Polarized Secretion of Drosophila EGFR Ligand from Photoreceptor Neurons Is Controlled by ER Localization of the Ligand-Processing Machinery
Yogev S, Schejter ED, Shilo BZ. Polarized Secretion of Drosophila EGFR Ligand from Photoreceptor Neurons Is Controlled by ER Localization of the Ligand-Processing Machinery. PLOS Biology 2010, 8: e1000505. PMID: 20957186, PMCID: PMC2950126, DOI: 10.1371/journal.pbio.1000505.Peer-Reviewed Original ResearchConceptsRhomboid 3Photoreceptor neuronsEndoplasmic reticulum localizationAxonal terminiDrosophila visual systemRhomboid proteasesLigand SpitzTrafficking stepsER localizationSubcellular localizationPolarized secretionEGFR ligandsPhotoreceptor axonsCell bodiesTerminusLocalizationNeuronal cell bodiesSecretionTraffickingMachineryProteinERNeuronsProteaseAxons