease and Cognitively Normal Healthy Controls. Journal Of Alzheimer's Disease 2022, 90: 1615-1628. PMID: 36314209, PMCID: PMC10064487, DOI: 10.3233/jad-220708.Peer-Reviewed Original ResearchConceptsMiddle temporal gyrusMild cognitive impairmentMotivation circuitsFunctional connectivityPath analysisWhole-brain regressionPCu/PCCState functional connectivityTotal scoreTemporal gyrusNeural markersCingulate cortexMemory dysfunctionRSFCHealthy controlsCognitive statusCognitive impairmentAlzheimer's diseaseApathyPrecuneusMemoryRsFCsDepressionScale total scoreCognitive subscoresCerebral Volumetric Correlates of Apathy in Alzheimer’s Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort
Chaudhary S, Zhornitsky S, Chao HH, van Dyck CH, Li CR. Cerebral Volumetric Correlates of Apathy in Alzheimer’s Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort. Journal Of Alzheimer's Disease 2022, 85: 1251-1265. PMID: 34924392, PMCID: PMC9215906, DOI: 10.3233/jad-215316.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseInferior frontal gyrusIndependent cohortEmotional scoresHealthy controlsCognitive impairmentVolumetric correlatesMini-Mental State Examination scoreAD/mild cognitive impairmentNeuroanatomical correlatesState Examination scoreApathy Evaluation ScaleGray matter volumeVoxel-based morphometryRight inferior frontal gyrusLabel-based reviewMild cognitive impairmentNormal older adultsCortical atrophyHigh morbidityBasal gangliaRight putamenMatter volumeAnterior cingulateReduced quality
2020
Domain specific cognitive impairment in Parkinson’s patients with mild cognitive impairment
Chaudhary S, Kumaran S, Kaloiya G, Goyal V, Sagar R, Kalaivani M, Jaganathan N, Mehta N, Srivastava A. Domain specific cognitive impairment in Parkinson’s patients with mild cognitive impairment. Journal Of Clinical Neuroscience 2020, 75: 99-105. PMID: 32192853, DOI: 10.1016/j.jocn.2020.03.015.Peer-Reviewed Original ResearchConceptsMild cognitive impairmentCognitive impairmentVisuospatial functionCognitive domain specificitySpecific cognitive impairmentsCognitive Assessment testMontreal Cognitive Assessment (MoCA) testStage of MCIExecutive functionPD clinical scoresDigit spanPD-MCIPD cognitionFronto-striatalRecall domainsDomain specificityCognitive AssessmentPD groupPotential confoundsCognitionCognitive pathophysiologyCortical syndromesCategorization of subjectsMemoryNormal cognition