2024
Gray Matter Atrophy in a 6-OHDA-induced Model of Parkinson’s Disease
Kumari S, Rana B, Kumaran S, Chaudhary S, Jain S, Srivastava A, Rajan R. Gray Matter Atrophy in a 6-OHDA-induced Model of Parkinson’s Disease. Neuroscience 2024, 551: 217-228. PMID: 38843989, DOI: 10.1016/j.neuroscience.2024.05.029.Peer-Reviewed Original ResearchVolume-based morphometryGray matter volumeMachine learningMagnetic resonance imagingClassification accuracyGray matter atrophySham controlsSupport vector machine (SVM)-based algorithmContralateral rotational behaviorUnilateral 6-hydroxydopamineIncrease classification accuracyAssociated with progressionMatter volumeModel of Parkinson's diseaseParkinson's diseaseBrain regionsBasal ganglia-thalamocortical circuitsPD modelSubcortical brain regionsGMV changesGray matter volume atrophyBrain morphometric changesInternal capsuleStudy of alterationsSubstantia nigra
2022
Overnight Abstinence Is Associated With Smaller Secondary Somatosensory Cortical Volumes and Higher Somatosensory-Motor Cortical Functional Connectivity in Cigarette Smokers
Chen Y, Dhingra I, Chaudhary S, Fucito L, Li CR. Overnight Abstinence Is Associated With Smaller Secondary Somatosensory Cortical Volumes and Higher Somatosensory-Motor Cortical Functional Connectivity in Cigarette Smokers. Nicotine & Tobacco Research 2022, 24: 1889-1897. PMID: 35796689, PMCID: PMC9653081, DOI: 10.1093/ntr/ntac168.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityGray matter volumeWithdrawal symptom severityOvernight abstinenceFunctional connectivityRight SIISymptom severityCigarette smokersSomatosensory cortexMatter volumeRight secondary somatosensory cortexSmaller gray matter volumeSubcortical gray matter volumesSecond somatosensory cortexSecondary somatosensory cortexCortical functional connectivityMotor impulsivityVoxel-wise morphometryRegional gray matter volumeLeft ventral hippocampusGMV alterationsCigarette smokingSatiety stateAbstinence symptomsHigher-order sensory corticesGray matter volumetric correlates of dimensional impulsivity traits in children: Sex differences and heritability
Chen Y, Ide JS, Li CS, Chaudhary S, Le TM, Wang W, Zhornitsky S, Zhang S, Li C. Gray matter volumetric correlates of dimensional impulsivity traits in children: Sex differences and heritability. Human Brain Mapping 2022, 43: 2634-2652. PMID: 35212098, PMCID: PMC9057091, DOI: 10.1002/hbm.25810.Peer-Reviewed Original ResearchConceptsGray matter volumeImpulsivity traitsPositive urgencyVolumetric correlatesSensation seekingHigher positive urgencyMid-cingulate cortexSex differencesVoxel-based morphometry analysisSmaller gray matter volumeImpulsivity dimensionsSubsample of twinsDistinct correlatesCingulate cortexPrecentral gyrusSubcortical gray matter volumesMatter volumeTotal intracranial volumeSeekingImpulsivityMorphometry analysisPrevious researchInsulaCorrelatesGirlsCerebral Volumetric Correlates of Apathy in Alzheimer’s Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort
Chaudhary S, Zhornitsky S, Chao HH, van Dyck CH, Li CR. Cerebral Volumetric Correlates of Apathy in Alzheimer’s Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort. Journal Of Alzheimer's Disease 2022, 85: 1251-1265. PMID: 34924392, PMCID: PMC9215906, DOI: 10.3233/jad-215316.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseInferior frontal gyrusIndependent cohortEmotional scoresHealthy controlsCognitive impairmentVolumetric correlatesMini-Mental State Examination scoreAD/mild cognitive impairmentNeuroanatomical correlatesState Examination scoreApathy Evaluation ScaleGray matter volumeVoxel-based morphometryRight inferior frontal gyrusLabel-based reviewMild cognitive impairmentNormal older adultsCortical atrophyHigh morbidityBasal gangliaRight putamenMatter volumeAnterior cingulateReduced quality
2021
Gray matter volumes of the insula and anterior cingulate cortex and their dysfunctional roles in cigarette smoking
Chen Y, Chaudhary S, Wang W, Li C. Gray matter volumes of the insula and anterior cingulate cortex and their dysfunctional roles in cigarette smoking. Addiction Neuroscience 2021, 1: 100003. PMID: 37220533, PMCID: PMC10201991, DOI: 10.1016/j.addicn.2021.100003.Peer-Reviewed Original ResearchGray matter volumeAnterior cingulate cortexYears of smokingHeavy smokersMatter volumeCingulate cortexSalience networkSmaller gray matter volumeSupplementary motor areaNicotine dependence scoresDorsal anterior cingulate cortexVoxel-based morphometryStructural imaging studiesMedial prefrontal cortexInternalizing scoresChronic smokingCigarette smokingFagerstrom TestInsula gray matter volumeMotor areaNicotine addictionSmokersSmokingImaging studiesDependence scoresPerceived stress, self-efficacy, and the cerebral morphometric markers in binge-drinking young adults
Li G, Le TM, Wang W, Zhornitsky S, Chen Y, Chaudhary S, Zhu T, Zhang S, Bi J, Tang X, Li CR. Perceived stress, self-efficacy, and the cerebral morphometric markers in binge-drinking young adults. NeuroImage Clinical 2021, 32: 102866. PMID: 34749288, PMCID: PMC8569726, DOI: 10.1016/j.nicl.2021.102866.Peer-Reviewed Original ResearchConceptsGray matter volumePerceived stressNeural markersRegional cortical thicknessCortical structuresAlcohol use behaviorsNon-binge drinkersHuman Connectome ProjectChronic alcohol exposure altersCortical thicknessVoxel-based morphometryEmotional distressConnectome ProjectDrinking menPath analysisCortical regionsDrinking womenBinge drinkingMatter volumeYoung adultsUse behaviorsStress regulationPCC thicknessBingeAlcohol exposure alters