2022
In vitro and in vivo NMR based metabolomics in Parkinson's disease
Chaudhary S, Kumari S, Kumaran S, Goyal V, Jain S, Kaloiya G. In vitro and in vivo NMR based metabolomics in Parkinson's disease. Journal Of Magnetic Resonance Open 2022, 10: 100050. DOI: 10.1016/j.jmro.2022.100050.Peer-Reviewed Original ResearchNon-motor symptomsParkinson's diseaseMetabolic alterationsCognitive impairmentCommon non-motor symptomCerebral metabolic alterationsPathophysiological progressionPD subgroupsEarly diagnosisEarly changesDisease pathophysiologyBrain metabolitesSpecific biomarkersNeurodegenerative diseasesDiseaseMagnetic resonance spectroscopy techniquesSymptomsImpairmentAlterationsNon-invasive characterizationPathophysiologyDementiaDiagnosisProgressionBiomarkers
2020
Cortical thickness and gyrification index measuring cognition in Parkinson’s disease
Chaudhary S, Kumaran S, Goyal V, Kaloiya G, Kalaivani M, Jagannathan N, Sagar R, Mehta N, Srivastava A. Cortical thickness and gyrification index measuring cognition in Parkinson’s disease. International Journal Of Neuroscience 2020, 131: 984-993. PMID: 32423354, DOI: 10.1080/00207454.2020.1766459.Peer-Reviewed Original ResearchConceptsHealthy controlsRegional cortical thicknessCortical thicknessGyrification indexCortical thinningDisease patientsGI reductionDesikan-Killiany atlasNormal healthy controlsPD-CNParkinson's disease patientsWidespread cortical thinningCortico-cortical connectivityClinical variablesPD-CIParkinson's diseaseDisease pathophysiologyNormal cognitionTemporal regionsROC analysisBrain surfaceAnatomical MRIBrain ROIsPatientsSuch alterations